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The interaction between PEO-PPO-PEO triblock copolymers and ionic surfactants in aqueous solution studied using light scattering and calorimetry

Properties of nonionic triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) (EOnPOmEOn) in aqueous solution and their interaction with the ionic surfactants sodium dodecyl sulfate and hexadecyltrimethylammonium chloride have been investigated by static and dynamic light scattering, high sensitivity differential scanning, and isothermal titration calorimetry. The studie

Abnormal retinal vascular morphology in young adults following intrauterine growth restriction

Objective. Intrauterine growth restriction ( IUGR) resulting in low birth weight for gestational age may predispose one to development of cardiovascular disease later in life. Abnormal fetal blood flow in the presence of fetal growth restriction helps to distinguish infants with true fetal growth impairment from small but normal infants. Our goal was to investigate associations between IUGR with a

Exudation of plasma and production of thromboxane in human bronchi after local bradykinin challenge

Plasma exudation has been suggested to be an important component of the inflammatory response in asthma. Bradykinin elicits many of the features of asthma, including bronchoconstriction, cough, plasma exudation and mucus secretion. In an attempt to quantify local plasma exudation, we have employed a novel low-trauma technique with the aim of challenging and lavaging a central part of the bronchial

Management of postmenopausal bleeding in Sweden: a need for increased use of hydrosonography and hysteroscopy.

Background. The objective was to determine how postmenopausal bleeding (PMB) is managed in Sweden today, and to relate the findings to a new evidence-based algorithm for the management of PMB. Methods. A questionnaire regarding the role of ultrasound and the use of different endometrial biopsy methods in the management of PMB was sent to all 61 gynecologic departments in Sweden. Results. Fifty-n

Diagnostic stability in adolescent onset psychotic disorders

The purpose was to examine the long-term stability of a diagnosis of psychotic disorder in adolescence and to focus on diagnostic change over time. A total of 88 patients with a first episode of early onset psychosis (before 19 years) were followed up an average of 10.5 years (range 5.1-18.2) after admission. This report includes the 68 patients who could be traced and interviewed with the Positiv

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns

To investigate the phenotype associated with estrogen receptor alpha (ER) expression in breast carcinoma, gene expression profiles of 58 node-negative breast carcinomas discordant for ER status were determined using DNA microarray technology. Using artificial neural networks as well as standard hierarchical clustering techniques, the tumors could be classified according to ER status, and a list of

Vertebrate host specificity of wild-caught blackflies revealed by mitochondrial DNA in blood

Blood-feeding blackflies (Diptera: Simuliidae) transmit pathogens, harass vertebrate hosts and may cause lethal injuries in attacked victims, but with traditional methods it has proved difficult to identify their hosts. By matching mitochondrial DNA (mtDNA) sequences in blood collected from engorged blackflies with stored sequences in the GenBank database, relationships between 17 blackfly species

Evolution of a carbohydrate binding module into a protein-specific binder

A carbohydrate binding module, CBM4-2, derived front the xylanase (Xyn 10A) of Rhodothermus marinus has been used as a scaffold for molecular diversification. Its binding specificity has been evolved to recognise a quite different target, a human monoclonal IgG4. In order to understand the basis for this drastic change in specificity we have further investigated the target recognition of the IgG4-

Practical Application of Control Theory to Web Services

This tutorial describes experiences with applying a control theoretical approach to achieving performance guarantees in Web servers, with emphasis on delay control. A model for the server is formulated and translated into a control problem formulation. Limitations of the control theoretic approach are identified that arise due to system non-linearities and modeling inaccuracies. Solutions are prop

Soil microfungi in three Swedish coniferous forests

Microfungi were isolated by the soil washing technique from 5 soil horizons in each of 3 podzolic coniferous forests: Picea abies at Kongalund, S. Sweden, Pinus sylvestris at Ivantjarnsheden and P. abies/P. sylvestris at Nickobacken (both central Sweden). A total of 126 species was identified, of which 45 were found at 3, and 24 at 2 of the sites. Mortierella and Penicillium were the commonest gen

Acute changes in cerebral oxygenation and cerebral blood volume in preterm infants during surfactant treatment

Following administration of surfactant a marked depression in aEEG activity occurs for about 10 minutes; the mechanism of this depression is unknown. In view of this, twenty-nine preterm infants were investigated with near infrared spectroscopy (NIRS) to evaluate rapid changes in total cerebral haemoglobin concentration and cerebral oxyhaemoglobin concentration during rescue treatment with natural

Synthesis and characterization of new thioether derivatives of [Os3(CO)12] and [H2Os3(CO)10]; crystal and molecular structures of [Os3(CO)11(L)] [Et2S, Pr2S, S(CH2)5] and [Os3(CO)9(m-H)(m-X){SMe(But)}] (X = H, OH)

Reaction of [Os3(CO)11(NCMe)] with R2S (R = Et, nPr) and MeSBut results in the formation of [Os3(CO)11(L)] (L = thioether) clusters in which the thioethers are coordinated in an equatorial site of the triosmium framework. Such monosubstituted clusters are also formed when [Os3(CO)10(NCMe)2] is reacted with R2S (R = Et, nPr) while reaction of the same cluster with Ph2S or MeSPh results in the forma