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Measurements of the distal airspaces in children using the novel AiDA technique
Estimating minute ventilation from accelerometer data to assess individual exposure of air pollution in preschool children
Infant responses to direct gaze and associations to autism : A live eye-tracking study
When other people look directly towards us, we often respond by looking back at them, and such direct-gaze responses are important for establishing eye contact. Atypical eye contact is common in autism, but how and when this aspect of autism develops is not well understood. Here, we studied whether how much and how quickly infants respond to others' direct gaze is associated with autism in toddler
Different Means to an end: Exploring the Methods and Objectives of the Youth Climate Movement
In September 2019, streets across the world filled with millions of children and youth demanding climate action, demonstrating the growing concern young people feel about their futures (Taylor, Watts, & Bartlett, 2019). However, protests are only one of the methods youths use to show their dissatisfaction with current climate change policies. Youth are also utilizing education, entrepreneurshi
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Perforation Potential in Life Cycle Assessment: a Method for the Identification of Land Use Activities in Remote Areas
Anthropogenically land cover modifications and human presence in natural environments are not without consequences to ecological processes. From a conservation perspective, these consequences are worrisome specially when considering the human domination of terrestrial ecosystems worldwide. The recent loss of wilderness areas has been described as catastrophic despite pro-active conservation scheme
The role of work and social protection systems in social-ecological transformations: Insights from deliberative citizen forums in Sweden
To avoid catastrophic consequences of impending ecological crises our socio-economic systems need to be transformed in rapid and radical manners. Focusing on working life and Sweden as an example for countries of the Global North with a social-democratic welfare tradition, we ask how social protection systems may be reorganised according to the concept of ‘sustainable welfare’, the satisfaction of
The influence of methylphenidate on auditory brainstem response patients with attention deficit hyperactivity disorder; an exploratory study
Background:Attention-deficit hyperactivity disorder (ADHD), characterized by periods of inattention, overactivity, and impulsiveness, is the most prevalent neurodevelopmental disorder among children. Auditory Brainstem Response (ABR) is a technique in which clickshaped sounds elicit potentials that are recorded from electrodes placed on a patient’s skull. Extant research indicates that ABR is freq
Food sovereignty: Empowering Indigenous peoples in the face of globalisation and climate change. A case-based research study from Oaxaca, Mexico
Worldwide, Indigenous peoples have played a critical role in preserving ecosystems and biodiversity. Historically oppressed by colonial institutions, they are today confronted with detrimental effects of the global food system and increasingly pronounced changes in climate that jeopardise their ability to produce food. In reaction to globalisation, food sovereignty advocates the right of peoples t
Restoring antitumor immunity with dendritic cell reprogramming strategies. Reprogramming cancer cells to antigen-presenting cells.
For the past two decades, immunotherapy revolutionized cancer treatment. However, responses vary significantly among eligible patients and some cancer types are not yet open to immunotherapy. Several mechanisms contribute to immunotherapy resistance, including loss of antigen presentation machinery and immunosuppression. Conventional dendritic cells type 1 (cDC1) are a rare population of professio
A Simple Test Case for Convergence Order in Time and Energy Conservation of Black-Box Coupling Schemes
The most commonly used coupling schemes in partitioned multiphysics simulations suffer from a decrease in the order of convergence, specifically in the time domain; a phenomenon we call order degradation. This paper discusses when this issue arises and how it can be studied with a simple example. We present a simple mass-spring system of ordinary differential equations (ODEs) to analyze accuracy a
Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds
Galectins play biological roles in immune regulation and tumor progression. Ligands with high affinity for the shallow, hydrophilic galectin-3 ligand binding site rely primarily on a galactose core with appended aryltriazole moieties, making hydrophobic interactions and π-stacking. We designed and synthesized phenyl sulfone, sulfoxide, and sulfide-triazolyl thiogalactoside derivatives to create af
Childhood neighborhoods and cause-specific adult mortality in Sweden 1939–2015
The socioeconomic health gradient has widened in recent decades. We study how childhood socioeconomic neighborhood conditions influence gender- and cause-specific adult mortality. Using uniquely detailed geocoded longitudinal microdata for a Swedish town (1939–1967), with a follow-up in national registers (1968–2015), we apply Cox proportional hazards models and estimate individual neighborhoods a
Can Parfit′s Appeal to Incommensurabilities Block the Continuum Argument for the Repugnant Conclusion?
Small-scale freshwater aquaculture, income generation and food security in rural Madagascar
Small-scale production has come to the forefront of debates on just and sustainable transformations of food systems because of their potential contributions to communities’ livelihoods and food security. Small-scale freshwater aquaculture holds the promise to positively contribute to income generation and food security [1]. Yet, the evidence of the relationship between them is scarce, particularly
Effects of stochastic vestibular stimulation on cognitive performance in children with ADHD
Previous work has shown that exposure to auditory white noise (WN) can improve cognitive performance in children with ADHD, but it is unknown whether this improvement generalizes to other sensory modalities. To address this knowledge gap, we tested the effect of Stochastic Vestibular Stimulation (SVS) on cognitive performance and reaction time (RT) variability in two groups: children with ADHD and
Acoustophoretic Characterization and Separation of Blood Cells in Acoustic Impedance Gradients
Single-cell phenotyping based on biophysical properties is a promising tool to distinguish cell types and their response to a given condition, and charting such properties also enables optimization of cell separations. Isoacoustic focusing, where cells migrate to their points of zero acoustic contrast in an acoustic impedance gradient, added the effective acoustic impedance of cells to the directo
Getting Personal : The Intuition of Neutrality Reinterpreted
According to the Intuition of Neutrality, there is a range of well-being levels such that adding people with lives at these levels doesn’t make the world either better or worse. As lives in the neutral range can be good for those who live them, this intuition is in conflict with one of the main tenets of welfarism; it creates a disparity between what is good for a person and what is impersonally g
Crop diversification across scales : implications for resource use and cropping systems sustainability
The industrialization of agriculture and efforts to maximize yields of commodity crops are major drivers of biodiversity loss and disruption of ecosystems balance. To become more sustainable, agriculture needs to be aligned with the delivery of multiple ecosystem services, and reduce its dependency on external inputs and its negative environmental impacts. Increasing crop diversity may be a key st