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Risk stratification in congestive heart failure patients using a model-based approach to heart rate turbulence characterization

Heart rate turbulence (HRT) is commonly assessed by two parameters: turbulence onset (TO) and turbulence slope (TS), both obtained by averaging RR tachograms following a ventricular premature beat (VPB). It has been recently shown that a model-based detection-theoretical approach results in HRT indices outperforming TO/TS in identifying the presence or absence of HRT. The aim of this work is to ev

Exercise testing for non-invasive assessment of atrial electrophysiology in patients with persistent atrial fibrillation

The abstract with its heading should not be more than 75 mm long. This is equivalent to 18 lines of text. Leave 1 line space at the bottom of the abstract before continuing with the next heading. The autonomic nervous system modulates atrial electrophysiology in atrial fibrillation (AF). The purpose of this study was (1) to non-invasively characterize the effects of exercise on atrial fibrillatory

Från evidensbaserad medicin till kliniskt kunskapsstöd

Allmänmedicin är ett brett område som spänner över många sjukdomstillstånd, med fokus på patientcentrering. Inom många områden sker en snabb kunskapsutveckling och rekommendationer för utrednings- och behandlingsstrategier uppdateras hela tiden. För en allmänläkare kan det vara svårt att hålla sig uppdaterad och tidsbrist begränsar möjligheterna att leta kunskap i det dagliga kliniska arbetet. Dig

Regulation of norepinephrine transporter and tyrosine hydroxylase mRNAs after kainic acid-induced seizures

Noradrenergic locus coeruleus (LC) efferents to the forebrain suppress seizures in several models of epilepsy. Using in situ hybridization, we demonstrate that tyrosine hydroxylase (TH) and norepinephrine transporter (NET) but not vesicular monoamine transporter 2 (VMAT2) mRNA levels are transiently elevated in LC neurons following kainic acid-induced status epilepticus. These increases of TH and

Welfare State Supporter and Civil Society Activist: Church of Sweden in the “Refugee Crisis” 2015

2015 was a year of an unprecedented migration from the Middle East to Europe. Sweden received almost 163,000 asylum applications. The civil society, including the former state church, took a notable responsibility. In a situation where the welfare systems are increasingly strained, and both the welfare state and the majority church are re-regulated, we ask: how does this play out in local contexts

Suppression of epileptogenesis by modification of N-methyl-D-aspartate receptor subunit composition

The effects of altered N-methyl-D-aspartate (NMDA) receptor subunit composition on seizure development in kindling epilepsy were assessed in transgenic mice expressing high neuronal levels of NR2D under control of the calcium/calmodulin kinase II alpha subunit (αCaMKII) promoter. The NR2D subunit is normally present at very low levels in the mature forebrain. Transgenic mice showed a marked reduct

Hippocampal synaptic plasticity in mice overexpressing an embryonic subunit of the NMDA receptor

The effects of changing NMDA receptor subunit composition on synaptic plasticity in the hippocampus were analyzed by creating transgenic mice overexpressing NR2D, a predominantly embryonic NMDA receptor subunit. NMDA-evoked currents in the transgenic mice had smaller amplitudes and slower kinetics. The transgenics also displayed age-dependent deficits in synaptic plasticity in area CA1 of the hipp

Interface instabilities of growing hydrides

Formation of metal hydrides is a serious complication that occur when hydride forming metals such as zirconium, niobium, vanadium and magnesium are exposed to long term hydrogen environment. The main concern is that the hydride, as being a brittle material, has very poor fracture mechanical properties. Formation of hydride is associated with transportation of hydrogen along the gradients of increa

Quasi-free-standing monolayer hexagonal boron nitride on Ni

The electronic structure of monolayer hexagonal boron nitride grown on Ni by the diffusion and precipitation method was studied by x-ray absorption spectroscopy, emission spectroscopy, x-ray photoelectron spectroscopy and micro-ultraviolet photoemission spectroscopy. No indication of hybridization between h-BN π and Ni 3d orbitals was observed. That is, the monolayer h-BN was found to be in the qu

Large take-off angle dependence of C-K emission spectra observed in highly oriented pyrolytic graphite

We have constructed a compact soft X-ray emission spectrometer at the BL-09A beamline of the NewSUBARU synchrotron radiation facility at the University of Hyogo, Japan. Using this spectrometer, we observed a large take-off angle dependence of C-K emissions in highly oriented pyrolytic graphite (HOPG). At an excitation photon energy of 310 eV, far from the absorption edge of HOPG, we detected large

Solvation dependence of valence electronic states of water diluted in organic solvents probed by soft X-ray spectroscopy

Knowledge of hydrogen bonds is important in a wide range of scientific fields. However, information on the electronic state of hydrogen bonded molecules in liquids and solutions is still limited. We applied X-ray emission and absorption spectroscopy to observe the electronic state around oxygen of water and investigate the solvent dependence of occupied and unoccupied valence electronic states of

Sources of soil dissolved organic carbon in a mixed agricultural and forested watershed in Rwanda

Dissolved organic carbon (DOC) plays a key role in linking terrestrial and aquatic carbon cycles. Most of the work on soil and water DOC has been conducted in temperate watersheds. There is still a gap in knowledge on DOC dynamics within the tropics. This study assesses water extractable organic carbon (WEOC) in topsoils and describes the relationship between WEOC and land use/land cover (LULC), s

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This article explores the genesis of the diplomatic law of international organizations in science and the doctrine of international law of Uzbekistan. The theoretical principles and the legal content of the diplomatic law of international organizations are learned. The inter-branch nature of the diplomatic law of international organizations as the sub-branch of law is disclosed.

Validity of a computer-based risk assessment method for visual ergonomics

ObjectiveTo describe the development of a computer-based risk assessment method for visual ergonomics, and assess its face validity, content validity, and internal consistency.MethodsThe risk assessment method contained a questionnaire for the worker, an evaluation form for the evaluator, a section of follow-up questions based on the worker's responses, and a section for recommended changes, inclu

Atmospheric CO2 inversions on the mesoscale using data-driven prior uncertainties : quantification of the European terrestrial CO2 fluxes

Optimized biogenic carbon fluxes for Europe wereestimated from high-resolution regional-scale inversions, uti-lizing atmospheric CO2measurements at 16 stations for theyear 2007. Additional sensitivity tests with different data-driven error structures were performed. As the atmosphericnetwork is rather sparse and consequently contains large spa-tial gaps, we use a priori biospheric fluxes to furthe

eHealth Services in the Near and Distant Future in Swedish Home Care Nursing

Sweden and other developed countries are putting deliberate efforts into eHealth and digitalization of home care nursing. eHealth services have big potential in this area because they can provide mobile access to healthcare information. This study explores the eHealth services that home care nursing providers in Sweden currently use, plan to use, and have discarded. It also investigates their eHea