Climate change affects human health in a myriad of ways, requiring reassessment of the nature of scaling up care delivery and the effect that care delivery has on the environment. 5 billion people do not have access to safe and timely surgical care, and the quantity and severity of conditions that require surgical, obstetric, and anaesthesia care will increase substantially as a result of climate

Capsule endoscopy (CE) is indicated as a first-line clinical examination for the detection of small-bowel pathology, and there is an ever-growing drive for it to become a method for the screening of the entire gastrointestinal tract (GI). Although CE's main function is diagnosis, the research for therapeutic capabilities has intensified to make therapeutic capsule endoscopy (TCE) a target within r

The aim was to investigate embryo-foetal effects of continuous maternal insulin-induced hypoglycaemia extending throughout gestation or until gestation day (GD)17 (typical last day of dosing during pre-clinical evaluation) providing comparator data for safety assessment of longer-acting insulin analogues in non-diabetic rats. Pregnant rats received human insulin (HI)-infusion during gestation unti

In this contribution we present a constitutive modelling framework for magnetic shape memory alloys (MSMA) that builds on a global variational principle. The approach relies on concepts of energy relaxation and generalised notions of convexity to compute effective energy hulls to the non-convex energy landscape associated with the underlying multi-phase solid, from which the prediction of microstr

Background: Evidence-based guidelines are needed for effective delivery of home oxygen therapy to appropriate patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD). Methods: The multidisciplinary panel created six research questions using a modified Delphi approach. A systematic review of the literature was completed, and the Grading of Recommendations Asse

Controlling infinite dimensional models remains a challenging task for many practitioners since they are not suitable for traditional control design techniques or will result in a high-order controller too complex for implementation. Therefore, the model or the controller need to be reduced to an acceptable dimension, which is time-consuming, requires some expertise and may introduce numerical err

During conditioned food aversion — a.k.a. sauce béarnaise syndrome — the ingestion of a spoiled food item leads to a lasting aversion towards cues reminiscent of the item. A new study finds that, in Drosophila, taste aversion depends on the immune system and the mushroom body.

The development of environmental certification schemes has increased rapidly during the last twenty years and are often used as benchmarks during design of new buildings or reconstruction. However, for management of our existing buildings the members of Sweden Green Building Council request for clear guidelines and a certification scheme. Therefore, a new certification scheme called Miljöbyggnad i

Evaporation is one of the vital components of hydrological cycle. Precise estimation of pan evaporation (Epan) is essential for the sustainable water resources management. The current study proposed a novel approach to estimate daily Epan across the humid region of Iran using support vector regression (SVR) technique coupled with Krill Herd Algorithm (SVR-KHA). Meteorological data were collected f

Root zone temperature is one of the most important soil characteristics, controlling many of the physical, chemical and biological processes in the soil. Temperature varies by soil depth, and exerts a profound impact on plant germination and growth. In this study, the accuracy of two artificial intelligence models including support vector regression (SVR) and elman neural network (ENN) and their h

Field capacity (FC) and permanent wilting point (PWP) are two important properties of the soil when the soil moisture is concerned. Since the determination of these parameters is expensive and time-consuming, this study aims to develop and evaluate a new hybrid of artificial neural network model coupled with a whale optimization algorithm (ANN-WOA) as a meta-heuristic optimization tool in defining

The Molare Rock shelter (S. Giovanni a Piro, Salerno, Italy) is a key site to carry out high-resolution chronological studies in the broader context of Italian Mousterian peopling dynamics. The stratigraphic sequence is to be referred to MIS 5 and is characterized by the presence of a number of thin anthropic levels (often consisting of largely undisturbed living floors) alternated with sterile la

Research and development of novel molecular compounds in the pharmaceutical industry can be highly costly. Lack of confidentiality can prevent a product from being patented or commercialized. As an effect, cross-organizational collaboration is virtually non-existent. In this paper, we introduce a blockchain-based solution to the collaborative drug discovery problem so that participants can maintai

The central role of the certificate authority (CA) in traditional public key infrastructure (PKI) makes it fragile and prone to compromises and operational failures. Maintaining CAs and revocation lists is demanding especially in loosely-connected and large systems. Log-based PKIs have been proposed as a remedy but they do not solve the problem effectively. We provide a general model and a solutio

Ammonia (NH3) is considered a promising alternative fuel, capable of producing energy with zero CO2 emissions. Its combustion, however, poses a series of challenges due to the low reactivity of NH3 and the formation of very high quantities of NOx. This work numerically investigates the combustion and emission characteristics of ammonia in three modern stationary gas turbine concepts, namely (a) le

Advanced treatment technologies for the removal of pharmaceuticals and other organic micropollutants in WWTPs primarily target the removal of parent compounds. Nevertheless, the removal of metabolites originating from human- or microbial metabolism during biological treatment needs comparable consideration, as some of them might be present in high concentrations and contribute to toxicity. This st

Circular oriented innovation commonly requires collaboration. Yet, to date, circular research lacks empirical investigation into collaborative processes. Collaborative processes are, however, highly researched within strategic management literature, thus offering valuable insights. The purpose of this paper is to investigate, identify and order the processes that companies undertake when designing

This consensus statement is the product of the Second International Think Tank on Athlete Mental Health, held on the initiative of the International Society of Sport Psychology. The purposes of the Think Tank were to engage international sport psychology societies and organisations in a discussion about athlete mental health as embedded in an Olympic/Paralympic cycle, and to develop practical reco

INTRODUCTION: Drug-resistant epilepsy patients show worse outcomes after resection when standard neuroimaging is nonlesional, which occurs in one-third of patients. In prior work, we employed 2-D glutamate imaging, Glutamate Chemical Exchange Saturation Transfer (GluCEST), to lateralize seizure onset in nonlesional temporal lobe epilepsy (TLE) based on increased ipsilateral GluCEST signal in the t