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Changes in T-Peak-to-T-End Morphology Measured by Time-Warping are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model

In this work, we use a time-warping-based morphology variation index, d_{w}, computed between the peak and the end of the T-wave, and assess its association with the occurrence of ventricular fibrillation (VF) episodes in ischemic conditions. ECG recordings from 26 pigs under-going a 40-minute coronary occlusion were analyzed. The d_{w} series was obtained by quantifying the morphological differen

Standing to Praise

This paper argues that praise is governed by a norm of standing, namely the evaluative commitment condition. Even when the target of praise is praiseworthy and known to be so by the praiser, praise can be inappropriate owing to the praiser's lacking the relevant evaluative commitment. I propose that uncommitted praisers lack the standing to praise in that, owing to their lack of commitment to the

Ventifacts and wind deflation surfaces in context with glaciofluvial sediment successions in southern Sweden – their age and implication for glacial history

Recent suggestions propose that the glacial landscape in southern Sweden is primarily a relict from the Saalian glaciation (>130 ka). The arguments for this standpoint are the assertion that the majority of glaciofluvial deposits in this region are till-covered, and that wind-abraded clasts are observed at the contact between glaciofluvial sediments and till at numerous locations. Furthermore, it

Agent-Based Life Cycle Assessment enables joint economic-environmental analysis of policy to support agricultural biomass for biofuels

Production of agricultural biofuels is expected to rise due to increasing climate change mitigation ambitions. Policy interventions promoting targeted bioenergy solutions can be motivated by the large environmental externalities present in agricultural systems and the local context of biomass production co-benefits. Introducing energy crops in crop rotations in arable land with depleted Soil Organ

Diverticulosis and risk of diverticulitis in 10 years; a Swedish retrospective observational study

Background: Diverticulosis is a common condition and is thought to be increasing in the Western population. Several studies have attempted to estimate the prevalence of diverticulosis and it’s inflamed state, diverticulitis, with results varying depending on study population and methodology, The aim of this study was to investigate the prevalence of diverticulosis in patients undergoing colonoscop

Numerical Reconstruction of Proton Exchange Membrane Fuel Cell Gas Diffusion Layers

Stochastic reconstruction is widely employed for effective and flexible imitation of Gas Diffusion Layers (GDLs), e.g., to facilitate the study of their properties. However, the reconstruction often overlooks crucial factors such as fiber curvature, fiber stack arrangement, and fiber anisotropy. Consequently, the impact of these structural characteristics remains poorly understood. In this study,

Between Regulatory Fixity and Flexibility in the EU AI Act

The EU AI Act aims to regulate artificial intelligence (AI) in a way that balances innovation and protection from harms, but faces the challenge of keeping pace with the fast and dynamic development of AI. This paper examines the tension between fixity and flexibility when regulating emerging technologies, drawing on literature on the so-called pacing problem, contrasted by sociolegal theory on th

Osteosarcomas With Few Chromosomal Alterations or Adult Onset Are Genetically Heterogeneous

Osteosarcoma is the most common primary bone malignancy, often detected in children and adolescents and commonly associated with TP53 alterations along with a high number of chromosomal rearrangements. However, osteosarcoma can affect patients of any age, and some tumors display less genetic complexity. Besides TP53 variants, data on key driving mutations are lacking for many osteosarcomas, partic

Children in Custody Disputes. : Matching Legal Proceedings to Problems

This open access anthology explores how legal proceedings in and out-of-court can be matched to the complex problems underlying disputes concerning child custody, residence and contact between parents. It focuses particularly on Nordic experiences of in and out-of-court mechanisms as means of resolving custody disputes. The findings by the internationally renowned contributors speak to an internat

New trends in digital diplomacy : The rise of TikTok and the geopolitics of algorithmic governance

TikTok’s viral short-video app has seen tremendous global growth, but its adoption in foreign policy and digital diplomacy is still low. Some diplomatic actors have refrained from developing a presence on TikTok due to geopolitical concerns emerging from TikTok’s Chinese ownership. Other diplomatic actors have established a presence on the platform due to its ability to make content with high enga

IL-23 to see : Gut DCs shine bright in inductive sites

The cytokine IL-23 plays important roles in intestinal barrier protection and integrity, but is also linked to chronic inflammation. In this issue of JEM, Ohara et al. (https://doi.org/10.1084/jem.20230923) provide clarity on the much-debated question of which cells produce IL-23.

Variational Pair-Density Functional Theory : Dealing with Strong Correlation at the Protein Scale

Multiconfigurational pair-density functional theory (MC-PDFT) offers a promising solution to the challenges faced by traditional density functional theory (DFT) in addressing molecular systems containing transition metals, open-shells, or strong correlations in general. By utilizing both the density and on-top pair-density, MC-PDFT can make use of a more flexible multiconfigurational wave function