Addictive disorders are characterized by cognitive, behavioral, and neurological impairments caused by dysregulations of brain structure that can extend well beyond early withdrawal in the months and years of recovery. The present study aimed to examine the efficacy of neurofeedback rehabilitation on anxiety in methamphetamine abusers. The sample consisted of 14 male methamphetamine drug addicts w

This chapter discusses Bergman’s potential worth in the commercial film market on the basis of the director’s own correspondence with potential co-producers and international distributors of his films. The author first studies Bergman’s ample correspondence with Carl Anders Dymling, the powerful head of the Swedish production company Svensk Filmindustri between 1942 and 1961; most of Bergman’s ear

BACKGROUND: Environmental contamination of norovirus (NoV) is believed to be a significant source for further transmission in hospitals.AIM: To investigate the risk of acquiring NoV in a cleaned room previously occupied by a patient with NoV infection. The risk of having a roommate with recent NoV infection was also assessed.METHODS: In a retrospective cohort, comprising 33,788 room stays at five

Climate change threatens tropical coastal communities and ecosystems. Governments, resource managers, and communities recognize the value of assessing the social and ecological impacts of climate change, but there is little consensus on the most effective framework to support vulnerability and adaptation assessments. The framework presented in this research is based on a gap analysis developed fro

Knowledge remains limited on how the structure of microbial community in paddy soils changes in relation to different types of fertilizers with same amount of nutrients. Thus, here, soil samples were collected at 0–10, 10–20, 20–30, and 30–40 cm depths from a paddy field subjected to four long-term fertilization treatments (no fertilization, mineral fertilization, mineral fertilization combined wi

The article first rehearses three deflationary theories of reference, (1) disquotationalism, (2) propositionalism (Horwich), and (3) the anaphoric theory (Brandom), and raises a number of objections against them. It turns out that each corresponds to a closely related theory of truth, and that these are subject to analogous criticisms to a surprisingly high extent. I then present a theory of my ow

Femtio år har gått sedan den klassiska retorikens "återupptäckt". Sedan dess har intresset för ämnet vuxit i västvärlden generellt och i Norden men i Finland återfinns ämnet inte bland de akademiska disciplinerna. I denna artikel presenteras kort retorikundervisningens nuläge i Norden, retoriken som vetenskap i en historisk översikt samt en tentativ kartläggning över ämnets ställning vid Finlands

In-order to meet today’s stringent emission regulations of the European Union, the use of low-carbon fuels in ICE, for instance, Natural Gas (CNG)1 is on the limelight. Due to the high knock-resisting properties of methane (high octane rating), the SI (Spark-Ignition) combustion process is the best match with CNG1. A major disadvantage with an SI engine is its low thermal efficiency mainly due to

The aim of this randomised controlled trial was to compare the costs and benefits of computer-based 2-dimensional and 3-dimensional predictions in orthognathic surgery.Subjects aged 18–30 years with severe class III malocclusion had their treatment planned with both 2- and 3-dimensional techniques. They were randomised in a 1:1 ratio for one or other planning technique. Costs (financial, time, and

Genetic alteration in TP53 gene can proliferate the tumor formation in gastric cancer and the frequency of these somatic mutations can vary in different geographical populations. In the present study, sequencing of the coding regions of TP53 gene, real time gene expression and immunohistochemistry analysis were performed in gastric tumor samples. H. pylori infected tumor, with or without cagA geno

Aim: The aim of this study is to identify the AKT1 gene mutation driven pathogenicity in gastric cancer for Mizo population. Methods: 50 diffuse-type gastric tumors were analyzed for AKT1 exon 2 and 14 mutations. Cell-cycle aberration was analyzed in the AKT1-mutated samples and the stability of the protein as well as exonic splicing enhancer motifs were examined. Results: The novel mutations, 155

Background: The aim of this study was to evaluate the risk of gastric cancer associated with individual or combined glutathione S-transferases (GSTs) polymorphism and their interaction with environmental factors. Materials and Methods: Genotyping by PCR was carried out for 80 cases and controls each for GSTM1, GSTT1, and GSTP1 polymorphism and mapped for gene—environment association studies. The s

Conjugate addition of lithium methylcyanocuprate to the titlealdehydes proceeded with high diastereoselectivity (d.e. 94%). Methyl lithium 1,2-addition, followed by Swern oxidation of the resultingalcohols, gave benzyl botryodiplodin and benzyl epi-botryodiplodin.Hydrogenolysis of the benzyl groups gave the enantiomeric pairs ofbotryodiplodin 10r and 10s and epi-botryodiplodin (9r and 9s).

Acyloxymethylation of an acylated silver salt of α-trinositol gives, after deprotection, membrane permeable 1D-myo-inositol 1,2,6-tris(ethoxycarbonyloxymethyl sodium phosphate). The acyl groups, 3-(4,5-methylenedioxy-2-nitrophenyl)propanoyl, are cleaved by hydrogenolysis.

α-Trinositol analogues, including methyl ethers, deoxy, oxa and aza derivatives were prepared. The parent compound possesses weak analgesic and anti-inflammatory properties. Removal of the non-phosphorylated hydroxyls generates a compound devoid of analgesic activity but which retains the anti-inflammatory property of the parent compound. The protection of these hydroxyls as methyl ethers lends to

Using molecular dynamics simulations in an explicit aqueous solvent, we examine the binding of fluoride versus iodide to a spherical macromolecule with both hydrophobic and positively charged patches. Rationalizing our observations, we divide the ion association interaction into two mechanisms: (1) poorly solvated iodide ions are attracted to hydrophobic surface patches, while (2) the strongly sol

The present minireview of the place of cystatin C in clinical medicine emphasizes, and discuss the evidence, that cystatin C-based GFR-estimating equations do not require the use of vague terms like race and sex, that cystatin C-based GFR-esti mating equations are useful for both children and adults, including the elderly, that the best GFR-estimation requires simultaneous use of both cystatin C-

European populations are ethnically and culturally diverse due to international migration. Evidence indicates large ethnic inequalities in the prevalence of type 2 diabetes. This review discusses the burden of type 2 diabetes and its related complications, and the potential explanatory mechanisms among migrants in Europe. The current available data suggest that the rate of type 2 diabetes is highe