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Methods and Software for Digital Spatial Proteomic Profiling data

Utveckling av metoder och interaktiva webbapplikationer för analys av spatiell cancerdata. Immunterapi är en nyare behandlingsform som bygger på att kroppens egna immunförsvar tar sig an cancercellerna. Den är effektiv och leder i regel till färre biverkningar än klassiska behandlingar, såsom kemoterapi eller strålning. Tyvärr svarar inte alla cancertyper på Immunterapi. Äggstockscancer är ett exTechnical development often precedes scientific breakthrough but can also pose new challenges to the scientific community. This is the case for Digital Spatial Profiling (DSP), where recent breakthroughs allow for collecting multi-plex spatial proteomic/transcriptomic data from tissue and it is prophesied a promising future in cancer research. A challenge, however, is handling its output data with

Counterfeit products affect on brand equity: A case study on how counterfeit products affect a luxury brand’s brand equity

Purpose: The purpose of this paper is to investigate how counterfeit products affect a brand’s brand equity with the help from a consumer perspective. Research question: What is the consumer’s perception of counterfeit products? How and why does the consumer’s perception of counterfeit products affect a brand’s brand equity? Methodology: This research paper was based on quantitative research,

Occupant loads and COVID-19: The impact on office building fire evacuation

COVID-19 was declared a world-wide pandemic in 2020, consequently affecting societies all around the globe. This thesis investigates one of these effects, namely how the pandemic affected occupant loads in office buildings and its subsequent effect on fire evacuation. Occupant load is one of many important factors when designing a building in regard to its fire safety, as it is a key component in

How does body image relate to brand image? An analysis of brands incorporating the body positivity movement

Purpose: The importance of body positivity is visible in its remarkable media presence. The movement entails challenges such as opportunities for brands. The purpose of this paper is to examine why companies adapt to the body positivity movement, what they are exactly doing regarding body positivity and how this is related to the brand’s reputation. Methodology: Literature and media review, Case

Simulation of periodic counter-current chromatography purification of monoclonal antibodies with column degradation

Uppreningsprocessen av monoklonala antikroppar (mAbs) är dyr, speciellt det kromatografisteg där antikropparna separeras från andra protein och celler i lösningen från tidigare steg i processen. Antikropparna separeras från lösningen med hjälp av affinitetskromatografi, där det endast är antikropparna som interagerar med innehåller i kolonnen och stannar kvar, medan resten passerar obehindrat. AntThe purification process of monoclonal antibodies (mAbs) for therapeutic drugs is expensive, especially the chromatography step in which the mAbs are separated from other proteins and cells present in the feed. The antibodies are separated from the feed using affinity chromatography, where only the antibodies interact with active sites within the column, whereas the rest passes through the column

Original or Originated? An Analysis of the Emergence of Influencer Marketing

Purpose: Explore the evolutionary relationship between celebrity endorsements and the boom of influencer marketing with respect to the consumer demand for authenticity and the repercussions for branding practices moving forward. Methodology: Research was conducted through a literature review, case studies, and historical review. The findings were then analysed and condensed in to a framework to i

Igniting Risk Communication? – Organizational factors for effective risk communication: Forest fire risk communication in Canton Bern, Switzerland

Risk communication forms an integral part of disaster preparedness. In light of the increasing likelihood and intensity of forest fires, areas like Canton Bern in Switzerland, not usually known as a forest fire hotspot, have planned to strengthen their risk communication efforts to help increase overall preparedness and mitigation. Using the example of forest fires, this paper will shed light on t

A Comparative Study Of Proof of Stake Algorithms

Cryptocurrencies are growing at a rapid pace. It is well established that the mining operation fueling the cryptocurrency Bitcoin consumes a significant amount of energy. This study aims to determine if there is an alternative to the consensus model, maintaining security, integrity, and decentralization. It includes a deep dive into the Bitcoin network and the consensus model Proof of Work (PoW ).

Towards Deep Learning Accelerated Sparse Bayesian Frequency Estimation

The Discrete Fourier Transform is the simplest way to obtain the spectrum of a discrete complex signal. This thesis concerns the case when the signal is known to contain a small (unknown) number of frequencies, not limited to the discrete Fourier frequencies, embedded in complex Gaussian noise. A typical signal is generated from a digital radar and the frequency components stem from point scatters

Brands Under Siege

Purpose: To explore how different B2B companies within the plastic industry are adapting and managing their brand under siege in regards to the environmental pressure from stakeholders. Methodology: This study takes a qualitative research approach, combining primary and secondary data. To create an understanding of the plastic industry, three B2B companies were interviewed in order to investigate

Design av en Ruggad Kamera-Styrenhet

I detta projekt utvecklades ett formspråk för militära sensorprodukter. Med särskild vikt på att företagets olika produkter skulle få ett gemensamt vi- suellt uttryck. Detta formspråk tillämpades sedan på styrenheten till en kamera, vilken används utomhus i tuffa förhållanden. Till styrenheten ut- vecklades en lösning för ett kompakt portabelt lagringsmedia som samtidigt går att använda med tjocka

”det är ju inte planerat för att man ska bo på det sättet...”: hur kollektiva hushåll påverkas av arkitekturens materialiserade normer

Architecture can be described as the built variant of culture, and the architecture of the dwelling is particularly affected by norms and assumptions that regulate the way we live and whom we live with. Only 0.05% of dwellings in Sweden are built for collective households and it is therefore worth investigating how they are are affected by a built environment that is not built in consideration of

Evaluation of gold-based compounds as Plasmodium falciparum aquaglyceroporin inhibitors

The efficiency of gold complexes featuring di- or tri-pyridine scaffolds in inhibiting human aquaporins have been previously investigated. They have returned promising results in cancer treatment and have been suggested to be potentially applied against malaria too. ([Au(bipy) Cl_2]+)., ([Au(phen)Cl_2]+) and ([Au(terpy)Cl]2+) in all their possible forms in solution, were computationally studied us

Here Comes the Sun: Imagination, Development, and Technology in Malawi

This paper explores how electrical appliances, together with the idea of attaining energy access in the near future, create hope in a northern village in Malawi. Even though less than one per cent of the rural population has energy access, some of these locals already own solar systems. Nevertheless, their solar equipment is not powerful enough to generate the large amounts of energy required to r

Kvartersbadet

We need places in the city where we can just be, slow down and have experiences that are sensual and bodily. When communal baths were built in the cities of Sweden, it was largely for hygienic reasons, a place where people washed weekly. Now you could say that bathing is a kind of ritual, something that we do for the sake of the experience. I designed the bathhouse on an infill plot in Gamla Väste

Do Postnatal Depression and Anxiety Symptoms "Invade" Attachment Script Narrative Assessment?

Background: Secure base scripts (SBS) comprise implicit procedural expectations about the availability of significant others, and are formed early in life based on experiences with caregivers. SBS are conventionally captured via word-prompted, impersonal narratives, but as this assessment paradigm is relatively new, little is known about how it may be affected by situational mental health problems

Investigating the use of Semiconductor Nanowires for Neural Networks

In this work, we intend to employ nanowires for the realisation of an artificial neuron which can be used to design a neural network that will guide the new generation of non-von Neumann architectures such as Neuromorphic Computing. Possible applications are strongly related to Neuromorphic architectures and artificial intelligence, such as high-performance computers, robotics hardware and autonom