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Tea tree oil attenuates experimental contact dermatitis.

Herbs and minerals have been used in clinical dermatology for hundreds of years and herbal ingredients are becoming increasingly popular with the public in treatment of various dermatological conditions characterised by inflammation and pruritus. The aim of this study was to compare the efficacy of traditional topical therapeutic agents with a moderate potency topical glucocorticoid on experimenta

Galectin-3 endocytosis by carbohydrate independent and dependent pathways in different macrophage like cell types.

BACKGROUND: Galectin-3 (the Mac-2 antigen) is abundantly expressed in both macrophage like cells and certain non-macrophage cells. We have studied endocytosis of galectin-3 as one important step relevant for its function, and compared it between variants of a macrophage like cell line, and non-macrophage cells. METHODS: Endocytosis of galectin-3 was observed by fluorescence microscopy and measur

The Mathematics of Internet Search Engines

This article presents a survey of techniques for ranking results in search engines, with emphasis on link-based ranking methods and the PageRank algorithm. The problem of selecting, in relation to a user search query, the most relevant documents from an unstructured source such as the WWW is discussed in detail. The need for extending classical information retrieval techniques such as boolean sear

Combination of antibodies inhibits accelerated rejection mediated by memory T cells in xenoantigen-primed mice.

Wang F, Xia J, Chen J, Peng Y, Cheng P, Ekberg H, Wang X, Qi Z. Combination of antibodies inhibits accelerated rejection mediated by memory T cells in xenoantigen-primed mice. Xenotransplantation 2010; 17: 460-468. © 2010 John Wiley & Sons A/S. Abstract: Background: Donor-reactive memory T cells are known to accelerate allograft rejection; in our previous study, we reported that combined monoc

Optimum electrolyte composition of a dialysis solution.

In patients undergoing peritoneal dialysis (PD) for end-stage renal failure, the optimum electrolyte composition of a dialysis solution is that which best serves the homeostatic needs of the body. Comparing the transperitoneal removal of electrolytes by conventional PD solutions (CPDSs) with that by normal kidneys, it is evident that peritoneal removal is in the lower range of what can be consider

Up-Regulation of A1M/α(1)-Microglobulin in Skin by Heme and Reactive Oxygen Species Gives Protection from Oxidative Damage.

During bleeding the skin is subjected to oxidative insults from free heme and radicals, generated from extracellular hemoglobin. The lipocalin α(1)-microglobulin (A1M) was recently shown to have reductase properties, reducing heme-proteins and other substrates, and to scavenge heme and radicals. We investigated the expression and localization of A1M in skin and the possible role of A1M in the prot

Effects on sleep-related problems and self-reported health after a change of shift schedule.

This study prospectively examined the effects of a change of shift schedule from a fast forward-rotating schedule to a slowly backward-rotating one. The initial schedule had a forward rotation from mornings to afternoons to nights over 6 consecutive days, with 2 days on each shift followed by 4 days off before the next iteration of the cycle, whereas the new schedule had a slower backward rotation