Gartland type III fracture is the most troublesome type of supracondylar humerus fracture. These injuries most often occur in school age children, but they are seen in pediatric patients of all ages. The goal of this study was to analyze toddlers with Gartland type III fractures to identify clinically significant differences compared with older children. A retrospective cohort study was conducted

Today it is generally accepted that the Bacillus Calmette-Guerin (BCG) vaccine protects against childhood tuberculosis (TB) but this immunity wanes with age, resulting in insufficient protection against adult pulmonary TB. Hence, one possible strategy to improve the protective efficacy of the BCG vaccine would be to boost in adulthood. In this study, using the mouse model, we evaluated the ability

Background: The purpose of this paper is to outline the protocol for the research program “UserInvolve,” with the aim of developing sustainable, service user involvement practices in mental health services in Sweden.Methods: This protocol outlines the knowledge gap and aim of the UserInvolve-program. It further provides an overview of the research infrastructure, with specific focus on the organiz

BackgroundRecovery colleges were developed in England to support the recovery of individuals who have mental health symptoms or mental illness. They have been founded in many countries but there has been little international research on recovery colleges and no studies investigating their staffing, fidelity, or costs. We aimed to characterise recovery colleges internationally, to understand organi

Nocturnal avian migration flyways remain an elusive concept, as we have largely lacked methods to map their full extent. We used the network of European weather radars to investigate nocturnal bird movements at the scale of the European flyway. We mapped the main migration directions and showed the intensity of movement across part of Europe by extracting biological information from 70 weather rad

Truman, J., Collier, L., Mcginley, S., Shiel, A., Fox, J., Hynes, S., Hills, C., Orban, K. & Ekstam., L. (2018). Professional identity – The key to professional survival? Designing a tool to measure the development of professional identity. Paper presented at the Royal College of Occupational Therapists Annual Conference, June 2018, Belfast, UK.

The implementation of circular economy strategies, such as the reuse of building materials, represents a valid opportunity for the building and construction sector to diminish the consumption of raw materials and generate revenues and, thus, to contribute to the Sustainable Development Goals 11 and 12. However, the reuse of building materials is still limited. Previous studies suggest that one rea

Differential cross-section measurements of Zγ production in association with hadronic jets are presented, using the full 139 fb −1 dataset of s = 13 TeV proton–proton collisions collected by the ATLAS detector during Run 2 of the LHC. Distributions are measured using events in which the Z boson decays leptonically and the photon is usually radiated from an initial-state quark. Measurements are mad

Obesity is associated with an increased risk of developing breast cancer (BC) and worse prognosis in BC patients, yet its impact on BC biology remains understudied in humans. This study investigates how the biology of untreated primary BC differs according to patients’ body mass index (BMI) using data from >2,000 patients. We identify several genomic alterations that are differentially prevalent i

This paper presents a method to optimize an electric powertrain platform, capable of addressing the needs of a wide range of vehicle types while taking advantage of economies of scale and reducing time to market. The optimization includes all electric powertrain components from the electrical machine and inverter to the transmission. The objective is to minimize both the operational and electrical

Biallelic variants in the Golgi SNAP receptor complex member 2 gene ( GOSR2) have been reported in progressive myoclonus epilepsy with neurodegeneration. Typical clinical features include ataxia and areflexia during early childhood, followed by seizures, scoliosis, dysarthria, and myoclonus. Here, we report two novel patients from unrelated families with a GOSR2-related disorder and novel genetic

High-precision cellular-based localization is one of the key technologies for next-generation communication systems. In this paper, we investigate the potential of applying machine learning (ML) to a massive multiple-input multiple-output (MIMO) system to enhance localization accuracy. We analyze a new ML-based localization pipeline that has two parallel fully connected neural networks (FCNN). The

BACKGROUND: Although most pediatric radial neck fractures can be treated with either immobilization alone or closed reduction and immobilization, a small subset result in permanent loss of motion despite surgical management. We sought to characterize the most problematic fractures and correlate final outcomes with both presenting fracture characteristics and the reduction achieved through surgical

BACKGROUND: The outcome after weaning from postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO) is poor. In this study, we investigated the prognostic impact of arterial lactate levels at the time of weaning from postcardiotomy VA.METHODS: This analysis included 338 patients from the multicenter PC-ECMO registry with available data on arterial lactate levels at weaning from VA

Oncogene-induced senescence (OIS) is a persistent anti-proliferative response that acts as a barrier against malignant transformation. During OIS, cells undergo dynamic remodeling, which involves alterations in protein and organelle homeostasis through autophagy. Here, we show that ribosomes are selectively targeted for degradation by autophagy during OIS. By characterizing senescence-dependent al

This article presents new measurements of the fragmentation properties of jets in both proton–proton (pp) and heavy-ion collisions with the ALICE experiment at the Large Hadron Collider (LHC). We report distributions of the fraction zr of transverse momentum carried by subjets of radius r within jets of radius R. Charged-particle jets are reconstructed at midrapidity using the anti-k T algorithm w

We review reduction and contraction in modalizing expressions of the type V-to- Vinf from the perspective of production, perception and mental representation.A corpus study of spoken American English shows reduction/contraction asa continuous process which is subject to phonological and communicative constraints. Generally, reduction (articulatory ease) is restricted by a tendencyto retain cues to

Background: Geoeconomic variations in epidemiology, the practice of ventilation, and outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data of four large observational studies. Methods: In this pooled analysis we harmonised individual patien