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Oxidative damage, genetic and epigenetic alterations in hexavalent chromium exposed workers - A cross-sectional study within the SafeChrom project

BACKGROUND: Hexavalent chromium (Cr(VI)) is a lung cancer carcinogen. However, the genotoxic and mutagenic effects of Cr(VI) in humans at low-to-moderate occupational exposure levels are unknown. This study aims to investigate the relationship between occupational exposure to Cr(VI) and the presence of oxidative damage, genetic and epigenetic alterations.METHODS: We included 113 Cr(VI) exposed wor

”Det är världens roligaste jobb” - Att främja delaktighet och musikalisk kunskapsutveckling i anpassad grundskola ur ett musiklärarperspektiv

I den här studien undersöks hur fem musiklärare som är, eller har varit, verksamma i anpassad grundskola beskriver hur de arbetar med musikalisk kunskapsutveckling, delaktighet och måluppfyllelse. Undersökningen baseras på semistrukturerade intervjuer och hela arbetet vilar på socialkonstruktivismen som vetenskapsteori. Ämnesvalet grundar sig i en nyfikenhet kring hur vi som framtida lärare kan arThis study investigates how five music teachers that are, or have been, working in Swedish compulsory school for pupils with intellectual disabilities describe how they are working with development of musical knowledge, inclusion and goal attainment. The study is conducted by using semistructured interviews and is grounded in social constructivism as its scientific theoretical framework. The selec

Care That Cannot Wait - Asylum Seekers’ Access to Sexual and Reproductive Health Care in Sweden

Health inequality and unequal access to health care remain significant problems in Sweden. Migrants report enjoying a lower level of health, both in general and specifically in regard to sexual and reproductive health and rights (SRHR), as recognised by the Swedish Public Health Agency in their 2020 National Strategy. As a subgroup, asylum seekers find themselves at a particularly high vulnerabili

Can Law Keep Up? The AI Act and the Challenges of Evolving Generative AI and Large Language Models

As generative artificial intelligence (“AI”) rapidly transforms sectors, regulators are racing to keep pace with technologies that evolve faster than legal frameworks can adapt. These systems, powered by large language models or foundation models, are not only capable of generating human-like content but also demonstrate behaviors that shift depending on their data, deployment, and interaction con

AI and Copyright law in a European law context

This thesis examines how AI-generated works fit within the European Union’s copyright framework and explores alternative legal mechanisms for their protection. With the emergence of generative AI technologies capable of creating content independently, traditional copyright concepts, particularly authorship and originality are being challenged. The thesis begins by outlining the technological basi

Realising Indigenous Children’s Rights: Aligning the Principles of Self-Determination and the Best Interests of the Child. The Case of Indigenous Peoples in Canada

he historical legacy of colonialism worldwide has created challenges for Indigenous peoples, including racial discrimination and marginalization. This is reflected in, inter alia, the overrepresentation of Indigenous children in child welfare systems, even in countries performing comparably high in human right advancements otherwise. While there may be a broad spectrum of reasons for this issue, t

Att stanna eller lämna: en kvalitativ studie baserad på självbiografier om kvarhållande och frigörande faktorer i kvinnors uppbrottsprocess från våldsamma relationer.

Intimate partner violence is a serious societal issue with far-reaching consequences for women's health, safety, and overall life conditions. This study explores how women who have experienced violence in heterosexual relationships describe their journey toward leaving their abusive partners. By analyzing five autobiographical narratives written by Swedish women, the study seeks to uncover emo

Thai Boys’ Love media as a means of Soft Power among International Students in Thailand

Thai Boys’ Love (BL) media has traveled far beyond its origins. This thesis explored how Thai BL media, especially BL series, has introduced Thailand to foreign fans who have become international students in Thailand. It considered the BL phenomenon from its Japanese Yaoi adaptation to its evolution into mainstream Thai entertainment. Through qualitative interviews with international and exchange

Galactic properties of exoplanet host stars

Mänskligheten har länge varit fascinerad av jordliknande planeter som kretsar kring avlägsna stjärnor. Vi har skickat teleskop ut i rymden för att studera dessa planeter, och för att hitta mönster bland deras egenskaper. Kepler-teleskopet var ett av de första sådana teleskop, och avslöjade den stora variationen av planeter i vår galax. De vanligaste typerna av planeter som hittades var så kallade Context. The radius valley is the bimodal distribution of planet radii Rp = 1 − 3.9R⊕, which separates super-Earths from sub-Neptunes. One possible explanation is that stellar clustering in the birth environment of the host star could cause sub-Neptunes to shed their gaseous envelope and turn into super-Earths (Kruijssen et al., 2020). Using the calculated phase space density of host stars as a me

Effects of Contamination on 4MOST Stellar Spectra

Vi bor i galaxen Vintergatan. En plats som vi kan kalla hemma i ett allt växande universum. Men hur mycket vet vi egentligen om våran galax? Det finns mycket som återstår att upptäcka om våran galax. Ett exempel på någonting som vi inte vet hittas när vi observerar den galaktiska disken. Detta är regionen som expanderar horisontellt från det galaktiska centrumet. Disken är uppdelad i en tunn ochThis paper discusses the effects of different types of contamination on 4MOST stellar spectra. Three main types of contamination were tested. These were, a smooth function over the continuum, changing the H-alpha line, and adding telluric contamination. By knowing how much these experiments affected the generated values, it was possible to understand the importance of avoiding overfitting or under

Lithium Elemental Abundance Determination for 4MOST

Stellar lithium abundances can help answer multiple unanswered questions within modern astrophysics. Lithium is fragile in comparison to other elements found in stellar atmospheres. Consequently, its abundance within the stellar atmosphere is depleted by different processes. Studying these lithium abundances gives insight into the evolution of the stars and the processes within their interiors. Th

Characterization of the Galactic disks using t-SNE and k-means clustering

Problem: The Milky Way disk consists of two distinct components, the thin and thick disk, each with unique kinematical, elemental, and age-related properties. Among all the properties considered, age stands out as the only one that does not exhibit significant overlap, thereby offering clearer separation between the populations. Stellar ages, determined through isochrone fitting, are reliable main

Rolling Out the Green Carpet from Stockholm to Shibuya: Exploring How Swedish Companies Leverage Sustainability and Digitalization in Japan

From a market perspective, Japan is interesting for Swedish companies, especially those with sustainable and digital capabilities. However, the Japanese market is complex, with high quality demands and deep relationships, which require foreign companies to understand how their assets transfer locally. This thesis explores how ten Swedish subsidiaries in Japan use sustainability and digitalization

Managing Carbon, Managing Futures: A Study of Sociotechnical Imaginaries in the Rollout of CCUS in Denmark

Carbon capture utilization and storage (CCUS) is set to play a key role in decarbonization. Most of the technologies are yet to be seen on commercial scale. Denmark is in the process of establishing some of the first large-scale CCUS value-chains. Through a combination of document analysis and interviews, I study the ideas driving the current roll-out of CCUS in Denmark. To do this, I make use of

Glucose-dependent insulinotropic polypeptide (GIP)

Background: Glucose-dependent insulinotropic polypeptide (GIP) was the first incretin identified and plays an essential role in the maintenance of glucose tolerance in healthy humans. Until recently GIP had not been developed as a therapeutic and thus has been overshadowed by the other incretin, glucagon-like peptide 1 (GLP-1), which is the basis for several successful drugs to treat diabetes and

Machine learning identifies remodeling patterns in human lung extracellular matrix

Organ function depends on the three-dimensional integrity of the extracellular matrix (ECM). The structure resulting from the location and association of ECM components is a central regulator of cell behavior, but a dearth of matrix-specific analysis keeps it unresolved. Here, we deploy a high-resolution, 3D ECM mapping method and design a machine-learning powered pipeline to detect and characteri

Impact of tyrosine amination on the aggregation and neurotoxicity of amyloid-β

The tyrosine residue in amyloid-β (Aβ) is susceptible to attack by various reactive nitrogen intermediates, leading to the formation of 3-nitrotyrosine (3-NT), a post-translational modification associated with the pathophysiology of Alzheimer's disease (AD). Although considered a “dead-end” product, emerging evidence suggests that 3-NT can be reduced to 3-aminotyrosine (3-AT) in vivo. This study a

Repackaging Kenya - A Transformation Roadmap Toward a Sustainable Bags and Sacks Industry

This thesis investigates the current state and future potential of Kenya’s bags and sacks packaging industry, with a focus on transitioning toward more sustainable practices. Despite policy efforts like the 2017 single-use plastic bag ban, the industry faces structural and economic barriers to adopting sustainable alternatives. The aim of this study is to assess macro- and micro-level factors shap