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Modelling the impacts of climate and land use change on water security in a semi-arid forested watershed using InVEST
Water security, a key policy objective for sustainable development, is under stress as a result of land use and climate change, especially in (semi-)arid areas like Iran. Land use change alters surface runoff and affects basin-wide hydrological processes and water consumption, while climate change modifies precipitation and temperature patterns and consequently evapotranspiration and water supply.
Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects
Background: Migraine occurs 2–3 times more often in females than in males and is in many females associated with the onset of menstruation. The steroid hormone, 17β-estradiol (estrogen, E2), exerts its effects by binding and activating several estrogen receptors (ERs). Calcitonin gene-related peptide (CGRP) has a strong position in migraine pathophysiology, and interaction with CGRP has resulted i
Historical isolation facilitates species radiation by sexual selection : Insights from Chorthippus grasshoppers
Theoretical and empirical studies have shown that species radiations are facilitated when a trait under divergent natural selection is also involved in sexual selection. It is yet unclear how quick and effective radiations are where assortative mating is unrelated to the ecological environment and primarily results from sexual selection. We address this question using sympatric grasshopper species
Indigenous ecological knowledge in the Colombian Amazon - challenges and prospects for a more sustainable use of local forest fauna
The Amazon rainforests and their biological diversity are being lost rapidly by the onslaught of extractive industries, large-scale agriculture and infrastructure development, which also undermines the integrity of indigenous territories and ethnicities, threatening the tremendous cultural diversity of the Amazon. The loss of forest, the disintegration of local communities and the increase of the
Maximal subgroups of non-torsion Grigorchuk-Gupta-Sidki groups
A Grigorchuk-Gupta-Sidki (GGS-)group is a subgroup of the automorphism group of the p-regular rooted tree for an odd prime p, generated by one rooted automorphism and one directed automorphism. Pervova proved that all torsion GGS-groups do not have maximal subgroups of infinite index. Here we extend the result to non-torsion GGS-groups, which include the weakly regular branch, but not branch, GGS-
Patients' Perceptions of Person-Centered Care in Early Rheumatoid Arthritis: A Qualitative Study
ObjectiveMost research on patient experiences of rheumatoid arthritis (RA) care is performed with patients who have established RA and less often with patients with early RA. Experiences of and expectations about health care may change over time, which is why the aim was to explore patients’ perceptions of person-centered care (PCC) early in the RA disease course.MethodsThirty-one patients with ea
Unmasking the drivers and implementation of change
This paper investigates the drivers for, and implementation of, digital transformation projects and organizational change initiatives in 20 companies in the UK. The study follows on previous research based on the Socio-Technical Toolbox [STT], specifically focusing on the activity analysis and employees’ experience and participation in the change initiative or digital transformation project.
Food sources and access strategies in Ugandan secondary cities : an intersectional analysis
This article arises from an interest in African urbanization and in the food, farming and nutritional transitions that some scholars present as integral to urban life. The paper investigates personal urban food environments, food sources and access strategies in two secondary Ugandan cities, Mbale and Mbarara, drawing on in-depth interviews and applying an intersectional lens. Food sources were si
Translational Motion of Water in Biological Tissues-A Brief Primer
As an introduction to the rigorous treatment of diffusion encoding in the rest of the book, this chapter gives simple non-mathematical explanations of the relations between the properties of biological tissues and the translational motion of the tissue water with the aim of conveying an intuitive feel of the relevant time and length scales and the level of detail of the information that can be obt
Speaking with an alien voice : Flexible sense of agency during vocal production
RIFM fragrance ingredient safety assessment, 2-methyl-4-(camphenyl-8)-cyclohexanone, CAS Registry Number 68901-22-4
“Making the alliance even greater” : (Mis-)managing U.S.-Japan relations in the age of Trump
President Donald Trump’s “America First” policy questions the fundamentals of the global U.S.-led alliance network. Where other allies implemented hedging strategies, Japan’s Prime Minister Abe Shinzō pledged to “make the alliance even greater,” insisting that the bilateral ties were “airtight” and “stronger than ever before.” However, Trump’s approach to trade, détente with North Korea, and off-t
Transforming data to information : A parallel hybrid model for real-time state estimation in lignocellulosic ethanol fermentation
Operating lignocellulosic fermentation processes to produce fuels and chemicals is challenging due to the inherent complexity and variability of the fermentation media. Real-time monitoring is necessary to compensate for these challenges, but the traditional process monitoring methods fail to deliver actionable information that can be used to implement advanced control strategies. In this study, a
VoI-informed decision-making for SHM system arrangement
Structural health monitoring systems have been widely implemented to provide real-time continuous data support and to ensure structural safety in the context of structural integrity management. However, the quantification of the potential benefits of structural health monitoring systems has not yet attracted widespread attention. At the same time, there is an urgent need to develop strategies, suc
Family caregivers’ support needs during allo-HSCT—a longitudinal study
Purpose: The study aimed to explore family caregivers’ support needs prior to allo-HSCT, how these change over time and whether they are associated with demographic factors and caregiver outcome. Methods: This longitudinal repeated measure study included 87 family caregivers of allo-HSCT recipients: 63% were partners, 74% women, 65% lived with the recipient, and their mean age was 54 years. They c
Unions and the rights of migrants in the long run
We use historical data on union density and new historical data on policies toward migrants to study the long-run relationship between the strength of trade unions and the social and economic rights of migrants in the Global North. In countries with strong trade unions, there was, for a long time, a widening distance between the rights of migrants and the rights of citizens, probably because the rWe use historical data on union density and new historical data on policies toward migrants to study the long-run relationship between the strength of trade unions and the social and economic rights of migrants in the Global North. In countries with strong trade unions, there was, for a long time, a widening distance between the rights of migrants and the rights of citizens, probably because the r
Unannounced Evacuation Experiment in a High-Rise Hotel Building with Evacuation Elevators : A Study of Evacuation Behaviour Using Eye-Tracking
Past studies suggest that people are often reluctant to use occupant evacuation elevators in case of fire. However, existing research is scarce and current knowledge is based on questionnaire studies and laboratory experiments. An unannounced evacuation experiment was therefore performed on the 16th floor of a 35-floor high-rise hotel building. Sixty-seven participants took part and eye-tracking g
Trends and Disparities in Subjective Upward Mobility since 1940
Concerns that prospects for upward mobility are fading are common in popular and scientific discourse. The fact that fewer Americans today surpass their parents’ economic status than in the past has been invoked to explain trends ranging from the recent spike in drug and alcohol poisonings to the growing appeal of right-wing populism. Using General Social Survey data, the authors ask whether peopl
Allergome-wide peptide microarrays enable epitope deconvolution in allergen-specific immunotherapy
Background: The interaction of allergens and allergen-specific IgE initiates the allergic cascade after crosslinking of receptors on effector cells. Antibodies of other isotypes may modulate such a reaction. Receptor crosslinking requires binding of antibodies to multiple epitopes on the allergen. Limited information is available on the complexity of the epitope structure of most allergens. Object