Search results

Filter

Filetype

Your search for "*" yielded 531808 hits

Regulation and Function of the Human Leukotriene D4 Receptor CysLT1 in Epithelial Cells and Colon Cancer

Popular Abstract in Swedish Betændelses reaktionen er kroppens svar på en skade eller en infektion. Betændelses reaktionen gør at immunforsvarets celler kaldes til det skadede område (kan ses som den røde varme hævelse omkring et sår) og at eventuelle sygdomsfremkaldende emner identificeres og bekæmpes. På lidt længere sigt, fjernes ødelagt væv og helingen af såret påbegyndes. Når det skadede områThe pro-inflammatory mediators leukotrienes have shown to be important players in the pathogenesis of diseases like asthma and inflammatory bowel disease (IBD). Patients suffering from IBD have been found to have an increased risk of developing colon cancer. Since leukotrienes have been shown in increased concentrations in stools of IBD patients we hypothesise that LTD4 can play a role in the deve

Galiellalactone Synthetic Studies

Popular Abstract in English Prostate cancer is one of the most common causes of death for men. This disease can be detected at different stages and if it is detected at an initial stage there are many therapies to choose from. However, if it is detected at an advanced stage the options are reduced and most of the treatments are aggressive in an effort to extend the patient’s life. The most common In search for remedies and treatments, science has recurred to Mother Nature. This is where galiellalactone was found, a fungal metabolite isolated from Galiella rufa in 1990. Since then chemists and biologists have been studying its properties and found it to be a potential candidate against castration-resistance prostate cancer (CRPC). The development of a new drug requires many studies of the c

Islanding Detection in Power Systems

As the contribution of dispersed or distributed energy resources (DER) to the electric power production increases, the effects on the power system grow more important. As an example a critical situation may arise if protective relays trip a large part of the dispersed generation due to undervoltage at a short-circuit event. On the other hand it is crucial that the protection system acts correctly

Time series of atmospherically distorted wavefronts

A method is described for production of time series of atmospherically distorted wavefronts following Kolmogorov statistics. The method uses Taylor's hypothesis (`frozen turbulence') to generate the temporal development of the aberrations caused by an atmospheric turbulence layer. An arbitrary number of turbulence layers can be used to generate the final wavefront.

Gender in Contemporary Iran

This book examines gender and the dynamics of social change in contemporary Iran, documenting the changes in women's lives and showing how women now have become agents of social change rather than victims. Bringing together the detailed primary research of a number of eminent scholars working in Iran, this collection provides unique perspectives on the past decade in Iranian society and explores t

Development of Techniques for 3D Imaging with Focused Ion Beams - Hydrogen Depth Profiling and Microtomography with Applications in Geology

Popular Abstract in Swedish Inom jonstråleanalysen används en partikelstråle, vanligtvis av protoner eller alfapartiklar, med hög energi för undersökning av prov. Då dessa partiklar skjuts in i provet sker kollisioner, reaktioner eller annan form av växelverkan med elektroner och kärnor i provets inre. En del av dessa processer ger upphov till högenergetisk strålning som kan studeras med lämpliga In nuclear microprobe experiments, high resolution maps of the measured parameter, e.g. element- or mass distribution, in a sample can be produced with a variety of ion beam analytical techniques. The principle underlying all the techniques is that ions at MeV energies are used as projectiles to cause interactions with the target material. Because of the limited range of ions in matter, there is a

Employing validation and verification tests as an integral part of evacuation model development.

The definition of Validation and Verification (V&V) tests for analysing evacuation model capabilities is the object of a large debate among researchers given the lack of an international standard. Four main types of tests have been reported in the literature, 1) component testing, 2) functional verification, 3) qualitative verification and 4) quantitative validation. An important issue relates

The Thrust of Wendtian Constructivism

The core of Alexander Wendt’s theorization of international politics consists in his intellectual endeavour to develop a theory of the international system as a “social construction,” which lies in stark contrast to the positivist and materialist conceptions of IR as theorized particularly by realists and liberalists. In fact, it is an originally “cultural” theory of international politics explain

Protein-based capacitive biosensors for the detection of heavy-metal ions

Some metal ions, such as copper and zinc, are essential nutrients and catalysts in biochemical reactions. Other metal ions, e.g. cadmium and mercury, are highly toxic elements. Heavy metals detection has proven difficult with classical as well as experimental analytical methods. Novel techniques are required for the measurement of bioavailable toxic elements and for detecting small ligands binding