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An Integrated Technique for Test Vector Selection and Test Scheduling under Test Time Constraint

The quality of test is highly related to the number of faults that can be detected during the testing (fault coverage) and the defect probability of each testable unit. High test quality is reached by applying an excessive number of good test vectors, however, such a high test data volume can be problematic to fit in the ATE's (automatic test equipment) limited memory. We therefore propose, for co

Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2

Popular Abstract in Swedish I hjärnan finns många olika typer av nervceller. De använder sig av olika signalsubstanser, kallade neurotransmittorer, för att kommunicera med andra nervceller. En viss typ av nervceller använder neurotransmittorn dopamin. Dopaminceller finns på många ställen i hjärnan men de flesta ligger i mellanhjärnan i ett par olika cellgrupper som var och en skickar signaler tillParkinsons disease (PD) is a neurodegenerative disorder where dopaminergic neurons of the substantia nigra (SNc) in the mesencephalon are progressively eliminated. The ensuing loss of dopaminergic innervation of the basal ganglia manifests itself as severe motor deficits in PD patients. Clinical trials have shown that cell replacement therapy, where dopaminergic neuroblasts derived from fetal vent

Pathophysiology of bone metastases in prostate cancer

Objective: Men with advanced prostate cancer are at high risk for bone metastases that result in significant skeletal morbidity. This review discusses the pathophysiology of bone metastases in prostate cancer. Methods: Relevant information was identified through searches of published studies, abstracts from scientific meetings, and review articles. Results: Bone metastases are common in patients w

Assessment of Functional Outcome in a National Quality Register for Acute Stroke. Can Simple Self-Reported Items Be Transformed Into the modified Rankin Scale?

Background and Purpose-To enable self-reporting of functional outcome in quality registers, the corresponding questions have to be easy to interpret. In scientific research, the modified Rankin Scale (mRS) is a standard assessment method. Such methods, with an outsider observer, are not feasible to use in quality registers. For several aspects, eg, comparisons between outcome in clinical studies a

Positional cloning of ncf1- a piece in the puzzle of arthritis genetics.

Positional cloning of susceptibility genes in complex diseases like rheumatoid arthritis in humans is hampered by aspects like genetic heterogeneity and environmental variations, while genetic studies in animal models contain several advantages. With animal models, the environment can be controlled, the genetic complexity of the disease is minimized and the disease onset can be predicted, which si

Median nerve latency measurement agreement between portable and conventional methods

A portable nerve conduction testing device was compared with a conventional method of measuring median nerve distal latencies. In a population-based study, a health questionnaire was mailed to a random sample of 3000 participants (aged 25 to 74 years). Two hundred and sixty-two responders with numbness and/or tingling in the median nerve distribution, and 125 asymptomatic responders underwent clin

Time-lapse resistivity investigations for imaging saltwater transport in glaciofluvial deposits

Five intersecting resistivity sections have been measured in glaciofluvial deposits hosting an aquifer of regional importance situated along a heavy traffic highway in Sweden. The winter salt spreading has caused a regular salinity increase through the years. For imaging the transport of saltwater in the aquifer, the sections were measured exactly in the same location before and after winter, and

Bovine anti-Helicobacter pylori antibodies for oral immunotherapy

Background: Passive immunization with orally administered antibodies against specific pathogens has previously been successfully used therapeutically in both animal and human studies. We employed a similar strategy for experimental treatment of mice infected with the gastric pathogen Helicobacter pylori. Methods: An anti-H. pylori bovine colostral hyperimmune immunoglobulin preparation (BIC) was g

Signatures of SN Ia in the galactic thick disk. Observational evidence from alpha -elements in 67 dwarf stars in the solar neighbourhood

We present the first results of a larger study into the stellarabundances and chemical trends in long-lived dwarf stars in the solarneighbourhood that belong to (based on their kinematics) the thin andthick galactic disk, respectively. We confirm that the trends of alpha-elements in the thin and thick disk are distinct (this has previouslybeen shown for Mg by Fuhrmann cite{Fuhrmann}, but e.g. Chen

Pooling reputations

It is shown that there are economics of scope in carrying a reputation, providing a rationale for multi-product firms in the absence of technological or organisational economies. It is also shown that a reputation for producing high quality of an old good may be necessary to introduce and maintain the production of a new good. (C) 2002 Elsevier Science B.V. All rights reserved.

Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases

Tec family protein tyrosine kinases (TFKs) play a central role in hematopoietic cellular signaling. Initial activation takes place through specific tyrosine phosphorylation situated in the activation loop. Further activation occurs within the SH3 domain via a transphosphorylation mechanism, which for Bruton's tyrosine kinase (Btk) affects tyrosine 223. We found that TFKs phosphorylate preferential

Essays on Fiscal Policy, Public Debt and Financial Development

Popular Abstract in Swedish Denna avhandling består av tre olika artiklar som kan läsas separat. Varje artikel har tilldelats ett eget kapitel i avhandlingen. Självständigheten av dessa kapitel bör inte tolkas som att de inte hör ihop. Förutom att alla tillhör området makroekonomi, har alla den gemensamma egenskapen att relatera till nutida ekonomisk politiska debatten. Titeln på den första artikThis thesis consists of three distinct articles that can be read separately. Each one has been awarded a chapter of its own. The independence of these chapters should not be taken as meaning that they are unrelated. Besides belonging all to the subfield of macroeconomics, they share the common feature of being inherently economic policy oriented. The title of the first article is "Fiscal Policy a

In Vitro Activity of Lipopeptides Pal-Lys-Lys-NH2 and Pal-Lys-Lys Alone and in Combination with Antimicrobial Agents against Multiresistant Gram-positive Cocci.

The in vitro activities of the lipopeptides pahnitoyl (Pal)-Lys-Lys-NH2 and Pal-Lys-Lys against gram-positive cocci were investigated. Enterococci and streptococci demonstrated higher susceptibilities than staphylococci and Rhodococcus equi. A positive interaction was shown when the lipopeptides were combined with beta-lactams and vancomycin. These results suggest that lipopeptides are promising c

Hereditary dyslipidemias and combined risk factors in children with a family history of premature coronary artery disease

AIM: Schoolchildren aged 10-11 with a family history of premature coronary artery disease (CAD), were examined in order to identify children with genetically determined dyslipidemias and a combination of risk factors. METHODS: A total of 4000 questionnaires were distributed by the school; 55% of the families answered and returned the questionnaire. Blood lipids, apolipoprotein B, and Lp(a) lipopro

Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis

The growth arrest-specific gene 6 product (Gas6) is a secreted protein related to the anticoagulant protein S but its role in hemostasis is unknown. Here we show that inactivation of the Gas6 gene prevented venous and arterial thrombosis in mice, and protected against fatal collagen/epinephrine-induced thrombo embolism. Gas6-/- mice did not, however, suffer spontaneous bleeding and had normal blee