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Search for new particles in final states with a boosted top quark and missing transverse momentum in proton-proton collisions at s = 13 TeV with the ATLAS detector

A search for events with one top quark and missing transverse momentum in the final state is presented. The fully hadronic decay of the top quark is explored by selecting events with a reconstructed boosted top-quark topology produced in association with large missing transverse momentum. The analysis uses 139 fb−1 of proton-proton collision data at a centre-of-mass energy of s = 13 TeV recorded d

Long-term Mortality and Hospital Readmissions Among Survivors of Sepsis in Sweden : A Population-Based Cohort Study

Background. Survivors of sepsis may experience long-term risk of increased morbidity and mortality, but estimations of cause-specific effects beyond 1 year after a sepsis episode are lacking. Method. This nationwide population-based cohort study linked data from national registers to compare patients aged ≥18 years in Sweden admitted to an intensive care unit from 2008 to 2019 with severe communit

Learning Flame Evolution Operator under Hybrid Darrieus Landau and Diffusive Thermal Instability

Recent advancements in the integration of artificial intelligence (AI) and machine learning (ML) with physical sciences have led to significant progress in addressing complex phenomena governed by nonlinear partial differential equations (PDEs). This paper explores the application of novel operator learning methodologies to unravel the intricate dynamics of flame instability, particularly focusing

Substance use-related problems in mild intellectual disability : A Swedish nationwide population-based cohort study with sibling comparison

Background: Evidence for substance use-related problems in individuals with mild intellectual disability is sparse and mainly limited to selected psychiatric populations. We evaluated the risk of substance use-related problems in individuals with mild intellectual disability compared to the general population. Additionally, we have performed secondary sibling comparison analyses to account for fam

Performance Analysis of Centrifugal Compressor Stage using Detailed Component Level Measurements

This paper deals with the component level breakdown of performance characteristics of a centrifugal compressor using detailed measurements. The compressor stage used for Heavy-Duty applications consisting of the impeller, vaneless diffuser, and volute has been experimentally tested in a gas stand. Several static pressure measurements combined with total pressure and temperature measurements on the

Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney

Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed. Results Overall, 88 ESH-ECS representa

Long-term Quality of Life After Surgery for Mid- and High Rectal Cancer : Hartmann’s Procedure Versus Anterior Resection and Abdominoperineal Resection

Background/Aim: Anterior resection is the gold standard surgery for high and middle rectal tumors. In cases where anterior resection is not feasible, the surgeon resorts to a non-restorative approach such as Hartmann’s procedure or abdominoperineal resection. It is not well studied how Hartmann’s procedure impacts quality of life. This cross-sectional cohort study compares the long-term quality of

Can Urinary Bladder Innervation Be Restored After Outlet Obstruction and Denervation?

Transurethral resection of the prostate, or other methods to decrease outlet resistance usually leads to relief of symptoms in patients with bladder outlet obstruction (BOO). If symptoms of underactivity persist after normalization of outflow conditions, treatment options are limited. In this review, we hypothesize, based on results from basic research, what might become treatment options for such

Generating gravitational waveform libraries of exotic compact binaries with deep learning

Current gravitational wave (GW) detections rely on the existence of libraries of theoretical waveforms. Consequently, finding new physics with GWs requires libraries of nonstandard models, which are computationally demanding. We discuss how deep learning frameworks can be used to generate new waveforms "learned"from a simulation dataset obtained, say, from numerical relativity simulations. Concret

Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model

INTRODUCTION: Tau-positron emission tomography (PET) outcome data of patients with Alzheimer's disease (AD) cannot currently be meaningfully compared or combined when different tracers are used due to differences in tracer properties, instrumentation, and methods of analysis. METHODS: Using head-to-head data from five cohorts with tau PET radiotracers designed to target tau deposition in AD, we te

Knockout of key matrix components and characterization of their phenotypic effect in Stenotrophonomas maltophilia

Biofilms are intricate bacterial communities prevalent in diverse environments and rely on complex physiological adaptations and interactions to manifest community-intrinsic properties. The biofilm matrix itself is a major contributor to biofilm dynamics, as one of the mediators of the interactions within the biofilm, and it is composed of a diverse array of molecules. This project focuses on Sten

IMAGE BASED FEATURE EXTRACTION TO IMPROVE SURVIVAL ANALYSIS IN HEAD AND NECK CANCER

In this thesis we performed a pooled cohort study to investigate the role of radiomics in head and neck cancer prognosis. The aim was to investigate prognostic value for overall survival and cancer recurrence of radiomics combined with previously studied demographic and clinical risk factors. Radiomics features were extracted from the gross tumor volume on a computed tomography captured prior to r

Tailored Dose-Dense Versus Standard Adjuvant Chemotherapy for High-Risk Early Breast Cancer: End-of-Study Results of the Randomized PANTHER Trial

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has

Self adaptive numerical methods with reinforcement learning

To find approximate solutions to initial value problems (IVPs) one can use a wide range of numerical methods. A special group of IVPs referred to as stiff, can be numerically solved by a chain of methods, beginning with an implicit method then Newton's method and last, General minimal residual (GMRES). For GMRES to be more time-efficient, we need to apply a preconditioner to the system of equa

Body mass index and risk of over 100 cancer forms and subtypes in 4.1 million individuals in Sweden : the Obesity and Disease Development Sweden (ODDS) pooled cohort study

BACKGROUND: Obesity, assessed by body mass index (BMI), is an established risk factor for 13 cancers. We aimed to identify further potential obesity-related cancers and to quantify their association with BMI relative to that of established obesity-related cancers.METHODS: Using Cox regression models on 4,142,349 individuals in Sweden (mean age 27.1 years at weight measurement), we calculated hazar