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Numerical simulations of flow structure and turbulent heat transfer in a square ribbed channel with varying rib pitch ratio

In the fast development of advanced gas turbines with increasing output power, the inlet temperature is accordingly increased. Traditional cooling techniques failed to deal with such situations; however, new cooling techniques incorporating ribbed microchannels with higher capability of heat removal are required. In the present research, a square ribbed channel with various rib pitch ratios is des

Resistance to activated protein C, highly prevalent amongst users of oral contraceptives with venous thromboembolism

OBJECTIVE: Inherited resistance to activated protein C (APC resistance), which is caused by a single point mutation in the factor V gene, is a frequent risk factor for venous thromboembolism. The aim of this study was to determine the prevalence of APC resistance and other coagulation disorders in fertile women with venous thromboembolism and also the risk factors these women had been exposed to i

Feedback for increased robustness of forwarding graphs in the cloud

Cloud computing technology provides the means to share physical resources among multiple users and data center tenants by exposing them as virtual resources. There is a strong industrial drive to use similar technology and concepts to provide timing sensitive services. One such domain is a chain of connected virtual network functions. This allows the capacity of each function to be scaled up and d

Enhanced extraction of flavonoids from Odontonema strictum leaves with antioxidant activity using supercritical carbon dioxide fluid combined with ethanol

Flavonoids were extracted from Odontonema strictum leaves by supercritical carbon dioxide, with ethanol. The effect of three independents variables (time, pressure and temperature) on the Total Flavonoid Content (TFC) were optimized by factorial investigation. The TFC and flavonoid recovery varies respectively from 99.33 to 247.78 mg/g of dried extract and 10.68–18.92 mg/g of dried leaves powder,

Liquid-liquid flow patterns and slug hydrodynamics in square microchannels of cross-shaped junctions

Flow patterns for water-butanol, water-toluene, water-hexane, water-oil and water/glycerol (weight ratio 60:40) mixture-oil two-phase flows were visualized in the cross-shaped junctions of three square glass microchannels with hydraulic diameters of 200 µm, 400 µm and 600 µm. The aqueous phase is the continuous phase contacting the channel walls while the organic phase is the dispersed phase in th

Bi-directional algebraic graphic statics

A pre-existing algebraic graphic statics method is extended to allow for interactive manipulations of the force diagram, from which an updated form diagram is determined. Newton's method is used to solve a set of non-linear equations, and the required Jacobian matrix is derived. Additional geometric constraints on the form diagram are introduced, and methods for improving the robustness of the met

Organic phosphorus in the terrestrial environment : a perspective on the state of the art and future priorities

Background: The dynamics of phosphorus (P) in the environment is important for regulating nutrient cycles in natural and managed ecosystems and an integral part in assessing biological resilience against environmental change. Organic P (Po) compounds play key roles in biological and ecosystems function in the terrestrial environment being critical to cell function, growth and reproduction. Scope:

Using Bayes Factors to Test Hypotheses in Developmental Research

This article discusses the concept of Bayes factors as inferential tools that can serve as an alternative to null hypothesis significance testing in the day-to-day work of developmental researchers. A Bayes factor indicates the degree to which data observed should increase (or decrease) the credibility of one hypothesis in comparison to another. Bayes factor analyses can be used to compare many ty

Vulnerability as a Key Concept in Museum Pedagogy on Difficult Matters

In recent years there has been an increasing interest in museum studies in exhibitions on what is termed Difficult Matters (Silvén and Björklund 2006)—such as rape and mass murder—and how such exhibitions may evoke ethical change. This raises the question about the conditions on which such exhibitions can lead to an ethical change. By developing a conceptual framework this article contributes to m

Influence of salinomycin treatment on division and movement of individual cancer cells cultured in normoxia or hypoxia evaluated with time-lapse digital holographic microscopy

Most studies on new cancer drugs are based on population-derived data, where the absence of response of a small population may pass unnoticed. Thus, individual longitudinal tracking of cells is important for the future development of efficient cancer treatments. We have used digital holographic microscopy to track individual JIMT-1 human breast cancer cells and L929 mouse fibroblast cultivated in

Impaired Cerebellar Maturation, Growth Restriction, and Circulating Insulin-Like Growth Factor 1 in Preterm Rabbit Pups

Cerebellar growth is impeded following very preterm birth in human infants and the observed reduction in cerebellar volume is associated with neurodevelopmental impairment. Decreased levels of circulating insulin-like growth factor 1 (IGF-1) are associated with decreased cerebellar volume. The relationship between preterm birth, circulating IGF-1, and key cell populations supporting cerebellar pro