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National Pre-Authorisation Schemes to Ensure Public Health - Scientific Uncertainty, National Policy Choices, and the Risk of Bias

Scientific uncertainty is clearly a prominent hurdle in public health policy and the policy choices made to tackle this uncertainty are largely left to the Member States. Indeed, the Court of Justice of the EU has long since held that the health and the life of humans rank first among the interests that Member States can legitimately pursue - even if they restrict the market freedoms in doing so -

From borophene polymorphs towards a single honeycomb borophane phase : reduction of hexagonal boron layers on Al(111)

The recent interest in characterizing 2D boron polymorphs has led to claims of the first stabilization of a honeycomb phase with conical Dirac-like electron dispersion. However, the synthesis of chemically stable, single, and homogeneous 2D boron phases still represents a significant experimental challenge. This is ascribed to the intrinsic boron electronic configuration that, at variance with car

Power and rent-seeking in the second homes tourism market : evidence from selected villages in Iran

Numerous studies have examined the challenges associated with developing second-home (SH) tourism in rural areas. However, little attention has been given to exploring the influence of power dynamics and rent-seeking behavior on the Real Estate Market for second homes (SHs). To address this research gap, our study conducted face-to-face interviews with key stakeholders in five selected villages in

Scaling Performance Parameters of Reciprocating Engines for Sustainable Energy System Optimization Modelling

The increased share of variable renewable energy sources such as wind and solar power poses constraints on the stability of the grid and the security of supply due to the imbalance between electricity production and demand. Chemical storage or power-to-X technologies can provide the flexibility that is needed to overcome this issue. To quantify the needs of such storage systems, energy system opti

Lessons learned about openness : EndNote course as an open learning resource

Background: In a workshop about working with the Canvas learning platform, three librarians at Lund University started a project to create a resource for the reference management program EndNote. We started in January 2020 and launched our Canvas course with EndNote X9 in August 2020. In 2021, the entire course was updated to adapt to EndNote 20 and we also added an English version due to request.

Secondary malignancies among mantle cell lymphoma patients

Purpose: With modern treatments, mantle cell lymphoma (MCL) patients more frequently experience long-lasting remission resulting in a growing population of long-term survivors. Follow-up care includes identification and management of treatment-related late-effects, such as secondary malignancies (SM). We conducted a population-based study to describe the burden of SM in MCL patients. Methods: All

Scoping carbon dioxide removal options for Germany–What is their potential contribution to Net-Zero CO2?

In its latest assessment report the IPCC stresses the need for carbon dioxide removal (CDR) to counterbalance residual emissions to achieve net zero carbon dioxide or greenhouse gas emissions. There are currently a wide variety of CDR measures available. Their potential and feasibility, however, depends on context specific conditions, as among others biophysical site characteristics, or availabili

Looking back to move forwards: A social and cultural history of home heating (JUSTHEAT) : Interim findings from the first round of case studies

This short report is one of a series of outputs to flow from the international,interdisciplinary project ‘Looking back to move forwards: a social and cultural historyof home heating’ (JUSTHEAT), funded through the Collaboration of Humanities andSocial Sciences in Europe (CHANSE) initiative, which began in 2022 and runs until2025. Within this project, we aim to understand how major changes to home

Examining the validity of the Mini-Mental State Examination (MMSE) and its domains using network analysis

BackgroundThe Mini-Mental State Examination (MMSE) is the most widely used standardised screener for impairments across a range of cognitive domains. However, the degree to which its domains (orientation, registration, attention, recall, language, and visuospatial) capture cognitive functioning measured using standardised neuropsychological tests is unclear.MethodA longitudinal research design wit

Big Five of Mindfulness and Personality: Cross-Cultural Network Analysis

ObjectivesResearch on personality seeks to understand what makes people similar or distinct from another. However, there is still a limited understanding of processes that underpin an individual’s personality, such as interactions with other psychological dispositions such as trait mindfulness. Elucidating the unique relationships between mindfulness and personality traits with network analysis ca

Unique contributions of anxiety, stress and depression to immunity: A cross-cultural investigation

While immunity and psychological distress are strongly associated, studies seldom consider how different types of distress relate to immune functioning. The literature tends to emphasis the impact of stress on immunity. The present cross-sectional study estimated the unique contributions of depression, anxiety, and stress on immune function in culturally diverse samples of adults from Italy, New Z

Alterations in attentional processing in youth with misophonia: A phenotypical cross-comparison with anxiety patients

BackgroundMisophonia is a complex condition characterized by extreme emotional distress in response to specific sounds or specific visual stimuli. Despite a growing body of clinical and neuroscientific literature, the etiology of this condition remains unclear. Hyperarousal, that is, a state of heightened alertness and disinhibition, as a core feature of misophonia is supported by behavioral and n

Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis

BackgroundCognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as In

Stabilizing Translucencies : Governing AI transparency by standardization

Standards are put forward as important means to turn the ideals of ethical and responsible artificial intelligence into practice. One principle targeted for standardization is transparency. This article attends to the tension between standardization and transparency, by combining a theoretical exploration of these concepts with an empirical analysis of standardizations of artificial intelligence t

Primary perianal Paget’s disease: three cases

Perianal Paget’s disease (PPD) is a rare intraepidermal neoplastic disease, presenting with nonspecific symptoms, such as pruritis ani or eczema. Perianal Paget’s disease may present as a primary lesion or as a paramalignant phenomenon. Uniform evidence-based treatment strategies have not been defined for this rare condition, and currently, different treatment methods are suggested. This case repo

Study of scintillation properties and performance of CsI(Tl) detectors over time

This work presents a systematic study of the properties (Light Output Non-Uniformity (LONU) and energy resolution) of two CsI(Tl) scintillation units over a span of almost three years, under adverse conditions of humidity and temperature. These two crystals are part of the CALIFA detector, a highly segmented calorimeter and spectrometer for γ rays and light-charged particles, that is placed surrou