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It's Part of Me, Not All of Me : Young Women's Experiences of Receiving a Diagnosis Related to Diverse Sex Development

Study Objective: To understand young women's experiences of receiving a diagnosis related to diverse sex development.Design: A qualitative narrative analysis of interviews.Setting: Karolinska University Hospital.Participants: Nine women (aged 20-26 years) with complete androgen insensitivity syndrome, XY or XX gonadal dysgenesis.Interventions: Semistructured interviews.Main Outcome Measures: A nar

From knowing nothing to knowing what, how and now : Parents' experiences of caring for their children with Congenital Adrenal Hyperplasia.

Objective This study investigates various kinds of knowing that European parents use when caring for their children with congenital adrenal hyperplasia (CAH). Methods Semi-structured qualitative interviews with 20 parents of 22 children with CAH. Results Parents emphasized the importance of knowing what CAH is and what support their child needs, but also knowing how to cope and make sense of the n

Subdividing the Holocene Series/Epoch : formalization of stages/ages and subseries/subepochs, and designation of GSSPs and auxiliary stratotypes

The Holocene, which currently spans ~11 700 years, is the shortest series/epoch within the geological time scale (GTS), yet it contains a rich archive of evidence in stratigraphical contexts that are frequently continuous and often preserved at high levels of resolution. On 14 June 2018, the Executive Committee of the International Union of Geological Sciences formally ratified a proposal to subdi

Land-use planning for sustainable urban development in africa : A spatial and multi-objective optimization approach

Land-use planning, which requires finding a balance among different conflicting social, economic and environment factors, is a complex task needed everywhere, including Africa. One example is the city of Zanzibar in Tanzania, which is under special consideration for land-use revision. From one side, the city has high potentials for tourist industry and at the other side there are major challenges

Quantitative determination of islet cell surface antibodies using 125I-protein A

A quantitative method to measure islet cell surface antibodies in human patients has been developed using 125I-protein A. Isolated, dispersed, viable rat islet cells prepared by collagenase digestion were fixed in 4% paraformaldehyde to allow storage for up to 7 wk at 4°C. Human sera, heat inactivated and adsorbed with rat liver and kidney powder (100 mg/ml), were incubated with the fixed cells (5

Measurement of jet radial profiles in Pb–Pb collisions at sNN=2.76 TeV

The jet radial structure and particle transverse momentum (pT) composition within jets are presented in centrality-selected Pb–Pb collisions at sNN=2.76 TeV. Track-based jets, which are also called charged jets, were reconstructed with a resolution parameter of R=0.3 at midrapidity |ηch jet|

Real time MRI to elucidate the functionality of coating films intended for modified release

Polymer films based on mixtures of ethyl cellulose (EC) and hydroxypropyl cellulose (HPC) have been widely used to coat pellets and tablets to modify the release profile of drugs. For three different EC/HPC films we used 1H and 19F MRI in combination with a designed release cell to monitor the drug, polymer and water in 5 dimensional (5D) datasets; three spatial, one diffusion or relaxation and a

Measurement of prompt photon production in sNN=8.16 TeV p + Pb collisions with ATLAS

The inclusive production rates of isolated, prompt photons in p+Pb collisions at sNN=8.16 TeV are studied with the ATLAS detector at the Large Hadron Collider using a dataset with an integrated luminosity of 165 nb−1 recorded in 2016. The cross-section and nuclear modification factor RpPb are measured as a function of photon transverse energy from 20 GeV to 550 GeV and in three nucleon–nucleon cen

Radiographers’ perspectives’ on Visual Grading Analysis as a scientific method to evaluate image quality

Introduction: Radiographers routinely undertake many initiatives to balance image quality with radiation dose (optimisation). For optimisation studies to be successful image quality needs to be carefully evaluated. Purpose was to 1) discuss the strengths and limitations of a Visual Grading Analysis (VGA) method for image quality evaluation and 2) to outline the method from a radiographer's perspec

Investigation of autofluorescence in zooplankton for use in classification of larval salmon lice

We present autofluorescence of six zooplankton species, including salmon lice (Lepeophtheirus salmonis), for the purpose of classification in marine environments. Using a 410 nm excitation wavelength, we find that all measured zooplankton species exhibit broad cyan fluorescence centered around 510–520 nm. Furthermore, salmon lice show an absence of red fluorescence from undigested chlorophyll, whi

Animal Signals : Dirty Dancing in the Dark?

The use of highly visible body colours as signals during courtship is well known from animals active in brighter light. Now a sexually dimorphic colouration signal has been discovered in a nocturnal moth, suggesting that visual courtship rituals might even occur at night.

Incidence of Intraocular Lens Exchange after Cataract Surgery

Intraocular lens (IOL) exchange after cataract surgery is unusual but may be associated with suboptimal visual outcome. The incidence of IOL exchange has not been consistently estimated. Such information is invaluable when counseling patients prior to cataract surgery. We examined the incidence of, and indications and risk factors for, IOL exchange after cataract surgery. We also assessed visual o

New approaches to therapy and diagnosis of diabetes

Not only has recombinant DNA added another source of insulin for treatment, but also, and perhaps more important, it has allowed the development of new techniques for studying the structure and function of the B cell at the gene level. We can only hope that this information will bring us closer to the understanding of the disease, so the diabetic patient may benefit from other measures of treatmen

Autoimmunity in insulin-dependent diabetes mellitus

Genetic susceptibility, environmental factors and immune mechanisms are implicated in the pathogenesis and etiology of insulindependent diabetes mellitus. The onset of the disease is associated with a major loss of beta cells, and inflammatory cells may be seen in and around the islets of Langerhans. Insulin-dependent diabetes is often associated with autoimmune endocrinopathies. Antipancreatic ce