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Towards visual strategic communications : an innovative interdisciplinary perspective on visual dimensions within the strategic communications field

The purpose of this paper is to explore how a visual perspective can be applied to strategic communication research. First, the term visual communication will be examined from various perspectives with an attempt to develop a foundation for this new academic territory. Second, this study summarises how visual approaches are applied in strategic communication research during 2005-2015, this is donePurposeThe purpose of this paper is to explore how a visual perspective can be applied to strategic communication research. First, the term visual communication will be examined from various perspectives with an attempt to develop a foundation for this new academic territory. Second, this study summarises how visual approaches are applied in strategic communication research during 2005-2015, this

The Role of Phytonutrient Kaempferol in the Prevention of Gastrointestinal Cancers : Recent Trends and Future Perspectives

In recent years, kaempferol, a natural flavonoid present in various fruits and vegetables, has received significant attention in gastrointestinal cancer research due to its varied therapeutic effects. Kaempferol has been proven to alter several molecular mechanisms and pathways, such as the PI3/Akt, mTOR, and Erk/MAPK pathway involved in cancer progression, showing its inhibitory effects on cell p

EADV Task Force Pruritus White Paper on chronic pruritus and chronic prurigo : Current challenges and future solutions

Chronic pruritus (CP) is frequent in general medicine and the most common complaint in general dermatology. The prevalence of CP is expected to rise in the future due to the ageing population. The clinical presentation, underlying aetiology and treatment strategy of CP are heterogeneous. Also, individual treatment aims and physical, psychic and economic burdens of patients might vary. Chronic prur

Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration

We previously showed that SerpinE2 and the serine protease HtrA1 modulate fibro-blast growth factor (FGF) signaling in germ layer specification and head-to-tail development of Xenopus embryos. Here, we present an extracellular proteolytic mechanism involving this serpin-protease system in the developing neural crest (NC). Knockdown of SerpinE2 by injected antisense morpholino oligonucleotides did

Pooled Population Pharmacokinetic Analysis and Dose Recommendations for Ciprofloxacin in Intensive Care Unit Patients with Obesity

Recent studies have explored the influence of obesity and critical illness on ciprofloxacin pharmacokinetics. However, variation across the subpopulation of individuals with obesity admitted to the intensive care unit (ICU) with varying renal function remains unexamined. This study aims to characterize ciprofloxacin pharmacokinetics in ICU patients with obesity and provide dose recommendations for

Intercomparison of eddy-covariance software for urban tall-tower sites

Long-term tall-tower eddy-covariance (EC) measurements have been recently established in three European pilot cities as part of the ICOS-Cities project. We conducted a comparison of EC software to ensure a reliable generation of interoperable flux estimates, which is the prerequisite for avoiding methodological biases and improving the comparability of the results. We analyzed datasets covering 5

Experimental grazer exclusion increases pollination reliability and influences pollinator-mediated plant-plant interactions in tibetan alpine meadows

1. Co-flowering plant species often interact through shared pollinators, with effects ranging from positive (facilitation) to negative (competition). It remains unclear how this variation relates to variation in floral density, floral trait distinctiveness, and local environmental conditions. We studied the effect of grazer exclusion, a proposed local management strategy, on pollinator-mediated pl

Predictive factors for recurrent acute appendicitis after conservative treatment

AbstractIntroductionConservative treatment of acute appendicitis is gaining popularity, and identifying patients with a higher risk of recurrence is becoming increasingly important. Previous studies have suggested that older age, male sex, diabetes, appendicolith and abscess formation may be contributing factors, however, results from the adult population are inconsistent.AimThis study aims to ide

Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer

We have previously described a new series of selective and orally available galectin-1 inhibitors resulting in the thiazole-containing glycomimetic GB1490. Here, we show that the introduction of polar substituents to the thiazole ring results in galectin-1-specific compounds with low nM affinities. X-ray structural analysis of a new ligand-galectin-1 complex shows changes in the binding mode and l

Convergence Rates and Fluctuations for the Stokes–Brinkman Equations as Homogenization Limit in Perforated Domains

We study the homogenization of the Dirichlet problem for the Stokes equations in R3 perforated by m spherical particles. We assume the positions and velocities of the particles to be identically and independently distributed random variables. In the critical regime, when the radii of the particles are of order m-1, the homogenization limit u is given as the solution to the Brinkman equations. We p

Increased risk of venous thromboembolism in young and middle-aged individuals with hereditary angioedema : a family study

Hereditary angioedema (HAE) due to C1 inhibitor protein (C1-INH) deficiency was recently shown to be associated with increased risk of venous thromboembolism (VTE). This is the first national family study of HAE with the aim to determine the familial risk of VTE. The Swedish Multi-Generation Register was linked to the Swedish National Patient Register during the period 1964-2018. Only HAE patients

Making professional development flexible : A case study

There seems to be a relentless pressure to move towards more flexible approaches to learning and teaching in higher education, as described by Latchem and Hanna (2002) elsewhere in this issue. To achieve this, academic staff need to have access to professional development opportunities in flexible learning. This case study describes the experience of trying to 'practice what we preach' in terms of