Search results
Filter
Filetype
Your search for "*" yielded 529432 hits
Genetic Risk Prediction of Atrial Fibrillation
BACKGROUND—: Atrial fibrillation (AF) has a substantial genetic basis. Identification of individuals at greatest AF risk could minimize the incidence of cardioembolic stroke. METHODS—: To determine whether genetic data can stratify risk for development of AF, we examined associations between AF genetic risk scores and incident AF in five prospective studies comprising 18,919 individuals of Europea
“GMFM in practice: opportunities, challenges and future- what’s app?”
Recension av Lindberg, Berit - Kvinnor - vakna, våga! : en studie kring pedagogen och samhällsvisionären Honorine Hermelin Grönbech
Functional outcomes 10 years after selective dorsal rhizotomy
The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine model
Background A growing body of literature on Roux-en-Y gastric bypass surgery (RYGB) has generated inconclusive results on the mechanism underlying the beneficial effects on weight loss and glycaemia, partially due to the problems of designing clinical studies with the appropriate controls. Moreover, RYGB is only performed in obese individuals, in whom metabolism is perturbed and not completely unde
Long-term survival of patients with CLL after allogeneic transplantation : A report from the European Society for Blood and Marrow Transplantation
Even with the availability of targeted drugs, allogeneic hematopoietic cell transplantation (allo-HCT) is the only therapy with curative potential for patients with CLL. Cure can be assessed by comparing long-term survival of patients to the matched general population. Using data from 2589 patients who received allo-HCT between 2000 and 2010, we used landmark analyses and methods from relative sur
Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers
More than 20 genetic loci have been associated with risk for Alzheimer’s disease (AD), but reported genome-wide significant loci do not account for all the estimated heritability and provide little information about underlying biological mechanisms. Genetic studies using intermediate quantitative traits such as biomarkers, or endophenotypes, benefit from increased statistical power to identify var
Characterization of histone-related chemical modifications in formalin-fixed paraffin-embedded and fresh-frozen human pancreatic cancer xenografts using LC-MS/MS
Post-translational modifications (PTMs) of histones including acetylation, methylation, and ubiquitination are known to be involved in the epigenetic regulation of gene expression and thus can have an important role in tumorigenesis. A number of PTMs have been linked to pancreatic cancer and are frequently studied as potential targets for cancer therapy or diagnosis. The availability of biobank-st
Introduction : Beyond the History of Ethnic Cleansing in Europe
The drama of prostate cancer diagnostics
Wroclaw Changes in Memory Narratives
Local Memories under the Influence of Europeanization and Globalization : Comparative Remarks and Conclusions
A Selective Biomarker Panel Increases the Reproducibility and the Accuracy in Endometrial Biopsy Diagnosis
Grading and histologic typing of endometrial cancer in biopsy material has a direct impact on the decision to perform lymphadenectomy and/or omentectomy in many cancer centers. Endometrial biopsies are among the most common general surgical pathology specimens. Multiple studies have shown that biopsy diagnosis suffers from a lack of reproducibility. Although many biomarkers have been proposed, non
Eastern Europe, Western Europe, New Europe or Just Europe? : Changes of Identities in Post-Cold War Europe
Shoulder pain after stroke – experiences, consequences in daily life and effects of interventions : a qualitative study
Purpose: To describe experiences of shoulder pain after stroke, how pain affects daily life and perceived effects of interventions. Method: A qualitative interview study including 13 community-dwelling persons (six women; median age 65 years) with persistent shoulder pain after stroke. Results: Three categories emerged from the content analysis. In “Multiple pain characteristics” an insidious pain