Arsenic is highly toxic and a significant threat to human health, but certain bacteria have developed defense mechanisms initiated by AsIII binding to AsIII-sensing proteins of the ArsR family. The transcriptional regulator AfArsR responds to AsIII and SbIII by coordinating the metalloids with three cysteines, located in a short sequence of the same monomer chain. Here, we characterize the binding

The introductory chapter presents the aim, outline, and content of the anthology. First, it describes the dilemmas and challenges that arise in custody disputes, drawing on pre-existing empirical research, discussions among policymakers, and legal scholars. Second, the chapter outlines the child welfare family-law systems of the Nordic countries. It is also argued that the focus on gender equality

En artikel i Sydsvenska dagbladet om användning av Generative AI i designprocessen. I artikeln intervjuas Charlotte Sjödell, avdelningen för industridesign vid LTH, Lunds universitet, samt en student från designprogrammet.

Allegiance is a legal concept that seeks to regulate the duty of fidelity of individuals towards states. A particularity of allegiance is the fact that it has been repeatedly used in treaty provisions, as well as interpretation of rules, in the field of International Humanitarian Law. The fields in which it has been introduced are quite broad, from rules relating to Prisoner of War status, to defi

Road verges can support high densities of flowers and could therefore provide new opportunities for the conservation of flower-visiting insects. One way of optimizing road verges for vascular plant diversity is to adjust mowing regimes, but to date it is unclear how this affects flower-visiting insects. Furthermore, for mobile organisms like wild bees and butterflies, there is a risk that the bene

Melanism, the process of heavier melanin deposition, can interact with climate variation at both micro and macro scales, ultimately influencing color evolution in organisms. While the ecological processes regulating melanin production in relation to climate have been extensively studied, intraspecific variations of melanism are seldom considered. Such scientific gap hampers our understanding of ho

Cardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation. Despite these achievements, acute vascular rejection still presents a challenge for long-term xenograft acceptance and new insights into innate and adaptive immune responses as well as detailed characterizations of signaling pathways are ne

Intervju med Charlotte Sjödell, avdelningen för industridesign vid LTH, Lunds universitet, i Sydsvenska dagbladet med anledning av AI utställning på Southern Sweden Design Days, 2023. I artikeln nämns också boken om form av Charlotte Sjödell med titeln "The Artifact Description Library" och som är gjord med hjälp av Chat GPT.

The processes responsible for the formation of Earth's most conspicuous diversity pattern, the latitudinal diversity gradient (LDG), remain unexplored for many clades in the Tree of Life. Here, we present a densely sampled and dated molecular phylogeny for the most speciose clade of damselflies worldwide (Odonata: Coenagrionoidea) and investigate the role of time, macroevolutionary processes, and

BakgrundLångvarig behandling med opioida läkemedel, här definierat som> 3 månader, på indikation långvarig icke-malign smärta är vanligt förekommande i smärtvården. Vid undersökningar i Lund och Linköping har noterats att ungefär en tredjedel av populationen vid smärtklinikerna exponeras för opioidbehandling, trots avsaknad av evidens och samtidigt väl kända risker med behandlingen. Nedtrappning a

Preclinical transplantations using human neuroepithelial stem (NES) cells in spinal cord injury models have exhibited promising results and demonstrated cell integration and functional improvement in transplanted animals. Previous studies have relied on the generation of research grade cell lines in continuous culture. Using fresh cells presents logistic hurdles for clinical transition regarding t

Evaluating the (Formula presented.) scaling function of elastic proton–proton ((Formula presented.)) collisions from recent TOTEM data at (Formula presented.) TeV and comparing it with the same function of elastic proton–antiproton ((Formula presented.)) data of the D0 collaboration at (Formula presented.) TeV, we find, from this comparison alone, an at least 3.79 (Formula presented.) signal of od

This book invites you to embark on a journey of discovery, where words become the palette for the expression of design. Furthermore, this book extends its utility to individuals working with Al and text-to-image creation. By enhancing the effectiveness of prompts, it empowers Al systems like Stable Diffusion, DALL-E, and MidJourney to produce refined and contextually relevant visual outputs. The t

This article explores the links between intolerance of urban noise and emerging notions of privacy in mid-eighteenth-century Altona, a southern provincial town in the Danish monarchy. It focuses on Johann Peter Willebrand (1719–86), who dealt with urban noise both as Altona’s police director and as an intellectual and author of several influential books on the ideal organization of early modern ci

Background This study aimed to describe the initial treatment of clubfoot deformity in Sweden using a national cohort. Secondarily we aimed to analyse the results of the initial treatment in relation to foot severity and additional diseases. Methods A national register, the Swedish Pediatric Orthopedic Quality Register, was used to extract data on children born with clubfoot in 2016–2019. Children

The interplay between aging and immune system deterioration presents a formidable challenge to human health, especially in the context of a globally aging population. Aging is associated with a decline in the body’s ability to combat infections and an increased risk of various diseases, underlining the importance of rejuvenating the immune system as a strategy for promoting healthier aging. In iss

A healthy working life is fundamental for individuals and society. To date, increasingly research connects the earlier, pre-working life to later working life experiences and beyond, recognizing that a worker’s health and exposure starts before the working life begins. The research, however, often lacks a fundamental understanding of (i) the underlying mechanisms and pathways accounting for differ

BACKGROUND: This study aimed to identify the roles of L-tryptophan (Trp) and its rate-limiting enzymes on the receptivity of bovine endometrial epithelial cells. Real-time PCR was conducted to analyze the differential expression of genes between different groups of bovine endometrial epithelial cells. Western blot was performed to detect Cyclooxygenase-2 (COX2) expression after treatment with Trp