Colipase is excreted as a procolipase, colipase101. It is activated by low concentrations of trypsin, hydrolyzing the N-terminal pentapeptide. With higher concentrations of trypsin or in the presence of Ca2+ a smaller form of colipase containing 85 amino acids, appears. It has glycine as the N-terminal and arginine as the C-terminal amino acid residue and has lost 11 amino acids in the C-terminal

Colipase exists in pancreatic juice in a pro-form which is activated by limited trypsin hydrolysis. During this activation, the N-terminal pentapeptide 1Val-Pro-Asp-Pro-5Arg is cleaved. The new N-terminal sequence formed, 6Gly-Ile-Ile-Ile-10Asn, contains three isoleucine residues. The importance of these for stimulating lipase activity has been investigated by successive Edman degradation of epsil

This study examines a recent reform in the Swedish teaching profession—the so-called first teacher reform, aimed at increasing teacher professionalism and the status of teachers. The reform created a situation by which a new role had to be created and inhabited by first teachers, appointed on what were considered arbitrary criteria. There were few existing norms, rules, and routines to draw upon f

Vilken slags profession är lärarkåren? Är lärarkåren ens en profession? Vad innebär autonomi och hur påverkas en yrkesgrupp av att det uppstår hierarkier inom den? Den här boken, om förstelärarreformens införande i svensk skola, för en nyanserad diskussion av dessa frågor som ytterst handlar om förutsättningarna för lärares yrkesutövning.Författarna visar att förestelärarreformen har stärkt lärarn

This article seeks to develop the recent attention to memory by outlining a hermeneutical approach that links memory closely to philosophical reflections on referentiality, narrativity and temporality. From insights of modern and ancient theories of memory, the the present approach insists that memory is referential in that its images are held to derive from outside memory, that it is narrative in

OBJECTIVES: To determine the genetic background underlying the Pk phenotype in two Thai sisters suffering from multiple spontaneous abortions.BACKGROUND: The P antigen is carried by globoside, an abundant glycosphingolipid in the red blood cell (RBC) membrane. Inactivating mutations in the 3-β-N-acetylgalactosaminyltransferase gene (B3GALNT1) give rise to the rare Pk phenotype, which lack the P an

This study suggests an optimization framework to plan and design a network of bike lanes in an urban context, based on equity principles and subject to a given available budget. The novelty of the proposal consists in an objective function that aims at minimizing the existing inequities among different population groups in terms of accessibility/opportunity to the bikeways. The proposed methodolog