The goal of the HIBEAM/NNBAR program is to search for baryon number violation via the conversion or oscillation of neutrons into sterile neutrons and/or antineutrons at the European Spallation Source. A key experimental component of the program is the construction of an annihilation detector to directly observe the production of an antineutron following the oscillation. Design studies for the anni

Background: One of the challenges of the 21st century is the high turnover rate in the nursing profession due to burnout and mental illness. From a biopsychosocial perspective, an individual's personality is an important vulnerability-resilience factor that comprises four temperament traits (i.e., a person's emotional reactions) and three character traits (i.e., self-regulation systems). Indeed, d

Background: The requirement concerning formal education for emergency medical dispatcher (EMD) is debated and varies, both nationally and internationally. There are few studies on the outcomes of emergency medical dispatching in relation to professional background. This study aimed to compare calls handled by an EMD with and without support by a registered nurse (RN), with respect to priority leve

Recent studies highlight phosphorylated tau (p-tau) at threonine tau 217 (p-tau217) as a new promising plasma biomarker for pathological changes implicated in Alzheimer’s disease (AD), but the specific brain pathological events related to the alteration in p-tau217 plasma levels are still largely unknown. Using immunostaining techniques of postmortem AD brain tissue, we show that p-tau217 is found

The aim of this study is to characterize atrial fibrillatory rate (AFR) extracted from a cohort of continuously monitored atrial fibrillation (AF) patients as function of episode duration and onset time. The f-wave signal used to compute the AFR was extracted from a single lead ECG strip of the AF episodes stored in an Implantable Cardiac Monitor (ICM) in a cohort of 99 patients. The f-wave signal

The atrio-ventricular (AV) node is the primary regulator of ventricular rhythm during atrial fibrillation (AF). Hence, ECG based characterization of AV node properties can be an important tool for monitoring and predicting the effect of rate control drugs. In this work we present a network model of the AV node, and an associated workflow for robust estimation of the model parameters from ECG. The

In a multicentre phase III study of disseminated malignant melanoma performed in Sweden and Norway, 326 patients were randomised to receive treatment with the combination dacarbazine [DTIC] (D) and vindesine (V) with or without the addition of cisplatin (P). D was given intravenously (i.v.) at a dose of 250 mg/m2 days 1-5 every 4 weeks and V was given i.v. at a dose of 3.0 mg/m2 day 1 weekly. P wa

Introduction: Population-based studies about the consequences of SARS-CoV-2 infection (COVID-19) in pregnancy are few and have limited generalizability to the Nordic population and healthcare systems. Material and methods: This study examines pregnant women with COVID-19 in the five Nordic countries. Pregnant women were included if they were admitted to hospital between 1 March and 30 June 2020 an

Aim: Bumetanide, a diuretic agent, that reduces intracellular chloride—thereby reinforcing GABAergic inhibition—has been reported to improve core symptoms of autism in children. Given the positive results reported from French trials of bumetanide in children with autism, we decided to evaluate its effects in a small-scale pilot study, in advance of a larger randomised controlled study (RCT). Metho

Resonant inelastic x-ray scattering spectra excited at the π∗-resonance of the nitrogen molecule are presented. Well-resolved vibrational excitations in the electronic ground state, and in the 3σg-11πg1a1Πg state are observed. The spectra are analyzed within the Kramers-Heisenberg formalism, and the importance of lifetime-vibrational interference effects is highlighted. In addition, strongly disso

In the prospect of realizing bulk superconductivity in a topological insulator, metal-doped Bi2Se3 has been investigated with increased interest, where the Cu-, Sr-, and Nb-doped systems appear particularly promising. It is generally assumed that metal intercalation into the van der Waals (vdW) gap is responsible for the superconductivity. We have investigated the local structure of Nb in samples

Helical edge states of two-dimensional topological insulators show a gap in the density of states (DOS) and suppressed conductance in the presence of ordered magnetic impurities. Here we will consider the dynamical effects on the DOS and transmission when the magnetic impurities are driven periodically. Using the Floquet formalism and Green's functions, the system properties are studied as a funct

Padjelanta nationalpark har en exceptionellt artrik och fort­ farande till stor del okänd lavflora inklusive många sällsynta eller rödlistade arter. Lavforskaren Gunnar Degelius hittade 1941 den rödlistade blylaven på ett klippblock vid fjället Unna Duvgge på sydvästra stranden av Virihaure vilket är den nordligaste lokalen för arten i Sverige. Sommaren 2020 återfann vi blylaven efter 79 långa år,

The Wiedemann–Franz law states that the charge conductance and the electronic contribution to the heat conductance are proportional. This sets stringent constraints on efficiency bounds for thermoelectric applications, which seek a large charge conduction in response to a small heat flow. We present experiments based on a quantum dot formed inside a semiconducting InAs nanowire transistor, in whic

The 30+ unique ligands of the TGFβ family signal by forming complexes using different combinations of type I and type II receptors. Therapeutically, the extracellular domain of a single receptor fused to an Fc molecule can effectively neutralize subsets of ligands. Increased ligand specificity can be accomplished by using the extracellular domains of both the type I and type II receptor to mimic t

Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal disease. The only option for curative treatment is resection of the tumor followed by standard adjuvant chemotherapy. Yet, early relapse due to chemoresistance is almost inevitable. Herein, we delineated the genetic intratumor heterogeneity in resected PDAC, with the aim to identify evolutionary patterns that may be associated with ov

I artikeln studeras spelutvecklares upplevelser av sitt arbete och då särskilt i relation till föreställningar om kreativa och ekonomiska ideal. Artikeln är baserad på en analys av semistrukturerade intervjuer med spelutvecklare i svenska dataspelsbolag. Genom begreppet ’relational work’ belyses spänningen mellan passion för arbetet och dess ekonomiska villkor, och hur gränserna mellan vad som ans

A series of iron(ii) complexes with the general formula [FeII(L2-Qn)(L)]n+ (n = 1, L = F−, Cl−; n = 2, L = NCMe, H2O) have been isolated and characterized. The X-ray crystallographic data reveals that metal–ligand bond distances vary with varying ligand field strengths of the sixth ligand. While the complexes with fluoride, chloride and water as axial ligand are high spin, the acetonitrile-coordin

The Mediterranean Basin has experienced extensive change in geology and climate over the past six million years. Yet, the relative importance of key geological events for the distribution and genetic structure of the Mediterranean fauna remains poorly understood. Here, we use population genomic and phylogenomic analyses to establish the evolutionary history and genetic structure of common wall liz