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Physical Activity Reduces Epilepsy Incidence : a Retrospective Cohort Study in Swedish Cross-Country Skiers and an Experimental Study in Seizure-Prone Synapsin II Knockout Mice

Background: Epilepsy patients commonly exercise less than the general population. Animal studies indicate beneficial effects of physical activity in established epilepsy, while its effect on the development is currently less known. Methods: Here, we investigated the incidence of epilepsy during 20 years in a cohort of participants from the long-distance Swedish cross-country ski race Vasaloppet (n

Four Dimensions of Criticism Against Gender-Fair Language

The gender-neutral third-person pronoun singular hen was recently introduced in Swedish as a complement to she (hon) and he (han). The initiative to add hen initially received strong criticism. In the present study, we analyzed 208 arguments from 168 participants with critical attitudes toward hen. We used Blaubergs’ (1980) and Parks and Roberton’s (1998) taxonomies of critical arguments against p

Experimental and numerical study of natural convection in bottom-heated cylindrical cavity filled with molten salt nanofluids

This paper combines numerical and experimental to study the heat transfer by free convection for nanofluids of molten salt within a cavity with cylindrical shape which is heated at the bottom and releases heat at the top. The aim is to acquire the free convection laws for nanofluids of molten salt in a cylindrical cavity. It is found that after adding nanoparticles, the molten salts have lower vis

Refining the history of Younger Dryas and Early Holocene glacier oscillations in the Borgarfjörður region, western Iceland

The lower Borgarfjörður region, western Iceland, has been central to the reconstructions of the dynamics and collapse of the Icelandic Ice Sheet during the deglaciation. Here, extensive stratigraphical sections and landforms provide a rare opportunity to study past glacier dynamics in this part of Iceland. Previous studies reveal that a large outlet glacier in Borgarfjörður advanced during the Lat

Effect of membrane composition on DivIVA-membrane interaction

DivIVA is a crucial membrane-binding protein that helps to localize other proteins to negatively curved membranes at cellular poles and division septa in Gram-positive bacteria. The N-terminal domain of DivIVA is responsible for membrane binding. However, to which lipids the domain binds or how it recognizes the membrane negative curvature remains elusive. Using computer simulations, we demonstrat

“Mocked by the Archon of Lust” : Panarion 1.26 and Epiphanius’ Hyperboles on Sex and Ascetics Read in Light of Fourth Century Ecclesiastical Debates

This article argues that the depictions of Gnostic sects performing horrendous rites in Epiphanius of Cyprus’ work Panarion worked as rhetorical devices to shift focus away from his own position vis-à-vis marriage, sex, and consumptions of good food and wine, a position that was considered liberal in the context of fourth century eccle- siastical debates. It here is shown how Epiphanius’ descripti

Point of no return : zero philopatry in an otherwise philopatric bird

The return of individual birds to an exact area in successional years is a remarkable phenomenon. Here we report on the remarkably reversed: the complete absence of returning individuals of a migratory passerine with otherwise pronounced philopatry. In Abisko in northern Sweden none of the banded adult willow warblers (Phylloscopus trochilus) returned to breed 2011-14. This is in stark contrast to

Valvular imaging in the era of feature-tracking : A slice-following cardiac MR sequence to measure mitral flow

BACKGROUND: In mitral valve dysfunction, noninvasive measurement of transmitral blood flow is an important clinical examination. Flow imaging of the mitral valve, however, is challenging, since it moves in and out of the image plane during the cardiac cycle.PURPOSE: To more accurately measure mitral flow, a slice-following MRI phase contrast sequence is proposed. This study aimed to implement such

Synthesis, life cycle assessment, and polymerization of a vanillin-based spirocyclic diol toward polyesters with increased glass-transition temperature

Bio-based rigid diols are key building blocks in the development and preparation of high performance bioplastics with improved thermal and dimensional stability. Here, we report on the straightforward two-step synthesis of a diol with a spirocyclic acetal structure, starting from bio-based vanillin and pentaerythritol. According to a preliminary life cycle assessment (LCA), the greenhouse gas emis