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Coulomb excitation of neutron-rich Zn isotopes: First observation of the 2(1)(+) state in Zn-80

Neutron-rich, radioactive Zn isotopes were investigated at the Radioactive Ion Beam facility REX-ISOLDE (CERN) using low-energy Coulomb excitation. The energy of the 2(1)(+) state in Zn-78 could be firmly established and for the first time the 2(+)-> 0(1)(+) transition in Zn-80 was observed at 1492(1) keV. B(E2,2(1)(+)-> 0(1)(+)) values were extracted for Zn-74,Zn-76,Zn-78,Zn-80 and compared to la

Reduced examination time by monocular and bilateral examination in the same session with a new computerized dark adaptometer

To reduce the examination time for dark adaptometry, which including preadaptometry normally takes 30 minutes for an eye, a computerized adaptometer was constructed allowing monocular examination of both eyes simultaneously. The total examination time was thereby reduced from 60 to 30 minutes. This improvement was achieved by the use of electronically monitored transparent shutters that were alter

Optical Doppler tomography for monitoring vascularization during photodynamic therapy of skin cancer lesions

We investigate vascular changes during Photodynamic therapy (PDT) of skin tumors using optical Doppler tomography (ODT). The effect of vascular shut down on tumor destruction is currently not known, and to optimize treatment it is relevant to investigate this issue further. Optical Doppler tomography is capable of measuring blood flow in biological tissue down to 1-2 mm with sub-mm/s velocity sens

Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type I in breast cancer patients

Tumour angiogenesis and the levels of plasminogen activator inhibitor type I (PAI-I) are both informative prognostic markers in breast cancer. In cell cultures and in animal model systems, PAI-I has a proangiogenic effect. To evaluate the interrelationship of angiogenesis and the PAI-I level in breast cancer, we have evaluated the prognostic value of those factors in a total of 228 patients with p

Dynamics of cytoskeletal proteins in developing pine ectomycorrhiza

Mycorrhizal short roots of Pinus contorta Dougl. ex Loud colonized by Suillus variegatus (Sow. ex Fr.) O. Kuntze or Paxillus involutus (Batsch) Fr. were collected 1->60 days after fungal contact. The proteins of the inoculated roots were extracted, electrophoretically separated, blotted and immunostained for alpha-tubulin and actin. The development of the mycorrhiza was also followed microscopical

An investigation of the reaction mechanism for the promotion of propane oxidation over Pt/Al2O3 by SO2

Total oxidation of propane with oxygen in the absence and the respective presence of SO2 in the feed gas was studied over 1 wt% Pt on gamma -Al2O3 using transient experiments with TAP (temporal analysis of products) and in situ DRIFT spectroscopy. The TAP experiments confirm the promoting role of SO2 on the conversion of propane and, moreover, show an inhibiting effect from SO2 on the conversion o

Changes in pore morphology and fluid transport in compressed articular cartilage and the implications for joint lubrication

Cartilage sections were cut from the middle zone of pig knee articular cartilage and attached to substrates in two different kinds of newly designed 'pressure cells', one for fluorescence the other for NMR measurements, The fluorescence cell was filled with buffer solution containing fluorescently marked 70 kDa dextran which was allowed to diffuse into the cartilage pores. A second glass surface w

Enhanced expression of iNOS intratumorally and at the immunization site after immunization with IFNgamma-secreting rat glioma cells

Nitric oxide (NO) can modulate both tumor growth and antitumor immune responses. In order to elucidate the mechanism of curative therapeutic immunization with IFNgamma-producing glioma cells, we examined the expression of inducible nitric oxide synthase (iNOS) in tissue sections from immunized animals. There was a significantly enhanced iNOS expression both intratumorally and at the immunization s

A uniqueness theorem in the inverse spectral theory of a certain higher-order ordinary differential equation using Paley-Wiener methods

The paper examines a higher-order ordinary differential equation of the form P[u]:= Sigma(j,k=0)(m) D(j)a(jk)D(k)u = gimel u, x is an element of [0, b), where D=i(d/dx), and where the coefficients a(jk), j, k is an element of [0,M], with a = 1, satisfy certain regularity conditions and are chosen so that the matrix (a(jk)) is hermitean. It is also assumed that m > 1. More precisely, it is proved,

An Integrated Model of the European Extremely Large Telescope

Integrated models including optics, structures, control systems, and disturbances are important design tools for Extremely Large Telescopes (ELTs). An integrated model has keen formulated for the European ELT and it includes telescope structure, main servos, primary mirror segment control system, wind, optics, wavefront sensor, deformable mirror, and an AO reconstructor and controller. There are t

Assembling ferromagnetic single-electron transistors by atomic force microscopy

We demonstrate the assembly of nanoscale ferromagnetic single-electron transistors using atomic force microscopy for imaging as well as for nanoscale manipulation. A single 30 nm Au disc, forming the central island of the transistor, is manipulated with angstrom precision into the gap between a plasma-oxidized Ni source and drain electrodes. The tunnel resistances can be tuned in real time during

Improvement of the detection of myocardial ischemia thanks to information technologies

Background: The standard 12-lead ECG remains one of the basic investigations for the early detection and assessment of acute coronary syndromes. It is easy to perform, anywhere and anytime, and can be digitally transmitted within minutes to an emergency medical service for remote advice and triage. But the conventional ST-segment deviation criteria are of limited diagnostic accuracy. The purpose o

IL-1 beta induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism

Background: Interleukin 1 beta ( IL- I beta) is found in bronchoalveolar lavage fluids from asthmatic patients and plays an important role in normal immunoregulatory processes but also in pathophysiological inflammatory responses. The present study was designed to investigate if IL- I beta could be involved in the development of airway hyperresponsiveness and if transcriptional mechanisms, epithel

Marker-based relatedness predicts egg-hatching failure in great reed warblers

I examine the relationship between reproductive success and marker-based relatedness (MBR; inferred from variation at 21 microsatellite loci) of pair-mates in a semi-isolated population of great reed warblers (Acrocephalus arundinaceus) over a 12 year period. There was a negative relationship between egg-hatching success and MBR, but no association between MBR and three other components of fitness