Asymmetrisk katalys har under de senaste decennierna utvecklats kraftigt. År 2001 delade Knowles, Noyori och Sharpless Nobelpriset i kemi för sina banbrytande bidrag inom just detta område. Utmaningen idag är att utveckla nya metoder inom asymmetrisk katalys som även tar hänsyn till vår växande miljöpåfrestning. Nästan alla av dagens kirala katalysatorer är utvecklade för syntes i organiska lösnin

The application of Supersoft Decision theory (SSD) to fire safety problems, and of decision analysis in general to decisions involving a high degree of epistemic uncertainty, are discussed. SSD and two traditional decision analytic methods employed earlier within the context of fire engineering are compared, particularly regarding how uncertainties are dealt with and the robustness of decisions –

Abstract in Norwegian Dette oplæg handler om moderniseringen af den indledende matematikundervisning ved de videregående uddannelser. Med henblik på diskussionen fremhæves tre teser og tilhørende konkrete eksempler fra et kursus som bud på, hvad ’modernisering’ omfatter og hvordan den kan realiseres. Fokus her er primært på de uddannelser, hvor den indledende matematikundervisning afholdes som sto

Popular Abstract in Swedish Basala ganglierna ligger under hjärnbarken i hjärnan och består av grupper av nervceller som är förbundna med varandra och med hjärnbarken. Till dessa grupper av nervceller hör striatum, globus pallidus, subthalamicus-kärnan och substantia nigra. Patologiska förändringar i olika delar av basala ganglierna orsakar många av de symptom som kännetecknar Huntington's och ParHuntington's disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia and extensive striatal neuronal death. The mechanism through which the widely expressed mutant huntingtin mediates striatal neurotoxicity is unknown. Excitotoxicity, i.e. calcium-dependent cell death induced by activation of NMDA receptors, has been hypothesized to play an important role in HD. Ou

In this paper projective normalization and projective invariants of planar curves are discussed. It is shown that there exists continuous affine invariants. It is shown that many curves can be projected arbitrarily close to a circle in a strengthened Hausdorff metric. This does not infer any limitations on projective invariants, but it is clear that projective normalization by maximizing compactne

Popular Abstract in Swedish Interndosimetri ur ett makroskopiskt och mikroskopiskt perspektiv Med interndosimetri menas den metod man använder för att bestämma en absorberad dos till en vävnad för ett radioaktivt ämne som är fördelat i kroppen. Absorberad dos, dvs den av strålningen deponerade energin per massenhet, mäts i enheten gray (1 J/kg = 1 Gy) och kan beräknas med ekvationerna som syns påInternal dosimetry deals with the assessment of absorbed dose for radionuclides distributed inside the body. The absorbed dose is in its turn used for correlation with the biological effect caused by the irradiation. In radioimmunotherapy is however the correlation not easily found and factors influencing this are evaluated and discussed in this work. The internal dosimetry could be subdivided int

Popular Abstract in English If you wonder about the journey of goods and services before they reach you and the effects that journey has on the natural environment and the society, this dissertation is for you. In order to deliver goods and services from raw materials to you, the customer/consumer, several organizations and individuals interact with each other. They source the materials, manufactuTo develop sustainable supply chains in a way that their negative environmental and social effects are minimized, shortand long-term targets should be set. The transformation of supply chains towards these targets calls for the development of innovative strategies and the need to continuously identify, classify, and tackle the challenges that can hinder the execution of such strategies. To develop

Cities are both at risk and the cause of risk. The interconnectedness of urban features and systems increases the likelihood of complex disasters and a cascade or ‘domino’ effect from related impacts. However, the lack of research means that our knowledge of urban risk is both scarce and fragmented. This paper presents a framework for understanding and addressing urban risk. It examines the unique