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Acute myelogenous leukemia (AML) is characterized by the accumulation of immature cells due to disturbed differentiation and proliferation of the myeloid lineage. Genetic alterations affecting transcription factors and receptor tyrosine kinases have been identified in AML and causally linked to the disease. The goal of this review is to address the role of the different genetic alterations in self
Using a special gait re-education programme, combining methods in physiotherapy with a psychological therapeutic approach to integrate the prosthesis with normal movements and to increase body awareness, the authors studied unilateral trans-femoral amputees aged 16-60 years with trauma or tumour as causes. In their service area they found 16 such current prosthetic users with at least 2 years of p
A method for simultaneous determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in urine is described. These compounds are metabolites of N-methyl-2-pyrrolidone, a powerful and widely used organic solvent. 5-Hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide were purified from urine by adsorption to a C8 solid-phase extraction column and then elution by ethyl
This note summarizes many detailed physics studies done by the ATLAS and CMSCollab orations for the LHC, concentrating on processes involving the production of high mass states. These studies show that the LHC should be able to elucidate the mechanism of electroweak symmetry breaking and to study a variety of other topics related to physics at the TeV scale. In particular, a Higgs boson with coupl
We set up a structural model to study credit risk for a portfolio containing several or many credit contracts. The model is based on a jump-diffusion process for the risk factors, i.e. for the company assets. We also include correlations between the companies. We discuss that models of this type have much in common with other problems in statistical physics and in the theory of complex systems. We
There is general consensus that children of women with pre-existing diabetes mellitus (PDM) have an increased risk of malformations and neurodevelopmental problems. Whether this is also true for children of women with gestational diabetes mellitus (GDM) is a matter of debate. This study investigated inpatient hospital care up to 10 y of age of children born to GDM and PDM women as a rough estimate
Context. The Si III] 1892 angstrom intercombination line shows an anomalously high intensity in spectra of the radiation-rich Weigelt blobs in the vicinity of Eta Carinae. The line disappears during the 100 days long spectral events occurring every 5.5 years. Aims. The aim is to investigate whether resonance-enhanced two-photon ionization (RETPI) is a plausible excitation mechanism for the Si III]
We studied the prevalence and intensity of the haemosporidian blood parasite Haemoproteus payevskyi in great reed warblers at Lake Kvismaren (6 years) and Lake Segersjo (3 years) in Sweden. Based on microscopic inspection of slides from 282 adult birds, 20.6% showed infection of H. payevskyi in circulating red blood cells in at least 1 year. For parasite prevalence, there was no difference between
ABSTRACT: BACKGROUND: Previous studies on healthy people show that vinegar delays gastric emptying and lowers postprandial blood glucose and insulin levels. The aim of this study was to investigate the effect of apple cider vinegar on delayed gastric emptying rate on diabetes mellitus patients. METHODS: Ten patients with type 1 diabetes and diabetic gastroparesis, including one patient who had und
Previous studies have shown inconsistent associations of folate intake and polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene with gastric cancer risk. Our nested case-control study within the European Prospective Investigation into Cancer and Nutrition cohort is the first prospective study of blood folate levels and gastric cancer. Gastric cancer cases (n = 247) and controls (n
Fifty-six type I diabetic patients with microalbuminuria (albumin excretion rate 20-200 micrograms/min) were characterized as to sex, age, duration of diabetes, smoking habits, blood pressure, glomerular filtration rate, urinary NC1 (the carboxy-terminal domain of collagen IV), and Tamm-Horsfall protein excretion rate. Albumin excretion rate was considered a sign of glomerular damage, NC1 excretio
BACKGROUND: Working as a hairdresser involves exposure to a variety of chemical agents. AIMS: To estimate the risk of such exposure in relation to reproductive outcome. METHODS: A cohort of hairdressers, certified in Sweden from 1970 onwards, and a referent cohort of women from the general population were established and linked to the Swedish Medical Birth Register for the period 1973 to 1994. In
This paper presents a second order continuous-time delta-sigma ADC based on a new feedback DAC technique with the low clock jitter sensitivity of the SC (switched-capacitor) technique and the low peak currents of the SI (switched current) technique. The delta-sigma ADC has been implemented in a 90 nm (1.2 V) RF-CMOS process. It measures 66.4 dB maximum SNR over 1.92 MHz bandwidth with a 312 MHz cl
A generalized Green's function technique for wave propagation of transient fields in one-dimensional media is developed. The medium is partitioned into an arbitrary number of subslabs for which Green operators that map the incident field to the internal fields are defined. Relations between the Green operators for the entire medium and the Green operators for the subslabs are derived. The techniqu
To investigate how an oscillating reaction rate might influence the hydration of cementitious solids, a simple iterative mathematical model that includes recurrent passivation of the surface has been constructed. The algorithm generates a wide variety of hydration curves with a limited number of input parameters: i.e.. V0 (volume of unreacted solid after initial reaction), a, (degree of reaction u
