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Persons and affordances

Interdisciplinary interest in affordances is increasing. This paper is a philosophical contribution. The question is: Do persons offer affordances? Analysis of the concepts ‘person’ and ‘affordance’ supports an affirmative answer. On a widely accepted understanding of what persons are, persons exhibit many of the features typical of socionormative affordances. However, to understand persons as off

The GALAH survey : Scientific motivation

The Galactic Archaeology with HERMES (GALAH) survey is a large high-resolution spectroscopic survey using the newly commissioned High Efficiency and Resolution Multi-Element Spectrograph (HERMES) on the Anglo-Australian Telescope. The HERMES spectrograph provides high-resolution (R ~ 28 000) spectra in four passbands for 392 stars simultaneously over a 2 deg field of view. The goal of the survey i

The GALAH survey : An abundance, age, and kinematic inventory of the solar neighbourhood made with TGAS

The overlap between the spectroscopic Galactic Archaeology with HERMES (GALAH) survey and Gaia provides a high-dimensional chemodynamical space of unprecedented size. We present a first analysis of a subset of this overlap, of 7066 dwarf, turn-off, and sub-giant stars. These stars have spectra from the GALAH survey and high parallax precision from the Gaia DR1 Tycho-Gaia Astrometric Solution. We

The GALAH survey and Gaia DR2 : (non-)existence of five sparse high-latitude open clusters

Sparse open clusters can be found at high galactic latitudes where loosely populated clusters are more easily detected against the lower stellar background. Because most star formation takes place in the thin disc, the observed population of clusters far from the Galactic plane is hard to explain. We combined spectral parameters from the GALAH survey with the Gaia DR2 catalogue to study the dynami

The GALAH Survey : Second data release

The Galactic Archaeology with HERMES (GALAH) survey is a large-scale stellar spectroscopic survey of theMilkyWay, designed to deliver complementary chemical information to a large number of stars covered by the Gaia mission. We present the GALAH second public data release (GALAH DR2) containing 342 682 stars. For these stars, the GALAH collaboration provides stellar parameters and abundances for

The New DSM-5 Impairment Criterion : A Challenge to Early Autism Spectrum Disorder Diagnosis?

The possible effect of the DSM-5 impairment criterion on diagnosing autism spectrum disorder (ASD) in young children was examined in 127 children aged 20-47 months with a DSM-IV-TR clinical consensus diagnosis of ASD. The composite score of the Vineland Adaptive Behavior Scales (VABS) served as a proxy for the DSM-5 impairment criterion. When applying a mild level of impairment (cutoff: 1 SD below

Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers : Application in a Non-US Sample of 1,104 Children

The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, J Autism Dev Disord 42(1):82-93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of the algorithms. The diagnostic validity was lower, with satisfactorily high specificities but modera

Autism spectrum disorders in the Stockholm Youth Cohort : design, prevalence and validity

OBJECTIVE: Reports of rising prevalence of autism spectrum disorders (ASD), along with their profound personal and societal burden, emphasize the need of methodologically sound studies to explore their causes and consequences. We here present the design of a large intergenerational resource for ASD research, along with population-based prevalence estimates of ASD and their diagnostic validity.METH

The Galah Survey : Classification and Diagnostics with t-SNE Reduction of Spectral Information

Galah is an ongoing high-resolution spectroscopic survey with the goal of disentangling the formation history of the Milky Way using the fossil remnants of disrupted star formation sites that are now dispersed around the Galaxy. It is targeting a randomly selected magnitude-limited (V ≤ 14) sample of stars, with the goal of observing one million objects. To date, 300,000 spectra have been obtained

The GALAH survey : Chemical tagging of star clusters and new members in the Pleiades

The technique of chemical tagging uses the elemental abundances of stellar atmospheres to 'reconstruct' chemically homogeneous star clusters that have long since dispersed. The GALAH spectroscopic survey - which aims to observe one million stars using the Anglo- Australian Telescope - allows us to measure up to 30 elements or dimensions in the stellar chemical abundance space, many of which are no

The 2016-2017 peak luminosity of the pre-main sequence variable V2492 Cygni

Context. V2492 Cyg is a young pre-main sequence star presenting repetitive brightness variations of significant amplitude (R - 5 mag) whose physical origin has been ascribed to both extinction (UXor-type) and accretion (EXor-type) variability, although their mutual proportion has not been clarified yet. Recently, V2492 Cyg has reached a level of brightness ever registered in the period of its docu

Removing bias and increasing dynamic range in DREAM flip angle mapping at 7T

DREAM is an ultra-fast multi-slice B1+-mapping technique based on the single-shot STEAM sequence. To study noise and bias related to slice-profiles, DREAM B1+-maps at 3.75 mm resolution were acquired at 7T in phantoms and in human brain with nominal flip angles (FA) between 20° and 90° of the two STEAM preparation pulses. B1+ was decreasing at actual FAs above 50°; noise became apparent at actual

Different populations of CD11b + dendritic cells drive Th2 responses in the small intestine and colon

T-helper 2 (Th2) cell responses defend against parasites. Although dendritic cells (DCs) are vital for the induction of T-cell responses, the DC subpopulations that induce Th2 cells in the intestine are unidentified. Here we show that intestinal Th2 responses against Trichuris muris worms and Schistosoma mansoni eggs do not develop in mice with IRF-4-deficient DCs (IRF-4f/f CD11c-cre). Adoptive tr

Role of CCL25/CCR9 in immune homeostasis and disease

Chemokines constitute a large family of low-molecular-weight proteins (∼10 kDa in size), recognized primarily for their role in directing leukocyte migration under both homeostatic and inflammatory settings. The chemokine CCL25 displays a unique and highly restricted expression pattern compared with other chemokine family members. In the steady state, CCL25 is expressed at high levels primarily in

Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract

Type 1 fimbriae are adhesion organelles expressed by many Gram-negative bacteria. They facilitate adherence to mucosal surfaces and inflammatory cells in vitro, but their contribution to virulence has not been defined. This study presents evidence that type 1 fimbriae increase the virulence of Escherichia coli for the urinary tract by promoting bacterial persistence and enhancing the inflammatory