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Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma : A side reversal by opioid mechanism

Unilateral traumatic brain injury and stroke result in asymmetric postural and motor deficits including contralateral hemiplegia and hemiparesis. In animals, a localized unilateral brain injury recapitulates the human upper motor neuron syndrome in the formation of hindlimb postural asymmetry with contralesional limb flexion and the asymmetry of hindlimb nociceptive withdrawal reflexes. The curren

Predicting the severity of the grass pollen season and the effect of climate change in Northwest Europe

Allergic rhinitis is an inflammation in the nose caused by overreaction of the immune system to allergens in the air. Managing allergic rhinitis symptoms is challenging and requires timely intervention. The following are major questions often posed by those with allergic rhinitis: How should I prepare for the forthcoming season? How will the season's severity develop over the years? No country yet

Unmarried or less-educated patients with mantle cell lymphoma are less likely to undergo a transplant, leading to lower survival

It is unknown how many mantle cell lymphoma (MCL) patients undergo consolidation with autologous hematopoietic cell transplantation (AHCT), and the reasons governing the decision, are also unknown. The prognostic impact of omitting AHCT is also understudied. We identified all MCL patients diagnosed from 2000 to 2014, aged 18 to 65 years, in the Swedish Lymphoma Register. Odds ratios (ORs) and 95%

No Place like Home? Postdeployment Reintegration Challenges Facing South African Peacekeepers

This study focuses on soldiers returning from peacekeeping missions and the challenges they experience adapting to the home environment in the postdeployment phase. The article focuses on South African peacekeepers returning from missions in Darfur/Sudan, the Democratic Republic of Congo, and Burundi. Interviews with 50 South African peacekeepers on the challenges they face in terms of their homec

What’s the ‘added value’ of Male Peacekeepers? (Or why we should stop instrumentalising Female Peacekeepers’ Participation

How realistic and how fair are the expectations that we place on the small minority of female peacekeepers to bring an ‘added value’ to peace operations? Not at all, I argue in this brief, which examines the instrumentalisation of female participation and suggests that it is time to move beyond the question of an ‘added value’ that often translates into ‘added burden’.Both male and female peacekee

Optically Unstable Phase from Ion-Ion Interactions in an Erbium-Doped Crystal

Optical many-body systems naturally possess strong light-matter interactions and are thus of central importance for photonic applications. However, these applications are so far limited within the regime of intrinsic dynamically stable phases, and the possibility of unstable phases remains unidentified. Here we experimentally revealed a new dynamical phase of intrinsic optical instability by using

Pre- and Postoperative Circulating IGF-I, IGFBP-3, and IGFBP-7 Levels in Relation to Endocrine Treatment and Breast Cancer Recurrence : A Nested Case-Control Study

Insulin-like growth factor-I (IGF-I) and its binding proteins (BPs) have been associated with breast cancer risk, especially high IGF-I concentrations and the biologically active fraction estimated as the IGF-I/IGFBP-3 molar ratio. The relation of circulating IGF-I and IGFBP-3 concentrations with risk of breast cancer recurrence has been less documented. In addition a new member to a sub-group of

Induction of interferon-β and interferon signaling by TRAIL and Smac mimetics via caspase-8 in breast cancer cells

Breast cancer prognosis is frequently good but a substantial number of patients suffer from relapse. The death receptor ligand TRAIL can in combination with Smac mimetics induce apoptosis in some luminal-like ER-positive breast cancer cell lines, such as CAMA-1, but not in MCF-7 cells. Here we show that TRAIL and the Smac mimetic LCL161 induce noncanonical NF-κB and IFN signaling in ER-positive MC

Digest : The role of postzygotic isolation in Mimulus speciation

Recently diverged species often show incomplete reproductive isolation and subsequently experience hybridization and introgression. The plant genus Mimulus includes many such examples of closely related taxa that prove useful for studying incipient speciation. However, Sandstedt et al. show that in contrast to other Mimulus species, species of the M. tilingii complex are characterized by strong po

Checklist, new records, and taxonomic annotations of freshwater thecate dinoflagellate (Dinophyceae) in Colombia

A study on the freshwater dinoflagellate (Dinophyceae) of Colombia was carried out based on samples from four swamps, nine reservoirs, a small insular lake, and additional specimens deposited in the phycological collection of Universidad de Antioquia, Colombia, and the collection of Universidad de La Plata, Argentina. For most species, detailed morphological descriptions and illustrations are prov

A highly conserved ontogenetic limb allometry and its evolutionary significance in the adaptive radiation of Anolis lizards

Diversifications often proceed along highly conserved, evolutionary trajectories. These patterns of covariation arise in ontogeny, which raises the possibility that adaptive morphologies are biased towards trait covariations that resemble growth trajectories. Here, we test this prediction in the diverse clade of Anolis lizards by investigating the covariation of embryonic growth of 13 fore- and hi

Two concerns about the interpretation of the estimates of historical national accounts before 1850

As contribution to the debate about the interpretation of the process of economic growth before the Industrial Revolution, we discuss two concerns about the currently available estimates of historical national accounts and the way in which these estimates should be interpreted. Firstly, we argue that estimates of the long-Term trends of economic growth should make use of all information contained

Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with Β-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing

Mycobacterium tuberculosis remains one of the world's contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and its opportunistic coinfections. The severity of the disease coupled with drug resistance on the currently used drugs warrants for the search for alternative remedies from synthetic

De dövas republik

A translation into Swedish of the poetry collection Deaf Republic (2019) by American poet Ilya Kaminsky

Comprehensive proteomic analysis reveals distinct functional modules associated with skull base and supratentorial meningiomas and perturbations in collagen pathway components

Meningiomas are brain tumors that originate from the meninges and has been primarily classified into three grades by the current WHO guidelines. Although widely prevalent and can be managed by surgery there are instances when the tumors are located in difficult regions. This results in considerable challenges for complete surgical resection and further clinical management. While the genetic signat

Values, science, and competing paradigms in sustainability research: furthering the conversation

Sustainability science is fundamentally a problem-driven and solutions-oriented science which necessitates engagement with questions of interdisciplinarity and normativity. Nagatsu et al. (2020) recently investigated the significance of these peculiar characteristics and produce a useful and timely overview of the problems facing sustainability science, as a science. Perhaps the most crucial and c