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Ultrastructural immunolocalization of cartilage oligomeric matrix protein (COMP) in the articular cartilage on the equine third carpal bone in trained and untrained horses

The present study was designed to delineate the presence of COMP at the ultrastructural level comparing concentrations between two areas of articular cartilage from the equine third carpal bone, subjected to different loading, from trained and untrained horses. We also analyzed the fibril thickness of collagen type II in the same compartments and zones. Samples were collected from high load-bearin

Recruitment advantage of large seeds is greater in shaded habitats

Large seeds are assumed to have higher probability of successful recruitment than small seeds. This is because larger seeds give rise to larger seedlings and larger seedlings better withstand environmental hazards like deep shade and drought. Biotic and abiotic limitations to seedling growth and survival, and conversely availability of safe sites for recruitment, vary along environmental gradients

Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the beta(3)-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes

In adipocytes, PDE3B (phosphodiesterase 3B) is an important regulatory effector in signalling pathways controlled by insulin and cAMP-increasing hormones. Stimulation of 3T3-L1 adipocytes with insulin or the beta(3)-adrenergic receptor agonist CL316243 (termed CL) indicated that insulin preferentially phosphorylated/activated PDE3B associated with internal membranes (endoplasmic reticulum/Golgi),

Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme

Ochratoxin, with ochratoxin A as the dominant form, is one of the five major mycotoxins most harmful to humans and animals. It is produced by Aspergillus and Penicillium species and occurs in a wide range of agricultural products. Detoxification of contaminated food is a challenging health issue. In the present paper we report the identification, characterization and crystal structure (at 2.2 angs

MOA-2010-BLG-523:" Failed Planet"= RS CVn Star

The Galactic bulge source MOA-2010-BLG-523S exhibited short-term deviations from a standard microlensing light curve near the peak of an A(max) similar to 265 high-magnification microlensing event. The deviations originally seemed consistent with expectations for a planetary companion to the principal lens. We combine long-term photometric monitoring with a previously published high-resolution spe

Jet production in ep collisions at high Q(2) and determination of alpha(s)

The production of jets is studied in deep-inelastic e(+/-) p scattering at large negative four momentum transfer squared 150 < Q(2) < 15000 GeV2 using HERA data taken in 1999-2007, corresponding to an integrated luminosity of 395 pb(-1). Inclusive jet, 2-jet and 3-jet cross sections, normalised to the neutral current deep-inelastic scattering cross sections, are measured as functions of Q(2), jet

Aortic Valve Replacement: The Influence of Prosthesis-Patient Mismatch for Left Ventricular Remodeling, Cardiac Function and Survival

The best valve substitute for aortic valve replacement (AVR) in terms of hemodynamic performance, durability, incidence of complications, and survival remains the subject of much debate. It has been suggested that valve performance is influenced by the potentially modifiable variable prosthesis-patient mismatch (PPM). PPM has been reported to be detrimental for survival and symptom resolution main

Use of an Automatic Methane Potential Test System for evaluating the biomethane potential of sugarcane bagasse after different treatments.

A multi-channel analyzer was used to evaluate biogas potential of sugarcane bagasse (SCB). The Automatic Methane Potential Test System contained fifteen parallel reactors and the same number of gas flow meters attached to the acquisition system. The set of reactors - gas flow meters gave reproducible results during anaerobic digestion of chemically defined carbon source and the units were used to

Links between Successful Innovation Diffusion and Stakeholder Engagement

Stakeholders can positively assist or hinder attempts at innovation. Much depends on the nature of their engagement. The stakeholder engagement process can be complex and unpredictable, more so if no strategic plan is put in place or if no systematic thinking is invested in the innovation. Stakeholder engagement in the innovation process in general and innovation diffusion in particular is examine

The upgraded photon tagging facility at the MAX IV Laboratory

A description is given of the upgraded photon tagging facility at the MAX IV Laboratory. Two magnetic spectrometers are used to momentum analyze post-bremsstrahlung electrons. The tagged photon range extends from 10 to 180 MeV with an energy resolution of about 300 keV. The system has been operated at rates up to 4 x 10(6) photons s(-1) MeV (-1). Different diagnostic tools are described as well as

Systematic investigation of residual strains associated with WC-Co coatings thermal sprayed onto metal substrates

Using penetrating high-energy synchrotron X-ray radiation and thermal neutrons, the residual strains and stresses associated with the high-velocity oxygen-fuel (HVOF) thermal spray coating of WC-Co on two different substrate materials with significantly different coefficients of thermal expansion (CTE) to that of the coating material, have been investigated in a systematic approach. This approach

Racemic tricarbonyl(eta 6-7-methoxyflavan)chromium(0)

In the title compound [systematic name: tricarbonyl(eta 6-7-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran)chromium(0)], [Cr(C16H16O2)(CO)(3)], the Cr(CO)(3) unit is coordinated by the phenylene ring of the flavan ligand, exhibiting a three-legged piano-stool conformation, with a point to plane distance of 1.750 (1) A. The phenyl ring is twisted away from the fused ring system by 36.49 (5)degrees (r