Sökresultat

Filtyp

Din sökning på "*" gav 533241 sökträffar

What is bet-hedging, really?

Bet-hedging is defined as a strategy that reduces the temporal variance in fitness at the expense of a lowered arithmetic mean fitness. After a few technical points, we will here argue that this definition of bet-hedging is badly suited for models with density- and/or frequency-dependent fitness. A strict interpretation cannot be employed; possibly, a modified definition is necessary.

Sub-Optimization of a claw-pole structure according to material properties of soft magnetic materials

The focus of this paper is on the development of a single phase PM machine with wave-windings where the design variables are the winding layout and design of a soft magnetic powder core for a stator. A number of BH curves are synthesised in order to characterise some of the existing powder cores and to study the influence of magnetic permeability on starting torque and mean driving torque. The goa

Probing the role of stochasticity in a model of the embryonic stem cell - heterogeneous gene expression and reprogramming efficiency

Background: Embryonic stem cells (ESC) have the capacity to self-renew and remain pluripotent, while continuously providing a source of a variety of differentiated cell types. Understanding what governs these properties at the molecular level is crucial for stem cell biology and its application to regenerative medicine. Of particular relevance is to elucidate those molecular interactions which gov

Budesonide added to formoterol contributes to improved exercise tolerance in patients with COPD

Background: Breathlessness and exercise intolerance frequently impact the daily life of patients with COPD. Methods: This double-blind, multicentre, three-period crossover study randomised 111 patients with COPD (mean age 64 years, mean FEV1 38% of predicted normal) to budesonide/formoterol 320/9 mu g, formoterol 9 mu g or placebo, twice daily for 1 week, following a 1-week run-in period with 1-we

Unveiling and controlling the electronic structure of oxidized semiconductor surfaces: Crystalline oxidized InSb(100)(1 x 2)-O

The exothermic nature of oxidation causes nearly all semiconductor applications in various fields like electronics, medicine, photonics, and sensor technology to acquire an oxidized semiconductor surface part during the application manufacturing. The significance of understanding and controlling the atomic scale properties of oxidized semiconductor surfaces is expected to increase even further wit

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

Nonsense-mediated mRNA decay (NMD) is a post-transcriptional surveillance process that eliminates mRNAs containing premature termination codons (PTCs). NMD has been hypothesized to impact on several aspects of cellular function; however, its importance in the context of a mammalian organism has not been addressed in detail. Here we use mouse genetics to demonstrate that hematopoietic-specific dele

Trade Facilitation and the EU-ACP Economic Partnership Agreements

This paper assesses the potential effects from trade facilitation in terms of increased trade flows both on average and specifically for the six regional groups of ACP countries negotiating Economic Partnership Agreements (EPAs) with the EU. Data from the World Bank’s Doing Business Database on the time required to export or import are used as indicators of cross-border transaction costs, and a gr

When the dust has settled: A final note on replication

Honing and Samuelsson have in a two papers (2014, 2015) criticized the Delmar and Shane (2003) paper on several grounds: The data are difficult to replicate; conflicting results with another paper using the same data and similar independent variable; the inability to fully rule out reversed causality because of tied events; and what is the choice of relevant dependent variable. I also commented on

Medkänslans makt och gränser. Nya linjer i känslornas historia

Den här artikeln belyser hur långa linjer kan bedrivas också kring känslor som omsorg och medkänsla. Därigenom önskar vi nyansera en traditionell berättelse om västerlandets historia, som i hög grad förklarat historien som en förnuftslig och handgriplig triumf över tidigare dominerande känslor som ångest och rädsla. En sådan förklaringsmodell baseras på teorier om känslor som inte längre har stöd

Classification, incidence and survival analyses of children with CNS tumours diagnosed in Sweden 1984-2005

Aim: Primary tumours in the central nervous system (CNS) are the second most common malignancy in childhood after leukaemia. Sweden has a high incidence and a high-survival rate in international comparative studies. This has raised the question about the type of tumours included in the Swedish Cancer registry. We therefore compared international data to the Swedish Childhood Cancer registry. Metho

Kejsarens nya kläder - implementering av evidensbaserad praktik i socialt arbete

Stat och kommun träffade 2010 en grundöverenskommelse om att införa en evidensbaserad praktik inom socialtjänsten. Sedan dess har överenskommelsen preciserats, en process som analyseras i denna artikel. Som vi kommer att visa återstår betydande oklarheter som det sociala arbetets aktörer behöver klargöra via förhandlingar. Detta är ett numera vanligt sätt att söka implementera politik och vi disku