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Healthcare use in 700 000 children and adolescents for six months after covid-19 : before and after register based cohort study

Objectives To explore whether and for how long use of healthcare services is increased among children and adolescents after covid-19. Design Before and after register based study. Setting General population of Norway. Participants Norwegians aged 1-19 years (n=706 885) who were tested for SARS-CoV-2 from 1 August 2020 to 1 February 2021 (n=10 279 positive, n=275 859 negative) or not tested (n=420

Benjamin Esterman (1906–1994) and the binocular visual field scoring grid that became a world standard for assessing driver eligibility

The visual field grid developed by the ophthalmologist Benjamin Esterman (1906-1994) is today an accepted standard for assessing driver eligibility in many parts of the world. However, little is published about the scientific process that led to the test or about the person who developed it. The aim of this article is to portray the ophthalmologist Benjamin Esterman, and to discuss the visual fiel

The best approach for functional tricuspid regurgitation : A network meta-analysis

Objective: For many years, functional tricuspid regurgitation (FTR) was considered negligible after treatment of left-sided heart valve surgery. The aim of the present network meta-analysis is to summarize the results of four approaches to establish the possible gold standard. Methods: A systematic search was performed to identify all publications reporting the outcomes of four approaches for FTR,

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype1-3. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls, plus 18,908 BRCA1 mutation carriers (9,414 with breast cancer) of European ancestry, using both standard and novel methodologies that account for underlying tumor het

Towards Knowledge-Based Geospatial Data Integration and Visualization : A Case of Visualizing Urban Bicycling Suitability

Geospatial information plays an indispensable role in various interdisciplinary and spatially informed analyses. However, the use of geospatial information often entails many semantic intricacies relating to, among other issues, data integration and visualization. For the integration of data from different domains, merely using ontologies is inadequate for handling subtle and complex semantic rela

Multi-criteria spatial-based modelling for optimal alignment of roadway by-passes in the Tlokweng planning area, Botswana

In this study, Spatial Multi-Criteria Evaluation and the least cost path analysis were applied to find the optimal by-pass road alignment in the Tlokweng Planning Area in Botswana. One-At-a-Time sensitivity analysis and the statistical test for zero proportion were used to investigate the robustness of the entire model. Four alternative by-pass roads were produced stressing economic, environmental

Tidal Volume Lowering by Instrumental Dead Space Reduction in Brain-Injured ARDS Patients : Effects on Respiratory Mechanics, Gas Exchange, and Cerebral Hemodynamics

Background: Limiting tidal volume (VT), plateau pressure, and driving pressure is essential during the acute respiratory distress syndrome (ARDS), but may be challenging when brain injury coexists due to the risk of hypercapnia. Because lowering dead space enhances CO2 clearance, we conducted a study to determine whether and to what extent replacing heat and moisture exchangers (HME) with heated h

Alkali Salts as Interface Modifiers in n-i-p Hybrid Perovskite Solar Cells

After demonstration of a 23% power conversion efficiency, a high operational stability is the next most important scientific and technological challenge in perovskite solar cells (PSCs). A potential failure mechanism is tied to a bias-induced ion migration, which causes current–voltage hysteresis and a decay in the device performance over time. Herein, alkali salts are shown to mitigate hysteresis

Physiotherapists’ experiences of the meaning of movement quality in autism: a descriptive phenomenological study

Introduction: Movement quality, represented in unrestricted movements, flow and pleasure, is often lacking in people with autism. One aspect is the non-verbal expression of the present emotional and psychological state of an individual. Purpose: To describe the meaning of movement quality in autism, as experienced by specialized physiotherapists. Method: Ten physiotherapists were interviewed. The

Building polymer-like clusters from colloidal particles with isotropic interactions, in aqueous solution

Hypothesis: Colloidal particles that interact via a long-ranged repulsive barrier in combination with a very short-ranged attractive minimum can “polymerize” to form highly anisotropic structures. Motivated by previous experimental achievements in non-aqueous solvents, and recent theoretical predictions, we hypothesize that it is possible to construct clusters that resemble linear or branched poly

Trends in the prevalence, incidence and survival of non-Hodgkin lymphoma subtypes during the 21st century – a Swedish lymphoma register study

Non-Hodgkin lymphoma (NHL) prognosis has improved in recent years, yet the number of patients living with the diagnosis, i.e. the prevalence, has seldom been reported. The prevalence provides a measure of the burden of disease, useful for healthcare planning and to optimise resource allocation. We provide a systematic presentation of temporal trends in absolute numbers of prevalent patients by NHL

Modelling human rostro-caudal neural patterning with a microfluidic morphogenic gradient

The study of biological mechanisms involved in human fetal brain development requires suitable models. To date, most findings have been acquired from animal models that fail to account for human-specific developmental traits. To counteract this limitation, a novel in vitro model is proposed where human pluripotent stem cells are differentiated into a coherent fetal brain tissue in a gradient formi

Half-panel jackknife estimation for dynamic panel models

This paper extends the half-panel jackknife (HPJ) estimator to GMM models with fixed effects. The Monte Carlo results show that the HPJ significantly reduces finite-sample bias for both the difference and system GMM estimators of the dynamic panel model.

Evolution of collective and noncollective structures in Xe 123

An experiment involving a heavy-ion-induced fusion-evaporation reaction was carried out where high-spin states of Xe123 were populated in the Se80(Ca48,5n)Xe123 reaction at 207 MeV beam energy. Gamma-ray coincidence events were recorded with the Gammasphere Ge detector array. The previously known level scheme was confirmed and enhanced with the addition of five new band structures and several inte

Nanowire Solar Cells : A New Radiation Hard PV Technology for Space Applications

Radiation hard thin-film solar cell technologies are necessary in order to achieve a step forward in the specific power of solar arrays for space applications. In this article, we analyze the degradation of nanowire (NW) solar cells under high energy particles. GaAs NW solar cells have been irradiated with protons of 100 and 350 keV at different fluences. The radiation hardness of the NW solar cel

Electric bike navigation behaviour in pedestrian crowds

This study investigates the influence of pedestrian crowdedness on e-bike navigation behaviour in a controlled field experiment. The dataset includes a total of 1520 trajectories, including 18 pedestrians and one e-bike at a time. Based on the e-bike navigation through the pedestrians, the so-called “hindrance” concept was used to classify the data into two phases: passing (same-direction encounte