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Combinatorial molecule screening identifies a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells

Combination treatment has proven effective for patients with acute promyelocytic leukemia, exemplifying the importance of therapy targeting multiple components of oncogenic regulation for a successful outcome. However, recent studies have shown that the mutational complexity of acute myeloid leukemia (AML) precludes the translation of molecular targeting into clinical success. Here as a complement

Aspects of pediatric hemodynamics. A study of young children undergoing corrective heart surgery.

AbstractBackground: Assessing critically ill patients is demanding because their clinical signs are not always easy to interpret. This is particularly true for pediatric patients, due to their small size and robust circulatory compensatorymechanism. Physicians working in pediatric intensive care settings seldom use invasive monitoring, due to possible complications and the risks involved. Instead,

The Privilege to Select : Global Research System, European Academic Library Collections, and Decolonisation

A large part of the literature published in the ‘Global South’ is barely covered by bibliographic databases. Institutional policies increasingly require researchers globally to publish in ‘international’ journals, draining local infrastructures. The standard-setting power of ‘Global South’ scholars is minimised further. My main aim is to render visible the ways in which European academic libraries

A Food Nation Without Culinary Heritage? Gastronationalism in Sweden

Promoting the culinary profile of a nation is a commonly used tool when marketing the food, drink, and culinary tourism sectors of a country. Different versions of gastronationalism (i.e., images of the culinary excellence of a nation) appear in this context. This article explores Swedish gastronationalism. The aim is to nuance and widen the discussion of gastronationalism by offering a historic c

Insect pollination of oilseed rape

Ecological intensification of agriculture is suggested as a way to reach higher crop yields without increasing inputs that may degrade the environment. Increased insect pollination in crops, such as oilseed rape, Brassica napus, has been suggested to increase yields, but is rarely integrated in crop management. To determine the value of enhanced crop pollination as a means of ecological intensific

Effects of agricultural intensity and landscape complexity on plant species richness

Jordbrukets intensitet har under de senaste decennierna ökat genom effektiviserad teknikanvändning och ökade insatser av pesticider och växtnäring. Detta har inte bara lett till ökade skördar utan även till negativa konsekvenser för den biologiska mångfalden i jordbrukslandskapet.I denna studie inventerades förekomsten av kärlväxter i 160 höstvetefält (Triticum aestivum L.) på 32 gårdar i Uppsala-

International Trade and Labor Market Integration of Immigrants

We examine if international trade improves labor market integration of immigrants in Sweden. Immigrants participate substantially less than natives in the labor market. However, trading with a foreign country is expected to increase the demand for immigrants from that country. By hiring immigrants, a firm may access foreign knowledge and networks needed to overcome information frictions in trade.