Sökresultat

Filtyp

Din sökning på "*" gav 535450 sökträffar

Is there an underestimation of intima-media thickness based on M-mode ultrasound technique in the abdominal aorta?

Measuring intima-media thickness (IMT) in the common carotid artery (CCA) is a valuable resource for the evaluation of subclinical atherosclerosis. The main objective of this study was to explore whether a B-mode ultrasound technique, Philips ATL, and an M-mode ultrasound technique, Wall Track System (WTS), show interchangeable results when measured in CCA and the abdominal aorta (AA). A total of

MALDI-target integrated platform for affinity-captured protein digestion.

To address immunocapture of proteins in large cohorts of clinical samples high throughput sample processing is required. Here a method using the proteomic sample platform, ISET (integrated selective enrichment target) that integrates highly specific immunoaffinity capture of protein biomarker, digestion and sample cleanup with a direct interface to mass spectrometry is presented. The robustness of

The role of small airway disease in asthma.

This review provides an update on the importance of the peripheral 'small' airways in asthma. As the small airways account for less than 10% of total airway resistance, thus having little impact on standard lung function measures such as forced expiratory volume and peak flow, they have been referred to as the 'silent zone'.

Prophylactic treatment with proton pump inhibitors in children operated on for oesophageal atresia.

Introduction Oesophageal stricture is a frequent complication following repair of oesophageal atresia (EA). The aim of this study was to conduct a pre- and postintervention study and analyze the incidence of stricture formation and need for balloon dilatation after introducing prophylactic proton pump inhibitor (PPI) treatment.Children and Design All children operated for EA during 2001 to 2009 (n

Chemical composition of Late Svecofennian granite in the Bothnian Basin, central Sweden

Late Svecofennian granite is frequent in the Bothnian Basin, especially in zones of rapidly changing metamorphic grade but also in areas, where the metamorphic grade is elevated. The granite is essentially undeformed, but weakly foliated or lineated rocks are common; more rarely are rocks strongly foliated. X-ray fluorescence was used for major-element and ICP-MS for trace-element analyses. The ch

Observation of Periodic Orbits on Curved Two-Dimensional Geometries

We measure elastomechanical spectra for a family of thin shells. We show that these spectra can be described by a "semiclassical'' trace formula comprising periodic orbits on geodesics, with the periods of these orbits consistent with those extracted from experiment. The influence of periodic orbits on spectra in the case of two-dimensional curved geometries is thereby demonstrated, where the para

Inviting the messy: Drawing methods and 'children's voices'

This article engages with the current debate in childhood research on children’s voices and representation in the research process. In this discussion, the frequent use of drawing techniques in childhood research is often highlighted as especially problematic. While agreeing that there is a need to critically examine the concept of ‘children’s voices’ and the production of ‘voices’ in research, th

Stability and performance of cation vacant Fe3-x-yVx□yO4 spinel phase catalysts in methanol oxidation

A series of spinel type Fe-V-O phases were prepared with V/Fe atomic ratios ranging from 0 to 1 and were used for methanol oxidation to formaldehyde. X-ray powder diffraction shows that the basic spinel-type structure is retained after use of the samples in methanol oxidation. Compared with the freshly prepared samples, in and ex situ analyses of the samples with XANES show that both V and Fe are

Conceptual Mean-Line Design of Single and Twin-Shaft Oxy-Fuel Gas Turbine in a Semiclosed Oxy-Fuel Combustion Combined Cycle

The aim of this study was to compare single-and twin-shaft oxy-fuel gas turbines in a semiclosed oxy-fuel combustion combined cycle (SCOC-CC). This paper discussed the turbomachinery preliminary mean-line design of oxy-fuel compressor and turbine. The conceptual turbine design was performed using the axial through-flow code LUAX-T, developed at Lund University. A tool for conceptual design of axia

Study of the Early Flame Development in a Spark-Ignited Lean Burn Four-Stroke Large Bore Gas Engine by Fuel Tracer PLIF

In this work the pre- to main chamber ignition process is studied in a Wärtsilä 34SG spark-ignited lean burn four-stroke large bore optical engine (bore 340 mm) operating on natural gas. Unburnt and burnt gas regions in planar cross-sections of the combustion chamber are identified by means of planar laser induced fluorescence (PLIF) from acetone seeded to the fuel. The emerging jets from the pre-

Characterization of ammonia two-photon laser-induced fluorescence for gas-phase diagnostics

Two-photon laser-induced fluorescence (LIF) of ammonia (NH3) with excitation of the C'-X transition at 304.8 nm and fluorescence detection in the 565 nm C'-A band has been investigated, targeting combustion diagnostics. The impact of laser irradiance, temperature, and pressure has been studied, and simulation of NH3-spectra, fitted to experimental data, facilitated interpretation of the results. T

Effect of partial premixing on stabilization and local extinction of turbulent methane/air flames

Abstract in UndeterminedThe stabilization characteristics and local extinction structures of partially premixed methane/air flames were studied using simultaneous OH-PLIF/PIV techniques, and large eddy simulations employing a two-scalar flamelet model. Partial premixing was made in a mixing chamber comprised of two concentric tubes, where the degree of partial premixing of fuel and air was control

Alveolar T-helper type-2 immunity in atopic asthma is associated with poor clinical control

Real-world evaluation studies have shown that many patients with asthma remain symptomatic despite treatment with inhaled corticosteroids (ICSs). As conventional ICSs have poor access to the peripheral airways, the aim of the present paper was to study the relationship between peripheral airway inflammation and clinical control in allergic asthma. Consequently, bronchial and transbronchial biopsie

Search for high-mass diphoton resonances in pp collisions at pffisffi root s=8 TeV with the ATLAS detector

This article describes a search for high-mass resonances decaying to a pair of photons using a sample of 20.3 fb(-1) of pp collisions at root s = 8 TeV recorded with the ATLAS detector at the Large Hadron Collider. The data are found to be in agreement with the Standard Model prediction, and limits are reported in the framework of the Randall-Sundrum model. This theory leads to the prediction of g

Climate change, values, and the cultural cognition thesis

Recently the importance of addressing values in discussions of risk perception and adaptation to climate change has become manifest. Values-based approaches to climate change adaptation and the cultural cognition thesis both illustrate this trend. We argue that in the wake of this development it is necessary to take the dynamic relationship between values and beliefs seriously, to acknowledge the

EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein

Many bacteria have evolved ways to interact with glycosylation functions of the immune system of their hosts. Streptococcus pyogenes [GAS (group A Streptococcus)] secretes the enzyme EndoS that cleaves glycans on human IgG and impairs the effector functions of the antibody. The ndoS gene, encoding EndoS, has, until now, been thought to be conserved throughout the serotypes. However, in the present

A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes

Previous studies have shown that stimulation of whole blood or peripheral blood mononuclear cells with bacterial virulence factors results in the sequestration of pro-coagulant microvesicles (MVs). These particles explore their clotting activity via the extrinsic and intrinsic pathway of coagulation; however, their pathophysiological role in infectious diseases remains enigmatic. Here we describe

Prevalence and characteristics of the metabolic syndrome in 2479 hypopituitary patients with adult-onset GH deficiency before GH replacement: a KIMS analysis

Objective: An increased risk of cardiovascular morbidity and mortality in adult GH deficiency (GHD) may be related to hypopituitarism but also to the presence of the metabolic syndrome (MetS). Our objective was to investigate the characteristics and prevalence of MetS as well as its comorbidities in adult GHD. Design: In KIMS (Pfizer International Metabolic Database) 2479 patients with severe adul

Human variome project country nodes: Documenting genetic information within a country

The Human Variome Project (http://www.humanvariomeproject.org) is an international effort aiming to systematically collect and share information on all human genetic variation. The two main pillars of this effort are gene/disease-specific databases and a network of Human Variome Project Country Nodes. The latter are nationwide efforts to document the genomic variation reported within a specific po