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During the last decade, the varying use and the lack of consistent indications for blood transfusions have been questioned. Comparisons of liberal and restrictive transfusion policies, most often support a restrictive policy. This has led to an evidence-based approach to optimizing the care of patients who might need transfusion, Patient Blood Management (PBM). There is evidence that both anemia a

BACKGROUND: Community acquired pneumonia (CAP) remains a significant cause of morbidity and in-hospital mortality, and readmission rates are rising for older persons (> 65 years). Optimized treatment and nursing care will benefit patients and the health economy. Hence, there is a need to describe gaps between current clinical practice and recommendations in evidence-based guidelines for diagnostic

Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable tumour control and result in the long-term survival of patients with advanced cancers1. Current predictive biomarkers for therapy response include high levels of intratumour immunological activity, a high tumour mutational burden and specific characteristics of the gut microbiota2,3. Although the role of T c

BACKGROUND: Girls and women with Rett Syndrome (RTT) have low levels of daily physical activity and high levels of sedentary time. Reducing sedentary time and enhancing "uptime" activities, such as standing and walking, could be an important focus for interventions to address long-term health and quality of life in RTT. OBJECTIVE: The aim of the study was to evaluate the feasibility and health-rel

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In massive multiple-input multiple-output (MIMO) systems, the large size of channel state information (CSI) matrix significantly increases the computational complexity of uplink detection and size of required memory to store the channel data. To address these challenges, we propose to perform detection in the angular domain, where the channel information can be presented in a more condensed way. T

This article analyses sibling farms in Sweden during the 20th century. The term sibling farm refers to a farm that two or more adult siblings have taken over from their parents. Although varied research themes have focused on a rangeof topics, this form of extended family constellation is traditionally associated with the past, whereas the smaller, nuclear family is characterized as modern. When r

Nils Wohlin and the question of inheritance patternsIt has long been assumed that inheritance patterns varied strongly betweendifferent regions. In the early 20th century statistician Nils Wohlin made afamous account of Swedish inheritance patterns, claiming significant differences between Swedish provinces, especially between eastern and western Sweden. Newer studies of inheritance patterns have