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Defining Human Enhancement : Towards a Foundational Conceptual Tool for Enhancement Law

Emerging technologies open the prospect of extraordinary interventions on the human body. These may go beyond what is strictly necessary to sustain health and well-being. While responding to social and ethical challenges of such advances, the Law simultaneously faces the challenge of reflecting on the legitimacy to legislate and on whether the existing legal framework is appropriate to address the

Cutting Edges and Weaving Threads in the Gene Editing (Я)evolution : Reconciling scientific progress with Legal, Ethical, & Social concerns

Gene editing technologies, such as CRISPR/Cas9, hold great promises for the advancement of science and technology. These foundational technologies enable to modify the genetic structure of living organisms with unprecedented precision. Potential applications include both plant, animal and human genetic interventions. In plant biology, gene editing introduces more precise, target- and time-efficien

Temperature-controlled airflow ventilation in operating rooms compared with laminar airflow and turbulent mixed airflow

Aim: To evaluate three types of ventilation systems for operating rooms with respect to air cleanliness [in colony-forming units (cfu/m3)], energy consumption and comfort of working environment (noise and draught) as reported by surgical team members. Methods: Two commonly used ventilation systems, vertical laminar airflow (LAF) and turbulent mixed airflow (TMA), were compared with a newly develop

Security

This chapter offers a review of the literature in the field of critical security studies in order to discuss the various social constructions of climate change as a security issue and their policy implications. Will climate security discourse facilitate climate mitigation policy? First, the Copenhagen School asks whether extraordinary measures to protect the climate (including emission reductions)

Home setting after stroke, facilitators and barriers : A systematic literature review

This paper seeks to improve the understanding of the interaction between patients with stroke and the physical environment in their home settings. Stroke care is increasingly performed in the patient's home. Therefore, a systematic review was conducted to identify the existing knowledge about facilitators and barriers in the physical environment of home settings for the stroke rehabilitation proce

Pulmonell hypertension vanligt vid vänstersidig hjärtsjukdom

Pulmonell hypertension är en vanlig komplikation till vänstersidig hjärtsjukdom och medför såväl försämrad livskvalitet som försämrad prognos.Den pulmonella hypertensionen beror initialt på passiv stockning av blod i lungkretsloppet men kan kompliceras av såväl pulmonell vasokonstriktion som vaskulär remodulering.2015 års europeiska riktlinjer innefattar en ny definition av pulmonell hypertension Pulmonary hypertension (PH) is a serious complication to left heart disease (LHD), affecting a majority of the patients during the course of the disease. Initially, PHLHD is caused by passive congestion of the pulmonary vessels due to increased left atrial pressures, a condition that is currently denoted as isolated post-capillary PH (Icp-PH). In the majority of patients the increased atrial press

Outcomes of liver-first strategy and classical strategy for synchronous colorectal liver metastases in Sweden

Background: Patients with synchronous colorectal liver metastases (sCRLM) are increasingly operated with liver resection before resection of the primary cancer. The aim of this study was to compare outcomes in patients following the liver-first strategy and the classical strategy (resection of the bowel first) using prospectively registered data from two nationwide registries. Methods: Clinical, p

Tumor characteristics and prognosis in women with pregnancy-associated breast cancer

There is evidence of poor prognosis in women with pregnancy-associated breast cancer (PABC) diagnosed during pregnancy or within 2 years of delivery. Using a large, population-based cohort, we examined clinicopathologic features and survival in women with PABC. A cohort of women diagnosed with invasive breast cancer between 1992 and 2009 at ages 15-44 years was identified in the Swedish Cancer Reg

Parental health and psychosomatic symptoms in preschool children : A cross-sectional study in Scania, Sweden

Aim: The aim of the study was to assess the association between parental self-rated health and recurrent abdominal pain (RAP) in preschool children. Methods: A questionnaire, including questions about sociodemographic and psychosocial factors, lifestyle, parental and child health, was sent to parents of all 4-year-old children in Scania, Sweden. The response rate was 43.6%. The outcome was RAP and

A comparative study found that a seven-year school-based exercise programme increased physical activity levels in both sexes

Aim: This study assessed whether a Swedish school-based exercise intervention programme could increase total physical activity. Methods: We followed up 228 children who started school in 1998-2000 seven years later, when they had reached a mean age of 14.8. The 152 children (59% boys) at the intervention school did 200 minutes of physical education per week during that period, and the 76 children

Outcome and Complications Using Negative Pressure Wound Therapy in the Groin for Perivascular Surgical Site Infections after Vascular Surgery

Background: The aim of this study was to investigate graft preservation, major bleeding, and reinfection rate using negative pressure wound therapy (NPWT) for perivascular surgical site infections (SSIs) in the groin after vascular surgery and factors associated with failure of treatment. Methods: Retrospective data were collected during 2004-2015. Failure of wound treatment was defined as a wound

Correlation of seminar attendance and written examinations in medical education

Objectives: The parts of constructive alignment, i.e. learning objectives, activities and assessment are crucial for good learning outcomes. However, they must constantly be evaluated so as to verify the alignment. Our aim was to investigate if attendance to our casebased seminars in family medicine contributed to exam performance and whether gender had any impact for undergraduate students at the