Research has identified the central role played by shame within a wide spectrum of public health issues including several common and serious threats to psychological and physical public health including depressions, dependency of substances, eating disorders, suicide, violence and sexual abuse. Shame has been described as “the master emotion of everyday life” but it is an emotional condition which

Diskussioner om entreprenörskap och idén om entreprenören har blivit alltmer framträdande – men för detta inte mer tydlig. Denna studie undersöker hur diskussioner om entreprenören formas diskursivt. Syftet med studien är att förstå hur representationer och mönster i talet om entreprenören konstituerar en diskurs om entreprenören som ideal. Analysmaterialet består av videor om entreprenören i sociDiscussions about entrepreneurship and the idea of the entrepreneur have become increasingly prominent – all the while not any clearer. This study investigates how discussions about the entrepreneur are shaped discursively. The purpose of the study is to make sense of how representations as well as patterns in the speech about the entrepreneur constitutes a discourse about the entrepreneur as an i

Due to the widespread juvenile delinquency in Sweden, attention has been brought to the need for more intrusive penalties for young offenders. Therefore, the penalty of youth probation (Sw. ungdomsövervakning) was legislated in 2021, which aims to counteract recidivism and contribute to a favorable development of young offenders. Previous literature reveals that there is no agreement in the effect

L-DOPA-induced dyskinesia (LID) in Parkinson’s disease has been linked to oscillatory neuronal activities in the cortico-basal ganglia network. We set out to examine the pattern of cortico-basal ganglia oscillations induced by selective agonists of D1 and D2 receptors in a rat model of LID. Local field potentials were recorded in freely moving rats using large-scale electrodes targeting three moto

I den här rapporten analyseras ett urval av de totalt 100 projekt som ingått i Arvsfondens Nyanländasatsning vilken hade till syfte att stärka nyanlända barns och ungas etablering och delaktighet i samhället. Rapporten bygger på tre delstudier. En dokumentstudie bestående av ansökningshandlingar, årsrapporter och i förekommande fall slutrapporter från projekten, en enkät omfattande 89 av sats

We optimize traffic signal timing sequences for a section of a traffic net-work in order to reduce congestion based on anticipated demand. The system relieson the accuracy of the predicted traffic demand in time and space which is carriedout by a neural network. Specifically, we design, train, and evaluate three differentneural network models and assert their capability to describe demand from tra

Peace agreements, especially those signalling the end of internal armed conflicts, can be understood as blueprints of the envisioned peacebuilding. This chapter provides a discursive analysis of 130 peace agreements from interstate and intrastate conflicts in Africa between 1990 and 2019 which have provisions on women, girls or gender. The aim is to explore how women, their roles and functions are

A 33-kD glycoprotein, known as the 'prostate-specific antigen', was purified to homogeneity from human seminal plasma. The prostatic protein was identified as a serine protease, and its NH2-terminal sequence strongly suggests that it belongs to the family of glandular kallikreins. The structural protein of human seminal coagulum, the predominant protein in seminal vesicle secretion, was rapidly cl

Purpose: To assess the feasibility of characterizing gene copy number alteration by fluorescence in situ hybridization (FISH) of circulating tumor cells (CTC) isolated using the Cell Search system in patients with progressive castration-resistant metastatic prostate cancer. Experimental Design: We used probe combinations that included the androgen receptor (AR)and MYC genes for FISH analysis of CT

Most pretreatment risk-assessment models to predict biochemical recurrence (BCR) after radical prostatectomy (RP) for prostate cancer rely on total prostate-specific antigen (PSA), clinical stage, and biopsy Gleason grade. We investigated whether free PSA (fPSA) and human glandular kallikrein-2 (hK2) would enhance the predictive accuracy of this standard model. Preoperative serum samples and compl

Dementia have substantial negative impact on the affected individual, their care partners and society. Persons living with Parkinson’s disease (PwP) are also to a large extent living with dementia. The aim of this study is to estimate time to dementia in PD using data from a large quality register with access to baseline clinical and patient reported data merged with Swedish national health regist

Bladder exstrophy is a rare congenital malformation leaving the urinary bladder open in the midline of the abdomen at birth. There is a clear genetic background with chromosome aberrations, but so far, no consistent findings apart from 22q11-duplications detected in about 2%–3% of all patients. Some genes are implicated like the LZTR1, ISL1, CELSR3, and the WNT3 genes, but most are not explained m

The introduction of total prostate-specific antigen (tPSA) testing in serum has revolutionized the detection and management of men with prostate cancer. This review will highlight some of the exciting new developments in the field of prostate cancer screening in general and from our SPORE research program at Memorial-Sloan Kettering Cancer Center. First, it is important to understand that the inhe

Microgravity-induced bone loss is a major concern for space travelers. Ground-based microgravity simulators are crucial to study the effect of microgravity exposure on biological systems and to address the limitations posed by restricted access to real space. In this work, for the first time, we adopt a multidisciplinary approach to characterize the morphological, biochemical, and molecular change

Understanding influence of vegetation on past temperature changes in the Arctic region would help isolate uncertainty and build understanding of its broader climate system, with implications for paleoclimate reconstructions and future climate change. Using an Earth system model EC-Earth, we conduct a series of simulations to investigate the impact of vegetation-climate feedback on the Arctic clima

The Art Museum has long acted as a complex and multifaceted symbol of power, exclusion and liberation. In recent time, the Art Museum’s position has shifted from a place of fine culture, a space that separate the elite from “the others”, to undergo a democratization in an attempt to reach a wider audience and become more accessible. At the same time, there is a conflict regarding the Art Museum wh

Studying migrants from Sweden to the United States, we provide new evidence on return migration during the Age of Mass Migration. Focusing on a sample of migrants and stayers observed in childhood, we document limited effects on income and occupational upgrading, but large effects on wealth. Male returnees held about twice as much wealth as stayers and about 40 percent more than staying brothers.