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This review covers the main principles of the Lund concept for treatment of severe traumatic brain injury. This is followed by a description of results from clinical studies in which this therapy or a modified version of the therapy has been used. Unlike other guidelines, which are based on meta-analytical approaches, important components of the Lund concept are based on physiological mechanisms f
It has long been known that the iridescent cuticle of many scarab beetles reflects circularly polarised light. It now turns out that scarabs can also see this light, potentially using it as a covert visual signal.
Objectives: To investigate the predictive value of cystatin C among patients diagnosed with non-ST-elevation acute coronary syndrome (nSTE-ACS). Design and methods: Admission serum samples from 245 nSTE-ACS patients were measured with a novel cystatin C immunoassay based on a dry-reagent, double monoclonal design. Creatinine concentrations, estimated glomerular filtration rates (eGFR) and one-year
Permanent offspring modification through maternal hormone transfer is thought to be a tool for mothers to influence life-history trajectories of individual offspring. In birds, yolk hormones influence numerous aspects of the offspring's physiology, including antioxidant status, an important physiological measure that is linked to growth, reproductive effort, and survival. While it is evident that
Inflammation is a growing area of research in neurodegeneration. In Huntington's disease (HD), a fatal inherited neurodegenerative disease caused by a CAG-repeat expansion in the gene encoding huntingtin, patients have increased plasma levels of inflammatory cytokines and circulating monocytes that are hyper-responsive to immune stimuli. Several mouse models of HD also show elevated plasma levels
Purpose: To presents results after 18 months of follow-up of a longitudinal study aiming at exploring the correlation between diabetic retinal vascular lesions and functional change. Methods: Patients were consecutively recruited from attendees to the screening program for diabetic retinopathy. Subjects are followed every sixth month for the first 3 years and thereafter annually up to 5 years. Pro
Aqueous solutions of charged spherical macroions with variable dielectric permittivity and their associated counterions are examined within the cell model using a field theory and Monte Carlo simulations. The field theory is based on separation of fields into short- and long-wavelength terms, which are subjected to different statistical-mechanical treatments. The simulations were performed by usin
Polyethylene is the most frequently used polymer material in food packaging today. The polymer is often processed by film extrusion and extrusion coating between 250°C and 325°C. Although polyethylene has high thermal stability some degradation takes place and the degradation products formed will migrate to the packed food, which will give food off-flavour tastes when consumed. With an increase in
Abstract in Norwegian Hva mener vi når vi sier at noe er rettferdig eller likt fordelt? Statsvitere søker svar på slike store spørsmål – om krig og fred, rett og urett, miljø og global ressursfordeling. Men statsvitere interesserer seg også for det mer lokale og hverdagslige. Hvorfor stemte folk som de gjorde i forrige lokalvalg? Hvorfor er det av og til så vanskelig å gjennomføre politiske beslut
The main objective of this paper is to develop a proven model which allows the study of the non-stationary effects in district heating systems, which are associated with time lag, between heat generation and the final consumption of the heat. A finite element model was developed which incorporates one-dimensional fluid elements together with thermal elements sets. This enables a description of the
The deterministic approach for the prediction of noise in electrical machines is generally based on the use of FEM/BEM models. Mechanical and electromagnetic properties included in these models, such as the damping or the BH curve, are difficult to estimate, compromising the accuracy in the noise prediction. Simulations showed that a 10% increase in the saturated part of the BH curve results in an
In this study a dynamic model of a solid oxide fuel cell (SOFC) system has been developed. The work has been conducted in a cooperation between the Department of Energy Sciences, Lund University, and Mode Ion AB using the Modelica language and the Dymola modeling and simulation tool. Modelica is an equation based, object oriented modeling language, which promotes flexibility and reuse of code. The
A modern control system is typically implemented as a multitasking software application executing in a real-time operating system. If the computer load is high, the controller will experience delays and jitter, which in turn degrade the control performance. Arguing for an integrated design approach, the paper describes two computer tools for implementation-aware control analysis: TrueTime and Jitt
The aim of the work presented in this thesis was to improve ethanol formation from xylose in recombinant Saccharomyces cerevisiae strains. This was achieved by decreasing the xylitol by-product formation. Gre3p is the major xylose-reducing enzyme in S. cerevisiae. Ypr1p, Gcy1p and the protein encoded by YJR096w also have the ability to reduce xylose in cell extracts. Furthermore, Gre3p, Ypr1p, Gc
