Factor V:Q506 causing resistance to activated protein C (APC-resistance), is a risk factor for venous thrombosis. Some studies have indicated an association with arterial disease, especially in women. We investigated the prevalence of the FV:Q506 allele prospectively in 295 patients with acute coronary syndrome. Mortality and myocardial infarction rate were evaluated after 30 days and after 2 year

OBJECTIVE: To examine the expression pattern of matrix metalloproteinase-26 (MMP-26) mRNA and estrogen receptor-alpha (ER alpha) in normal, hyperplastic, premalignant and malignant endometrial tissue. DESIGN: Experimental study. SETTING: Department of Obstetrics and Gynecology of the Palacky University Medical School and University Hospital, Olomouc, Czech Republic, Department of Obstetrics and Gy

Introduction: The proportion of elderly patients who are undernourished is high and undernutrition has serious health implications. No consensus exists regarding nutritional screening measurements suitable for elderly patients. There is a need to identify risk factors for undernutrition in elderly patients to enable prevention and treatment. Aim: To identify clinically identifiable risk factors fo

Patients attending the emergency room with acute asthma, participating in a study comparing salbutamol (albuterol in the United States) via a dry powder inhaler (Turbuhaler) with pressurized metered-dose inhaler (pMDI), were included in this 1-week follow-up study with the aim of assessing whether inhaled budesonide via Turbuhaler may be an alternative to prednisolone tablets after an acute asthma

spruce stands, pure Norway spruce, pure birch and mixed plots of birch and Norway spruce were established in 1984/1985 at four locations in southern and central Sweden. The soil was sampled down to 30cm soil depth in1984 /1986, 1993 and 2001. We report results on soil chemical changes and changes in base cation stores above and below ground. No significant positive effect on soil chemical status o

Nutrient uptake by forest trees is dependent on ectomycorrhizal (EM) mycelia that grow out into the soil from the mycorrhizal root tips. We estimated the production of EM mycelia in root free samples of pure spruce and mixed spruce-oak stands in southern Sweden as mycelia grown into sand-filled mesh bags placed at three different soil depths (0-10, 10-20 and 20-30 cm). The mesh bags were collected

Oxidized low-density lipoprotein (oxLDL) is known to induce apoptosis in endothelial cells, and this is believed to contribute to the progression of atherosclerosis. In the present study we made the novel observation that oxLDL-induced death of HMEC-1 cells is accompanied by activation of calpain. The mu-calpain inhibitor PD 151746 decreased oxLDL-induced cytotoxicity, whereas the general caspase

Mitochondria and chloroplasts are energy-transducing organelles of the cytoplasm of eukaryotic cells. They originated as bacterial symbionts whose host cells acquired respiration from the precursor of the mitochondrion, and oxygenic photosynthesis from the precursor of the chloroplast. The host cells also acquired genetic information from their symbionts, eventually incorporating much of it into t

The early B cell factor (EBF) is a transcription factor shown crucial for the development of B lymphocytes. The protein is expressed from the earliest stages of B cell development until the mature B cell stage, but the control elements responsible for the regulation of the gene are unknown. In this study, we report of the identification of a promoter region flanking the EBF gene. Several transcrip

The difficulties encountered in matching an antenna to its optimal impedance are reduced with an adaptive 0.35-mu m CMOS circuit based on several switched shunt capacitors arranged in capacitor banks and on a few external series inductors. As high-quality inductors are difficult to obtain in CMOS, the inductors are placed either in an low-temperature cofired ceramic (LTCC) substrate or is a lumped

The relation between the so called basis set superposition error and intramolecular vibrational frequencies calculated at the Hartree Fock SCF level of approximation was investigated. A linear conformation of HF dimer was chosen as test system for the investigation. It was found that the direct basis set superposition error for the studied system is rather small. It was further found that the shif

We examined the interaction of GABA and the competitive inhibitor SR95531 at human α1β1γ2S and α1β1 GABAA receptors expressed in Sf9 cells. The efficacy and potency of inhibition depended on the relative timing of the GABA and SR95531 applications. In saturating (10 mm) GABA, the half-inhibitory concentrations of SR95531 (IC50) when coapplied with GABA to α1β1γ2S or α1β1 receptors were 49 and 210

De samhälleliga förhållandena för personer med intellektuell funktionsnedsättning har under det senaste seklet utvecklats dramatiskt. Det förhållningssätt som under tidigare delen av 1900-talet ledde till institutionalisering och sterilisering har numera ersatts av ett förhållningssätt som i större utsträckning utgår från humanitet och ett bejakande av mänskliga rättigheter. Det moderna synsättet The societal conditions for individuals with intellectual disabilities have evolved dramatically over the past century. The approach that during the earlier parts of the 20th century led to practices such as institutionalization and sterilization has by now been replaced by an approach that to a higher extent is based upon the affirmation of basic human rights. This shift in approach has resulted

Inom matematik så används något som kallas derivator för att beräkna förändring. Ett exempel är hastighet som är positionens derivata. När man uppskattar hastighet så dividerar man förflyttningssträckan med tidsåtgången. För att ge en mer precis uppskattning för hastigheten i stunden så kan man då minska tiden man beräknar över. När detta görs på datorer så stöter man på problem när stegen blir föSome numerical methods approximate the Jacobian using finite differences as part of their process. The finite difference method of approximation resembles the limit definition of the derivative. Since a computer cannot handle the mathematical concept of limits, a sufficiently small number has to be chosen as an increment. However, when the increments are chosen outside of certain acceptable ranges

The main purpose of this project is to investigate and understand defense lawyers' use of dramaturgy and emotions during court proceedings, as well as how these strategies are employed in their collaboration with clients. Additionally, the project aims to examine the influence of status and power dynamics on defense lawyers' emotions and emotion management in court. The material comprises