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Wear mechanisms of uncoated and coated cemented carbide tools in machining lead-free silicon brass

Free-machining brass containing 2–3% of lead is a preferred industrial material as it shows excellent machinability where low cutting forces, short chips and reduced tool wear are attained. However this addition of lead, a highly toxic and hazardous material, leads to health and environmental issues. Alternative lead-free brasses are known for poor chip control and accelerated tool wear. The curre

Remissvar om promemorian "Byte av målvariabel och introduktion av variansband" från Lunds Universitet

Lunds universitet har uppmanats att lämna ett yttrande på rubricerad remiss. Universitet avger härmed följande synpunkter som utarbetats vid Ekonomihögskolan av docent Fredrik NG Andersson och professor emeritus Lars Jonung. Lars Jonung var medlem av Finanspolitiska Rådet och dess ordförande 2012-13.Lunds universitet välkomnar i stort de två förändringar av inflationsmålet som Riksbanken har föres

Child physical abuse – High school students’ mental health and parental relations depending on who perpetrated the abuse

The aim of this study was to contribute to the research of child physical abuse (CPA) by examining if there were any differences in high school students’ mental health (in this study symptoms of depression and anxiety, self-esteem and sense of coherence) and/or, in how they perceive their parents, depending on whether or not they had been subjected to CPA during childhood. In addition, if high sch

Socioeconomic Status and the Risk of Stroke Recurrence : Persisting Gaps Observed in a Nationwide Swedish Study 2001 to 2012

Background and Purpose-This nationwide observational study aimed to investigate how socioeconomic status is associated with risk of stroke recurrence and how possible associations change over time. Methods-This study included 168 295 patients, previously independent in activities of daily living, with a first-ever stroke in the Swedish Stroke Register (Riksstroke) 2001 to 2012. Riksstroke was link

Africa : Why Economists Got it Wrong

Not so long ago, Africa was being described as the ‘Hopeless Continent’. Recently, though, talk has turned to ‘Africa Rising’, with enthusiastic voices exclaiming the potential for economic growth across many of its countries. What, then, is the truth behind Africa’s growth, or lack of it?In this provocative book, Morten Jerven fundamentally reframes the debate, challenging mainstream accounts of

Statistical Tragedy in Africa?

What do we know about economic development in Africa? The answer is that we know much less than we would like to think. This collection assesses the knowledge problem present in statistics on poverty, agriculture, labour, education, health, and economic growth. While diverse in origin, the contributors to this book are unified in two conclusions: the quality and quantity of data needs to be improv

Cervical cancer risk perceptions, sexual risk behaviors and sexually transmitted infections among Bivalent Human Papillomavirus vaccinated and non-vaccinated young women in Uganda - 5 year follow up study

Background: Previous studies were conflicting regarding the associations between HPV vaccination, cervical cancer risk perceptions, high-risk sexual behaviors and STIs. This study compared the HPV-vaccinated and non-vaccinated young women in Uganda regarding cervical cancer risk perceptions, high-risk sexual behaviors, syphilis and HIV infections 5 years after vaccine implementation. Methods: This

Structural analysis and thermodynamics of the ionotropic glutamate receptor GluA2 modulator BPAM-97

Ionotropic glutamate receptors are tetrameric ligand gated ion channels that mediate in ux and ef ux of metal ions in response to glutamate. Positive allosteric modulators of the ionotropic glutamate receptor 2 (GluA2) are promising lead compounds for drugs against cognitive disorders. These compounds bind within the dimeric interface formed by the receptor ligand binding domains (LBDs) attenuatin

Evolution and forcing mechanisms of El Niño over the past 21,000 years

TheEl Niño SouthernOscillation(ENSO) isEarth's dominant source of interannual climate variability, but its response to globalwarming remainshighly uncertain1.To improve ourunder standing of ENSO's sensitivity to external climate forcing, it is paramount to determine its past behaviour by using palaeoclimate data and model simulations. Palaeoclimate records show that ENSO has varied considerably si

Close to the edge: growth restrained by the NAD(P)H/ATP formation flux ratio

Most fermentative microorganisms grow well-under anaerobic conditions managing a balanced redox and appropriate energy metabolism, but a few species do exist in which cells have to cope with inadequate energy recovery or capture and/or redox balancing. Two cases of these species, i.e., the metabolically engineered Saccharomyces cerevisiae enabling it to ferment xylose and Lactobacillus reuteri fer

Identification of sequence variants influencing immunoglobulin levels

Immunoglobulins are the effector molecules of the adaptive humoral immune system. In a genome-wide association study of 19,219 individuals, we found 38 new variants and replicated 5 known variants associating with IgA, IgG or IgM levels or with composite immunoglobulin traits, accounted for by 32 loci. Variants at these loci also affect the risk of autoimmune diseases and blood malignancies and in

Neutrophil Trafficking in Pulmonary Inflammation: Monitoring Migration and Blockade with 111In-Labeled Leukocytes

AbstractAim: Although imaging of In vitro labeled leukocytes is commonly used for diagnosing inflammation and infection, data concerning the use of this technique to monitor neutrophil trafficking are scarce. Here we investigated thepotential of 111In-in vitro labeled leukocytes (InWBC) to monitor neutrophil trafficking in an animal model of pulmonary inflammation.Methods: F344 rats were divided i