Total Marrow Irradiation (TMI) with Helical Tomotherapy is a radiotherapy treatment technique that targets bone marrow and sanctuary sites prior to stem cell or bone marrow transplantation (SCT/BMT). TMI is a complex procedure that involves several critical steps that all need to be carefully addressed for a successful implementation, such as dose homogeneity in field junctions, choice of target m

Phosphatocopids are a group of small extinct marine crustaceans, which occur widespread in Cambrian dysoxic benthic lithofacies. Whereas the anatomy of the earliest ontogenetic stages of phosphatocopids, from the head larva with four pairs of appendages onward, is well documented, that of more advanced or adult growth stages has remained almost unknown (except for the external shields). Here we de

In the current chapter two semiconductor materials are being assessed as ecomaterials of choice for key applications in the water business. Ultraviolet lightemitting diodes, UV-LEDs, based on III-Nitride ultraviolet emitters like GaN, InGaN, and AlGaN and semiconductor oxides like TiO 2 , ZnO, or WO 3 can be used as eco-materials for disinfection and pollutant removal in water, respectively. Lo

Objectives: The aim of this study was to evaluate the effect of fractional flow reserve (FFR)–guided revascularization compared with culprit-only percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) on infarct size, left ventricular (LV), function, LV remodeling, and the presence of nonculprit infarctions. Background: Patients with STEMI with

Urban pedestrian-level air quality is a result of an interplay between turbulent dispersion conditions, background concentrations, and heterogeneous local emissions of air pollutants and their transformation processes. Still, the complexity of these interactions cannot be resolved by the commonly used air quality models. By embedding the sectional aerosol module SALSA2.0 into the large-eddy simula

In forensic DNA analysis, the polymerase chain reaction (PCR) enables DNAanalysis of minute biological crime scene traces. PCR is an enzymatic reaction for amplification of specific DNA fragments involving both biochemical andbiophysical processes. The main analytical challenge is posed by the nature of the samples of interest. Crime scene samples are heterogeneous and often contain background mat

The temperature dependence of the conformational properties in simulations of the intrinsically disordered model protein histatin 5 has been investigated using different combinations of force fields, water models, and atomistic and coarse-grained methods. The results have been compared to experimental data obtained from NMR, SAXS, and CD experiments to assess the accuracy and validity of the simul

For many multivariable problems there are no efficient algorithms for finding solutions. To this day, conventional electronic computers mainly solve problems in a sequential manner. This sequential operation prevents problem-solving within a reasonable time-frame due to superpolynomial, and sometimes even exponential, time complexities. Developing powerful parallel computation techniques has there

What role does academic development have to play in responding to radical cultural shifts in the global landscape? Whose voices and identities are contributing to institutional change? This reflective essay encompasses the perspectives of the four international panellists in the opening plenary of the International Consortium for Educational Development (ICED) 2018 conference in Atlanta, Georgia,

A measurement of the four-lepton invariant mass spectrum is made with the ATLAS detector, using an integrated luminosity of 36.1 fb −1 of proton-proton collisions at s = 13 TeV delivered by the Large Hadron Collider. The differential cross-section is measured for events containing two same-flavour opposite-sign lepton pairs. It exhibits a rich structure, with different mass regions dominated in th

WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Technology for cardiac output (CO) and blood volume measurements has been developed based on blood dilution with a small bolus of physiologic body temperature saline, which, after transcardiopulmonary mixing, is detected with ultrasound sensors attached to an extracorporeal arteriovenous loop using existing

The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a multi-ancestry genome-wide gene–smoking interaction study in 133,805 individuals with follow-up in an additional 253,467 individuals. Combined meta-analyses identified 13 new loci assoc

We compared three different Graphical User Interfaces (GUI) that we have designed and implemented to enable human supervision of an unmanned ship. Our findings indicate that a 3D GUI presented either on a screen or in a Virtual Reality (VR) setting provides several objective and subjective benefits compared to a Baseline GUI representing traditional tools.

We have calculated the decay rates of the Bs meson in a number of exclusive two-body decay channels using the Bauer-Stech-Wirbel model for current matrix elements. The influence of the free parameters of the model on the predictions is studied. The total branching ratio of the Bs into final states which only contain stable particles is found to be about 10-3.

Purpose: To evaluate the potential for right ventricular reverse remodelling after pulmonary valve replacement using cardiac magnetic resonance imaging, in adults with corrected tetralogy of Fallot and severe pulmonary insufficiency. Material and methods: Ten patients with previous correction of tetralogy of Fallot with severe pulmonary insufficiency accepted for pulmonary valve replacement were