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Den ädle terroristen

Om mannen som försökte döda Adolf Hitler 1944, Claus Schenk von Stauffenberg i tysk historieskrivning och amerikansk filmtradition

Is weight loss beneficial for reduction of morbidity and mortality? What is the controversy about?

The increase of obesity and type 2 diabetes on a global scale has increased the interest in how to counteract this epidemic. Improved lifestyle in general is a fundamental approach, but other remedies such as specific weight reduction or diabetes preventive drugs and surgery have also been tested. One problem to understand is what really happens after weight loss. Ongoing studies will try to addre

Serum Insulin-Like Growth Factor-I Concentration Is Associated with Leukocyte Telomere Length in a Population-Based Cohort of Elderly Men.

Context: Both leukocyte telomere length and IGF-I are associated with the aging process. A previous in vitro study suggested that IGF-I may modulate telomerase activity in white blood cells, but little is known whether these two systems interact in vivo. Patients and Methods: Leukocyte telomere length was determined using a quantitative PCR assay in 2744 elderly men (mean age 75.5 yr, range 69-81

Heart Rate Estimation from Dual Pressure Sensors of a Dialysis Machine

Dialysis patients often suffer from cardiovascular dis- eases, motivating the use of continuous monitoring of car- diac activity in clinical routine. Cardiac pressure pulses propagate through the vascular system and enter the ex- tracorporeal blood circuit of a dialysis machine, where the pulses are captured by pressure sensors. The cardiac pulses are obscured by the much stronger pressure pulses

Genetic loci for bone architecture determined by three-dimensional CT in crosses with the diabetic GK rat.

The F344 rat carries alleles contributing to bone fragility while the GK rat spontaneously develops type-2 diabetes. These characteristics make F344xGK crosses well suited for the identification of genes related to bone size and allow for future investigation on the association with type-2 diabetes. The aim of this study was to identify quantitative trait loci (QTLs) for bone size phenotypes measu

Laparoscopic aided cholecystostomy as a treatment of inspissated bile syndrome.

We report a case of a newborn girl with inspissated bile syndrome (IBS) that did not respond to treatment with oral ursodeoxycholic acid (Ursofalk). A solution was found using laparoscopic aided cholecystostomy with an indwelling catheter for local Ursofalk flushing in the gallbladder and the choledochus. This is the first report of a laparoscopic aided management of IBS without cholecystectomy or

Tree species composition in European pristine forests

The degree of general applicability across Europe currently achieved with several forest succession models is assessed, data needs and steps for further model development are identified and the role physiology based models can play in this process is evaluated. To this end, six forest succession models (DISCFORM, ForClim, FORSKA-M, GUESS, PICUS v1.2, SIERRA) are applied to simulate stand structure

A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival.

Summary The haematopoietic growth factor receptor Flt3 has been implicated as major cause of transformation in acute myeloid leukaemia. Intracellular signals mediated by wild-type Flt3 are involved in cell differentiation and survival whereas signalling via the mutant Flt3 ITD (internal tandem duplication) promotes enhanced cell growth. In this study, we identified tyrosines 768, 955 and 969 of Fl

ICT DEVELOPMENT STRATEGIES FOR INDUSTRIALISATION OF THE BUILDING SECTOR

The article presents the main results of a joint investigation by Swedish researchers and industry representatives carried out during 2006-2007 concerning the benefits of modern object based information and communication technology, ICT, for industrialisation of the building industry. The background for the investigation was an experience by both parties of a lack of coherence between scientific r

Prednisolone in Bell's Palsy Related to Treatment Start and Age.

OBJECTIVE:: To evaluate if treatment start and age are related to the outcome in Bell's palsy patients treated with prednisolone. STUDY DESIGN:: Prospective, randomized, double-blind, placebo-controlled, multicenter trial. SETTING:: Sixteen otorhinolaryngologic centers in Sweden and 1 in Finland. PATIENTS:: Data were collected from the Scandinavian Bell's palsy study. A total of 829 patients were

Product modelling of configurable building systems - a case study

This paper investigates a Swedish house manufactures building system regarding the documentation and information structures. The aim is to evaluate how product modeling technology can be used to facilitate product customization. By dividing the product in four different views the complexity of the product can be reduced and each view represent the interest of customer, engineering, production and

Economic perspectives on the obesity epidemic

Popular Abstract in Swedish Den här avhandlingen tar sin utgångspunkt i de omfattande ökningarna i övervikt och fetma som har observerats, och blivit ett stort folkhälsoproblem, runtom i världen, och som har kommit att benämnas fetma-epidemi. Det inledande kapitlet motiverar att fetma studeras från ekonomiska perspektiv och ger en bakgrund till de efterföljande kapitlen. Därefter följer fyra fristThis thesis takes its starting point in the large spread and rise in obesity prevalence that have been observed around the world, making obesity an increasing public health concern. The thesis consists of an introductory chapter, which justifies the study of obesity from economic perspectives and puts the subsequent studies in context, and four studies that address obesity from different economic

Characterisation of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumours.

Amplification of chromosomal region 11q13, containing the cell cycle regulatory gene CCND1, is frequently found in breast cancer and other malignancies. It is associated with the favourable oestrogen receptor (ER)-positive breast tumour phenotype, but also with poor prognosis and treatment failure. 11q13 spans almost 14 Mb and contains more than 200 genes and is affected by various patterns of cop