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Low molecular weight protein tyrosine phosphatase (LMW-PTP) dimerizes in the phosphate-bound state in solution with a dissociation constant of K-d = 1.5(+/-0.1) mM and an off-rate on the order of 10(4) s(-1).H-1 and N-15 NMR chemical shifts identify the dimer interface, which is in excellent agreement with that observed in the crystal structure of the dimeric S19A mutant. Two tyrosine residues of

In 44 consecutive patients with systemic sclerosis (SSc), plasma concentrations of von Willebrand factor (vWf) were higher than those of the vWf propeptide, but the propeptide showed less variability within patient subgroups. Higher values of the propeptide were observed in patients with early pulmonary involvement. A closer correlation of the propeptide than of vWf to biochemical markers of activ

Artikel om laserskivans betydelse för den tekniska reproduktionen av film och om betydelsen av tillgängligheten av extramaterial för filmforskningen.

Heating equimolar mixtures of Sb2O3 and V2O5 at 800 degrees C in flowing gas with varying O-2/N-2 ratios produces a continuous nonstoichiometric series of rutile type, i.e., Sb(0.9)V(0.9+x)square(0.2-x)O(4), 0 < x < 0.2, and varying amounts of alpha-Sb2O4. Oxidized Sb(0.9)V(0.9)square(0.2)O(4), a = 4.63, c = 3.03 Angstrom (X ray powder data, XRD), is formed in pure oxygen and exhibits a modulated

Supported lipid membranes are particularly attractive for use in biochemical assays because of their resistance to nonspecific adsorption and their unique ability to host transmembrane proteins. Although ideal for use in many surface-based detection techniques, supported bilayers can make the incorporation of proteins problematic due to the steric constraints of the underlying substrate. A recentl

Both spring temperature and date of the first Starling Sturnus vulgaris egg were highly correlated between different study sites and weather stations in the southern half of Sweden. In southern Sweden, but not in northern Sweden, onset of breeding correlated strongly with spring temperature, particularly during the last ten days of April, the period that happens to coincide with the start of breed

This paper describes a methodology for measuring theological flow properties in-line, in real-time, based on simultaneous measurements of velocity profiles using an ultrasound velocity profiling (UVP) technique with pressure difference (PD) technology. The methodology allows measurements that are rapid, non-destructive and non-invasive and has several advantages over methods presented previously.

The purpose of this study is to contrast the forecasting performance of two non-linear models, a regime-switching vector autoregressive model (RS-VAR) and a recurrent neural network (RNN), to that of a linear benchmark VAR model. Our specific forecasting experiment is U.K. inflation and we utilize monthly data from 1969 to 2003. The RS-VAR and the RNN perform approximately on par over both monthly

Sixty-seven patients (45 males and 22 females) aged 2 to 70 years (mean 36 years) who had suffered closed head injury were investigated with daily transcranial Doppler (TCD) recordings. A total of 470 TCD recordings (mean 7) were made during Days 1 to 14 after admission. Blood flow velocities were determined in the middle cerebral artery (MCA) and the extracranial internal carotid artery (ICA). Tw

In this dissertation, I have studied Native North American reservations and why they still exist. My research was carried out with the Ojibway, Lakota and Métis peoples in the Midwestern region of the USA and Canada. I chose three reservations with public radio facilities and one reserve community without radio in order to complete this investigation. Also, I have examined and described the Powwow

PURPOSE: Substantial controversy exists in the literature regarding the association between pretreatment testosterone and disease outcome in patients with prostate cancer. We explored the relationship between preoperative total testosterone, and pathological stage and progression in patients with clinically localized prostate cancer treated with radical prostatectomy. MATERIALS AND METHODS: We ret

Medical geography usually attempts to disentangle and explain the ecological and causal contexts of health, disease and environment by mapping spatial patterns of cases and potential pathogenic factors. However, many diseases are believed to show after long periods of latency , spanning years and even decades between initial exposure and clinical onset. In view of high spatial human mobility - in

Popular Abstract in Swedish Många beständighetsproblem uppträder i gränsytor mellan material. Exempel är lossfrysning av puts på tegel, avflagning av färg, sprickbildning hos ytskikt, vidhäftningsbrott mellan reparationsmaterial och underlag. I nästan alla fall är nedbrytningen kopplad till alltför höga fuktnivåer i gränsytan. Flera beständighetsproblem, t.ex. frostnedbrytning, uppstår enbart om mThe main impetus for this research was the desire to verify models for determining transient moisture profiles in the capillary range. For the evaluations, transient moisture profiles were both simulated and measured, after which the results of the two methods were compared. The study was performed for on specimens exposed to continuous water absorption, using specimens of both single and combined