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The underlying molecular mechanisms in osteoarthritis (OA) development are largely unknown. This study explores the proteome and the pairwise interplay of proteins in synovial fluid from patients with late-stage knee OA (arthroplasty), early knee OA (arthroscopy due to degenerative meniscal tear) and from deceased controls without knee OA.Synovial fluid samples were analyzed using state-of-the-art

In the recent Internet-of-Things (IoT) era where biomedical applications require continuous monitoring of relevant data, edge computing keeps gaining more and more importance. These new architectures for edge computing include multi-core and parallel computing capabilities that can enable prevention diagnosis and treatment of diseases in ambulatory or home-based setups. In this article, we explore

Low-power wearable technologies offer a promising solution to pervasive epilepsy monitoring by removing the constraints concerning time and location, on one hand, and fulfilling long-term tracking, on the other hand. In the case of epileptic seizures, as the attacks infrequently occur, using an anomaly detection approach reduces the need to record long hours of data for each patient before detecti

It is well known that event-triggered and self-triggered controllers implemented on dedicated platforms can provide the same performance as the traditional periodic controllers, while consuming considerably less bandwidth. However, since the majority of controllers are implemented by software tasks on shared platforms, on one hand, it might no longer be possible to grant access to the event-trigge

I februari 2001 var det stort pådrag i AF-borgen i Lund. Det europeiska språkårets öppningskonferens invigdes och 250 EU-delegater och lika många åhörare samlades för att manifestera vikten av språklig mångfald i Europa. Alla var där, men allt var inte klang och jubel. Konferensen hade rubriken ”Språklig mångfald i Europa – en utmaning” och dagarna före invigningen publicerades en undersökning där

The text describes new methods elaborated for and used in the building archaeological assessment of a city block, studied first on site, then remotely by members of the Swedish Pompeii Project. Use of a digital platform, with collected wall observations and analysis, systematic photographic documentation of all standing structures, and 3D models, allowed discussion to proceed after the fieldwork c

Background: Symptomatic osteoarthritis of the basal joint of the thumb (trapeziometacarpal joint) is a common disabling condition mainly affecting women. It is frequently treated with complete removal of the trapezium with or without soft-tissue interposition. There is limited evidence about whether removal of the trapezium affects stability of the wrist joint and increases the risk of developing

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from biobank archives were directly analyzed using simple sample preparation. WiMT is based on MS1 features between several MS runs together with custom prote

An electric road system (ERS) enables transfer of electric energy to a moving vehicle, making it possible to reduce the capacity—and cost—of the battery and the need for static chargers. A conductive electric road allows for relatively low complexity whilst being able to provide high levels of power. When utilising a conductive electric road, safety precautions must be considered with regard to is

The refugee crisis is also a crisis in education. While attention is frequently directed toward primary and secondary school levels, higher education is a strategic issue for refugees, both as individuals and for long term processes of post-conflict recovery and peacebuilding. Education prospects and content are drivers of onwards migration, but also affect economic structures on return. Higher ed

The propensity to kill and consume conspecifics (cannibalism) varies greatly between and within species, but the underlying mechanisms behind this variation remain poorly understood. A rich literature has documented that consistent behavioural variation is ubiquitous across the animal kingdom. Such inter-individual behavioural differences, sometimes referred to as personality traits, may have far-

There is a great need to find cheaper but still efficient treatment methods for wastewater. This study aimed to test the purifying performance of three different Moringa oleifera varieties that were cultivated in Tunisia on raw (RUW) and secondary treated urban wastewater (TUW). The seeds of the Mornag, Egyptian, and Indian varieties were powdered, added to the water (at concentrations of 0, 50, 1

Introduction: The development of inhibitory antibodies is a severe complication of clotting factor replacement therapy in patients with severe haemophilia A (HA). Current World Federation of Hemophilia (WFH) guidelines for haemophilia care indicate that eradication of inhibitors is best achieved through immune tolerance induction (ITI) therapy. Aim: The European Collaborative Haemophilia Network c