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Epigenetic and Phenotypic Profiling of Urothelial Carcinoma

Popular Abstract in Swedish Epigenetik handlar om hur avläsning av informationen i arvsmassan kan styras och nedärvas mellan cellgenerationer. Förmågan att kunna ändra genuttrycksmönster som svar på signaler från omgivningen och sedan bibehålla dessa genom efterföljande celldelningar ligger till grund för korrekt funktion av vävnaderna och organen som våra kroppar är uppbyggda av. Samtliga sjukdomPrecise spatial and temporal regulation of gene expression programs is a prerequisite for multicellular life. Since the discovery of DNA as the carrier of genetic information, a key question in biology has been how these hard coded instructions are read and regulated to maintain cellular and organismal homeostasis. Understanding the mechanisms and processes governing gene and genome regulation are

Tissue Ingrowth Into Foam but Not Into Gauze During Negative Pressure Wound Therapy

Background. Foam and gauze are two types of wound fillers used for negative pressure wound therapy (NPWT). Differences in the wound healing effects of foam and gauze have been observed clinically. The aim of the present study was to examine the effects of NPWT on the wound bed using foam and gauze. Methods. A porcine peripheral wound model was treated with NPWT at 0, -75 mmHg, or -125 mmHg for 72

fUML Activity Diagrams with RAG-controlled Rewriting: A RACR Solution of The TTC 2015 Model Execution Case

This paper summarises a RACR solution of The TTC 2015 Model Execution Case. RACR is a metacompiler library for Scheme. Its most distinguished feature is the seamless combination of reference attribute grammars and graph rewriting combined with incremental evaluation semantics. The presented solution sketches how these integrated analyses and rewriting facilities are used to transform fUML Activity

Late Holocene and modern glacier changes in the marginal zone of Solheimajokull, South Iceland

The forefield of the Solheimajokull outlet glacier, South Iceland, has a variety of glacial landforms and sediments that are products of late Holocene and modern glacier oscillations. Several sets of moraine ridges reflect past ice front positions and river-cut sedimentary sections provide information about past environments. Here, we describe sediments and landforms deposited during the late Holo

Pd2Cd11-delta (0.21

The Cd rich part of the Cd-Pd phase diagram was reassessed by means of synthesis and single crystal and powder X-ray diffraction. The region contains two phases that have been reported to have substantial compositional widths, Cd11Pd2 and Cd4Pd. The phase Cd11Pd2 that has previously been reported to be a disordered gamma-brass crystallizing is space group P (4) over bar 3m is here shown to crystal

Using geographical information systems to analyse accessibility to health services in the West Bank, Occupied Palestinian Territory

Abstract in UndeterminedAccessibility to adequate health services is a basic human right. Israeli road blocks and checkpoints inhibit access to health care for the Palestinian population. While other studies have dealt with the impact of the barriers, few are based on actual measurements of transport times between locations. Geographical information systems (GIS) and network analysis were used to

Effects of drought conditions on the carbon dioxide dynamics in a temperate peatland

Drought is arguably the most important regulator of inter-annual variation in net ecosystem CO2 exchange (NEE) in peatlands. This study investigates effects of drought periods on NEE and its components, gross primary production (GPP) and ecosystem respiration (R-eco), on the basis of eddy covariance measurements of land-atmosphere exchange of CO2 in 2006-2009 in a south Swedish nutrient-poor peatl

On strong Hellinger consistency of posterior distributions

We establish a sufficient condition ensuring strong Hellinger consistency of posterior distributions. We also prove a strong Hellinger consistency theorem for the pseudoposterior distributions based on the likelihood ratio with power 0 < alpha < 1, which are introduced by Walker and Hjort [2001 'On Bayesian Consistency', J. R. Statist. Soc., B 63, 811-821]. Our result is an extension of their theo

Functionalised ZnO-nanorod-based selective electrochemical sensor for intracellular glucose

In this article, we report a functionalised ZnO-nanorod-based selective electrochemical sensor for intracellular glucose. To adjust the sensor for intracellular glucose measurements, we grew hexagonal ZnO nanorods on the tip of a silver-covered borosilicate glass capillary (0.7 mu m diameter) and coated them with the enzyme glucose oxidase. The enzyme-coated ZnO nanorods exhibited a glucose-depend

Neutral pion production at midrapidity in pp and Pb-Pb collisions at root(NN)-N-S=2.76 TeV

Invariant yields of neutral pions at midrapidity in the transverse momentum range 0.6 < pT < 12 GeV/c measured in Pb-Pb collisions at root(NN)-N-s = 2.76 TeV are presented for six centrality classes. The pp reference spectrum was measured in the range 0.4 < pT < 10 GeV/c at the same center-of-mass energy. The nuclear modification factor, R-AA, shows a suppression of neutral pions in central Pb-Pb