Infections frequently consist of more than one strain of a given pathogen. Experiments have shown that co-infecting strains often compete, so that the infection intensity of each strain in mixed infections is lower than in single strain infections. Such within-host competition can have important epidemiological and evolutionary consequences. However, the extent of competition has rarely been inves

Leptin has been shown to play an integral role in the endocrine regulation of metabolism. Moreover, a substantial amount of this peptide has been found in colostrum and milk. The aim of the study was to investigate the effects of exogenous leptin, administered intragastrically, on the process of autophagy and the changes in cell hyperplasia and hypertrophy in the small intestine mucosa. Three grou

Abstract: This thesis consists of four papers related to various aspects of steady water waves. Paper I: Deep-water waves with vorticity: symmetry and rotational behaviour. We show that for steady, periodic, and rotational gravity deep-water waves, a monotone surface profile between troughs and crests implies symmetry. It is observed that if the vorticity function has a bounded derivative, the

The present study was designed to delineate the presence of COMP at the ultrastructural level comparing concentrations between two areas of articular cartilage from the equine third carpal bone, subjected to different loading, from trained and untrained horses. We also analyzed the fibril thickness of collagen type II in the same compartments and zones. Samples were collected from high load-bearin

Nonlamellar lipid liquid crystalline (LC) bulk phases and dispersions show promise as functional nanostructured materials for potential use as controlled release matrices e. g. in pharmaceuticals. Herein, methods for preparing and characterizing thin films of lipid liquid crystalline phases on solid surfaces are presented. The thickness, hydration phase structure and surface topography of spin-coa

Background - There are numbers of persons living in the community with late effects of polio, of which many develop new symptoms, but the course of progression is unclear. Objectives - To assess changes after 4 years in ability and perceived difficulty in persons with late effects of polio. Material and methods - Community dwelling persons from a polio clinic. Information was gathered by questionn

Web-based civic participation in democracies, especially in the sprawling domain of alternative politics, continues to grow. In this paper I explore the intersection of two trajectories of such participation: one that takes the form of journalism (broadly understood) and the other that is transnational in character. Participatory journalism unavoidably evokes normative issues that professional jou

Popular Abstract in English Each year an estimated 530 000 new cases of cervical cancer are diagnosed and more than 275 000 women die from cervical cancer worldwide (2). Cervical cancer is caused by sexually-acquired infections with a subset of human papillomavirus (HPV) (359, 360). HPV is the most common viral infection of the anogenital tract (2). Almost all sexually active individuals will be iHuman papillomaviruses (HPVs) cause almost half of the human cancers that are attributable to viruses. HPV type 16 is the most carcinogenic type among the HPVs and is detected in 50% of all cervical cancers. HPV-16 infects epithelial cells and HPV-16 gene expression is tightly linked to the differentiation stage of the infected cells. Early HPV-16 genes are expressed in basal layers of the epithel

Recension av boken: Problemet utan namn? : neuroser, stress och kön i Sverige från 1950 till 1980. Författare: Maria Björk 2011. Uppsala: ActaUniversitatis Upsaliensis. Uppsala Studies in History of Ideas 43. 306 s. ISBN 978-91-554-8079-0.

While intercellular communication processes are frequently characterized by switch-like transitions, the endocrine system, including the adipose tissue response to insulin, has been characterized by graded responses. Yet here individual cells from adipose tissue biopsies are best described by a switch-like transition between the basal and insulin-stimulated states for the trafficking of the glucos

Transient heat and mass transport in a wall-cooled tubular catalytic bed reactor is numerically investigated. A two-dimensional pseudo-heterogeneous model, accounting for transport in the solid and fluid phases, with axial and radial dispersions is used to describe transport in the reactor. The effects of inlet process conditions, viz., temperature and concentration, are investigated and their imp

The electric power grid contains more and more renewable power production such as wind and solar power. The use of renewable power sources increases the fluctuations in the power grid which increase the demand for highly efficient, fast-starting power-producing units that can cope with sudden production losses. One of the more innovative power plant cycles, that have the potential of competing wit

Background: Metastatic prostate cancer is associated with a high morbidity and mortality but the spreading mechanisms are still poorly understood. The aminobisphosphonate alendronate, used to reduce bone loss, has also been shown to inhibit the invasion and migration of prostate cancer cells in vitro. We used a modified orthotopic PC-3 nude mouse tumor model of human prostate cancer to study wheth

Background: Acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are common early-onset malignancies. Their causes are largely unknown but infectious etiology has been implicated. Type 1 diabetes (T1D) is an autoimmune disease for which infectious triggers of disease onset have been sought and increasing pointing to enteroviruses. Based on our previous results on co-morbidity betwee

Aim. The aim was to explore opinions on individual needs and other factors that may influence nursing staff turnover. Background. High staff turnover is a great problem for many hospitals. It is shown to have a negative effect on the quality of nursing care and to increase hospital costs. Design. In 2004 in a large university hospital in Sweden five focus group discussions (FGDs) including departm

Ischemic stroke, resulting from occlusion of a brain artery is the most common type of stroke with a prevalence of 15 million people and the leading cause of long-term disability worldwide. Importantly, partial spontaneous recovery of lost neurological functions occurs mainly during the first months after stroke onset, albeit to a limited extent. Recovery has been attributed to mechanisms of compe

A search for the Standard Model Higgs boson in proton-proton collisions with the ATLAS detector at the LHC is presented. The datasets used correspond to integrated luminosities of approximately 4.8 fb(-1) collected at, root s = 7 TeV in 2011 and 5.8 fb(-1) at root s = 8 TeV in 2012. Individual searches in the channels H -> ZZ(()*()) -> 4l, H -> gamma gamma and H -> WW (()*()) -> ev mu v in the 8 T