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Strategic implementation of circular business models in developing countries

This thesis aims to address the challenges of implementing circular economy (CE) practices in emerging/developing economies by harnessing the resources of multinational corporations (MNCs) to improve waste management situations in these areas of the world. A case study is conducted on a Swedish beverage carton producer operating in Thailand to examine the key challenges and strategies employed by

Surgical outcomes of gallbladder cancer: the OMEGA retrospective, multicentre, international cohort study

Background: Gallbladder cancer (GBC) is rare but aggressive. The extent of surgical intervention for different GBC stages is non-uniform, ranging from cholecystectomy alone to extended resections including major hepatectomy, resection of adjacent organs and routine extrahepatic bile duct resection (EBDR). Robust evidence here is lacking, however, and survival benefit poorly defined. This study ass

Growth and electronic properties of epitaxial TiN thin films on 3C-SiC(001) and 6H-SiC(0001) substrates by reactive magnetron sputtering

Epitaxial TiN films were grown on cubic (3C)-SiC(001) and hexagonal (6H)-SiC(0001) substrates by ultrahigh vacuum reactive magnetron sputtering from a Ti target in a mixed Ar and N2 discharge at a substrate temperature of 700°C. Cross-sectional transmission electron microscopy, including high-resolution imaging, showed orientational relationships TiN(001) ∥ 3C-SiC(001), and TiN[110] ∥ 3C-SiC[110],

Serving Danish Foreign Policy : Andreas Hojer’s De eo quod iure belli licet in minores (1735)

This chapter discusses the inaugural dissertation of the first ex officio professor of natural law in Denmark, Andreas Hojer: the 1735 Dissertatio iuris publici universalis de eo quod iure belli licet in minores. In doing so, it seeks to shed light on a little-known figure in the early Danish enlightenment, albeit one who was very influential in his day. It explains why Hojer chose what, on the fa

The Law of Nations

This chapter gives an account of Pufendorf’s discussion and use of the law of nations. It first outlines his distinctive contribution to contemporary discussions of the topic, namely his rejection rejection, against Grotius, of a specific “positive” law of nations distinct from the law of nature. Secondly it explains how this position relied on Pufendorf’s voluntarist conception of law as the comm

A Humanist in Reformation Politics : Philipp Melanchthon on Political Philosophy and Natural Law

This book is the first contextual account of the political philosophy and natural law theory of the German reformer Philipp Melanchthon (1497-1560). Mads Langballe Jensen presents Melanchthon as a significant political thinker in his own right and an engaged scholar drawing on the intellectual arsenal of renaissance humanism to develop a new Protestant political philosophy. As such, he also shows

Dietary pesticide exposure and non-communicable diseases and mortality: a systematic review of prospective studies among adults

BackgroundResearch on the effect of pesticide exposure on health has been largely focused on occupational settings. Few reviews have synthesized the associations between dietary pesticide exposure and health outcomes in non-occupationally exposed adults.ObjectiveWe aim to summarize the evidence regarding dietary pesticide exposure and non-communicable diseases (NCD) in adults, using a systematic r

LexVEN: A quick vocabulary test for proficiency in Venetan

While there is growing awareness that knowledge of regional minority languages must be protected, assessing the vitality of such varieties is challenging due to the lack of assessment materials. Our contribution documents the creation and validation of LexVEN, a bimodal yes/no vocabulary task, with the purpose of assessing the proficiency of users of Venetan with receptive and/or productive skills

Identifying actionable druggable targets for breast cancer : Mendelian randomization and population-based analyses

Background: Drug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR) and then validate the candidate drugs using population-based analyses. Methods: We identified genetic instruments for 1406 actionable targets of approved non-oncological drugs based on

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Résumé Français: Si l’écriture inclusive polarise largement l’opinion publique, les causes exactes des réticences envers son usage ne sont pas toujours très claires. Nous explorons les liens entre les attitudes envers l’écriture inclusive et différents facteurs, comme le niveau de connaissance linguistique ou historique de l’écriture inclusive. Nous avons également mesuré l’orientation politique dAlthough gender inclusive writing is widely polarised in public opinion, the exact causes of reluctance towards its use are not always clear. We explore the link between attitudes towards inclusive writing and different factors, such as the level of linguistic or historical knowledge of inclusive writing. We also measured the political orientation of the respondents, as well as their views on the

A Cautionary Note on "a Cautionary Note on the Use of Ornstein Uhlenbeck Models in Macroevolutionary Studies"

Models based on the Ornstein-Uhlenbeck process have become standard for the comparative study of adaptation. Cooper et al. (2016) have cast doubt on this practice by claiming statistical problems with fitting Ornstein-Uhlenbeck models to comparative data. Specifically, they claim that statistical tests of Brownian motion may have too high Type I error rates and that such error rates are exacerbate

MHCCL : Masked Hierarchical Cluster-Wise Contrastive Learning for Multivariate Time Series

Learning semantic-rich representations from raw unlabeled time series data is critical for downstream tasks such as classification and forecasting. Contrastive learning has recently shown its promising representation learning capability in the absence of expert annotations. However, existing contrastive approaches generally treat each instance independently, which leads to false negative pairs tha

Homocysteine accelerates hepatocyte autophagy by upregulating TFEB via DNMT3b-mediated DNA hypomethylation

Autophagy plays a critical role in the physiology and pathophysiology of hepatocytes. High level of homocysteine (Hcy) promotes autophagy in hepatocytes, but the underlying mechanism is still unknown. Here, we investigate the relationship between Hcy-induced autophagy level and the expression of nuclear transcription factor EB (TFEB). The results show that Hcy-induced autophagy level is mediated b