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Negative prognostic impact of tumor deposits in rectal cancer – a national study cohort

Objective: To investigate whether tumor deposits (TDs) in rectal cancer are associated withincreased recurrence risk and decreased survival.Summary background data: Tumor deposits (TDs) are considered a risk factor forrecurrence after colon cancer resection and presence of TDs prompts adjuvant chemotherapy.The prognostic relevance of TDs in rectal cancer requires further exploration.Methods: All p

Analys av varmvattenbehov i äldreboenden för möjliggörande av god inomhuskomfort

I Särskilda boende för äldre (SÄBO) vistas både boende i sin bostad och personal som har boendet somsin arbetsplats. Det är viktigt att SÄBO utformas energieffektivt och på ett sätt som möjliggör att bådagrupperna får en god inomhusmiljö. De regelverk som finns tillgängliga för att åstadkomma detta, bådeavseende inomhusmiljö och energianvändning för varmvatten, skiljer sig åt mellan boende ocharbe

What does ASEAN Economic Community bring to older workers? Examining inequality in old age in Thailand’s fast-ageing society

The ASEAN Economic Community is envisaged to promote economic integration initiatives to create a single market across Southeast Asian member countries. It is acknowledged that the intergovernmental initiatives need to be accommodative to national and regional contexts. Thailand, as a pivotal and active partnership, endeavors to facilitate economic transformation and regional integration within th

Portrayal of life stages on Swedish municipal media: a life course perspective

Media portrayal of older adults is an expression of social realities and expectations, and the image of ageing has significant implications for intergenerational relations. A life course perspective is suggested for viewing old age as the final stage of successive lifespan development and investigating the social meaning of old age through comparisons of life stages. This article focuses on the vi

Ageism in the media : online representations of older people

Ageism is a social problem that has harmful effects on the wellbeing of older people and needs to be tackled. It is pervasive and evident in the media (e.g., films, television, print and social media). Despite the fact that non-individual actors have adopted social media on a large scale in contemporary society, the social media representation of older people generated by those actors has remained

Optimising conditions and environments for digital participation in later life: a macro-meso-micro framework of partnership-building

The ongoing digitalisation of societies, exacerbated by the COVID-19 pandemic, has led to increased efforts to ensure the digital inclusion of older adults. Digital inclusion strategies throughout the COVID-19 pandemic predominantly focused on increasing access and basic digital literacy of Information and Communication Technologies (ICTs) for all members of society. Older adults, who are more lik

Promoting healthy ageing in the Western Pacific: a mini review of good practices and policy responses

The Western Pacific Region is experiencing rapid population ageing, which has implications for almost all areas of society. Countries will need to prepare for population ageing by investing in health and optimizing living environments. This requires a whole-of-society approach to healthy ageing. Countries in the Western Pacific Region have been making significant progress in healthy ageing. Since

Meningioma microstructure assessed by diffusion MRI : An investigation of the source of mean diffusivity and fractional anisotropy by quantitative histology

BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in

Other syndromes of orthostatic intolerance : Delayed orthostatic hypotension, postprandial hypotension, postural orthostatic tachycardia syndrome, and reflex syncope

Apart from classical orthostatic hypotension, the gravitational force may strongly contribute to other forms of orthostatic intolerance, delayed and postprandial OH, postural orthostatic tachycardia syndrome (POTS), and reflex syncope. In delayed OH, the significant blood pressure drop occurs first after 3-min period of orthostasis, whereas in postprandial OH, the symptoms appear first approximate

New Targeted Interest Deduction Limitation Rules Post Lexel

Both the European Union (EU) Directive implementing the OECD’s Pillar Two and the proposal for a debt-equity bias reduction allowance (DEBRA) feature rules that target and limit interest deduction as the need for these still exists. However, in case C-484/19 Lexel from 2021, the Court of Justice of the European Union (CJEU) struck down the Swedish targeted interest deduction legislation of 2013 ap

Assessing the decennial, reassessing the global : Understanding European Union normative power in global politics

This concluding article assesses the past decade of international scholarship on the European Union (EU) and normative power as represented by the contributions to the special issue. It argues that the normative power approach (NPA) makes it possible to explain, understand and judge the EU in global politics by rethinking the nature of power and actorness in a globalizing, multilateralizing and mu

The 2012 Danish Presidency of the Council of the European Union : bridging exclusion

"You're an out, a small out, and you're new. We don't want to hear from you."(Nicolas Sarkozy, in Barker and Parker, 2011)Holding the rotating Presidency of the Council of Ministers of the European Union (EU) is a challenging task for any Member State, but in the context of the global financial and eurozone crisis, the perceived decline of EU influence in the world and the growing resentment of EU

Exploring total economic values in an emerging urban circular wastewater system

Circular water management has the potential to close resource and material loops within and across value chains. In the water industry, circular municipal wastewater management through industrial urban symbiosis (IUS) is recognized as a solution to overcome water scarcity in urban environments. IUS involves collaboration between actors with different organizational backgrounds, which can lead to i

MafB-dependent neurotransmitter signaling promotes β cell migration in the developing pancreas

Hormone secretion from pancreatic islets is essential for glucose homeostasis and loss or dysfunction of islet cells is a hallmark of type 2 diabetes. Maf transcription factors are critical for establishing and maintaining adult endocrine cell function. However, during pancreas development, MafB is not only expressed in insulin- and glucagon-producing cells, but also Neurog3+ endocrine progenitor

Antibiotic prophylaxis and its effect on postprocedural adverse events in endoscopic retrograde cholangiopancreatography for primary sclerosing cholangitis

BACKGROUND AND AIM: Primary sclerosing cholangitis (PSC) is characterized by multiple strictures of the biliary tree. Patients with PSC frequently require repeated endoscopic retrograde cholangiopancreatography (ERCP) procedures. These procedures are encumbered by an increased incidence of infectious adverse events such as cholangitis. Evidence regarding whether antibiotic prophylaxis (AP) should

Improved chemical recyclability of 2,5-furandicarboxylate polyesters enabled by acid-sensitive spirocyclic ketal units

Incorporating hydrolytically sensitive functional groups into polymer backbones provides a feasible strategy to trigger their degradation to the starting monomers, thus enabling chemical recycling of the material. Here, we present two series of copolyesters in which a biobased spirocyclic ketal-functional diester monomer was incorporated into poly(butylene 2,5-furandicarboxylate) (PBLF) and poly(h