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Electric Road Systems for Electric Vehicle Long-Distance Travel : A Multi-Agent Simulation Approach

Electric road systems (ERSs) present a transformative advancement in transportation electrification, offering continuous charging capabilities for electric vehicles (EVs) during travel. This innovation has the potential to significantly mitigate range anxiety by enabling in-motion charging, thereby enhancing the overall efficiency of electric mobility, and reducing the frequency of charging stops

Digitala daglönare i gig-ekonomin - En rättsvetenskaplig studio av arbetstagarbegreppet

De senaste åren har den digitaliserade ekonomin etablerats i Sverige. En del av utvecklingen är plattformsarbete eller gig-jobb, som innebär att korta uppdrag åt flera uppdragsgivare förmedlas via en digital delningsplattform eller app. Rättsreglerna är uppbyggda binärt, vilket förenklat innebär att det finns två möjliga system: det ena gäller för dem som är arbetstagare och det andra för dem som

PON-P3: Accurate Prediction of Pathogenicity of Amino Acid Substitutions

Different types of information are combined during variation interpretation. Computational predictors, most often pathogenicity predictors, provide one type of information for this purpose. These tools are based on various kinds of algorithms. Although the American College of Genetics and the Association for Molecular Pathology guidelines classify variants into five categories, practically all pat

Impact of segmental body composition on metabolic dysfunction-associated fatty liver disease in Chinese children

Purpose: This study aimed to assess the relationship between regional body composition and metabolic dysfunction-associated fatty liver disease (MAFLD) in Chinese children.Methods: In this study, 1399 children aged 7–14 years were included. Liver steatosis was assessed using the controlled attenuation parameter (CAP) measured through Fibroscan. MAFLD is defined as the presence of liver steatosis a

ctDNA as an Objective Marker for Postoperative Residual Disease in Primary Advanced High-Grade Serous Ovarian Cancer

Background/Objectives: The surgeon’s subjective intraoperative evaluation is the standard of care to assess postoperative residual disease (RD) in advanced epithelial ovarian cancer (EOC). We investigated the feasibility of ctDNA as an objective marker for postoperative RD. Methods: This prospective study included 27 patients with advanced ovarian cancer (FIGO IIIA1–IVB) who underwent primary surg

Targeting TUBG1 in RB1-negative tumors

The disruption of microtubule dynamics serves as a pivotal strategy for eliminating tumor cells, despite its accompanying toxicities affecting non-tumor cells. This study investigates the potential of selectively targeting γ-tubulin1 (TUBG1) as a therapeutic strategy in cancer treatment. By elucidating the TUBG1-E2F1-retinoblastoma protein (RB1) network, we introduce a novel compound, 4-(6-((3-Met

National Pre-Authorisation Schemes and the EU's Demands for Objectivity Safeguards – Allowing Policy Discretion while Streamlining Administrative Process

The chapter focuses on how process is reviewed in the general framework of EU legal analysis applicable to national pre-authorisation schemes. By examining the model of judicial review developed by the Court of Justice in this regard, I hope to enrich the discussion on what process federalism within the Union can look like and how it may function. After some brief explanations regarding the charac

Healthy ageing for older adult people with intellectual disability : a scoping review

BACKGROUND: The increasing longevity of people with intellectual disability creates a need for a healthy-ageing perspective, translated into evidence-based interventions in this multi-morbidity group. Accordingly, the aim of this scoping review was to identify, summarise and analyse the empirical research on healthy ageing in older adults with intellectual disability.METHODS: This review was based

Excitement is not the only experience

Expectations of what constitutes a positive customer experience have changed over time. Developments in technology and digital services have enabled new kinds of customer experience. As have new store formats and diversified retail offerings. Regardless of the form it has taken, customer experience has always been of paramount importance to retail managers. And it continues to be so. Over 50% of p

Messy customer journey self-mapping

The new retail landscape is complex. New types of touchpoints and new store formats mean messy, non-linear customer journeys with multiple online and offline touchpoints. If we want to understand these journeys, and what value customers derive from new and innovative touchpoints, we must use methods that allow them to explain their own complex customer journeys in all their messy glory!

Long term inguinal pain comparing TEP to Lichtenstein repair : the TEPLICH RCT 8 years follow-up

Purpose: To investigate long-term chronic postoperative inguinal pain (CPIP), QoL and recurrence in patients with a primary inguinal hernia comparing TEP to Lichtenstein. Material and methods: A questionnaire-based follow-up containing the Inguinal Pain Questionnaire (IPQ), the Cunningham Pain Scale and SF-36 was done 8 years after the TEPLICH RCT. The main objective was non-ignorable pain last we

Home, Sweet Home: Returns to Returning in the Age of Mass Migration

Despite significant circular migration flows historically and today, their economic impacts remain understudied. Using data on predominantly rural Swedish migrants who returned from the US during the Age of Mass Migration we estimate returns to temporary migration in terms of wealth, income, demographic and social outcomes. We find substantial wealth effects but limited evidence of increased labor