This study tests the reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H&N35) and version 3.0 of the EORTC Core Questionnaire (QLQ-C30) in 622 head and neck cancer patients from 12 countries. The patients completed the QLQ-C30, the QLQ-H&N35 and a debriefing questionnaire before antineoplastic treatment or at

Background - Circulating adiponectin is a marker for insulin sensitivity, derived from fat cells. It is largely unknown if adiponectin is also an independent marker for early atherosclerosis. Methods and Results - Plasma adiponectin levels were measured in 373 men and 514 women of middle-age by a time-resolved immunofluorometric assay. The subjects were sampled stratified for degree of insulin sen

We present the first implementation of linear response theory for the coupled cluster/molecular mechanics (CC/MM) method. This model introduces polarization effects into a quantum mechanical/molecular mechanical (QM/MM) framework using a self-consistent procedure while electrostatic effects are modeled by assigning partial charges to the MM molecules and a van der Waals potential describes dispers

Rat adipocyte cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) appears to be dually regulated in intact cells by serine phosphorylations induced by isoprenaline and insulin, respectively (Degerman, E., Smith, C. J., Tornqvist, H., Vasta, V., Belfrage, P., and Manganiello, V. C. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 533-537; Smith, C. J., Vasta, V., Degerman, E., Belfrage, P., and Manganiello, V.

A succession of 26 conodont zones and 63 successive subzones and conodont faunas have been identified in the exposed latest Landovery to latest Ludlow strata of Gotland, Sweden. All zones, and several of the subzones and faunas, have been identified elsewhere on Baltica as well as on other palaeocontinents, indicating that this zonation serves well as the standard zonation for calcareous successio

Popular Abstract in Swedish Denna avhandling söker visa att psykoanalysen slagit in en bärande vägg i sin egen teori genom att avfärda det psykiska energibegreppet. Eftersom överbringande av information kräver energi (Brillouin) hamnar vi förutan ett psykiskt energibegrepp i epifenomenalism och cartesiansk dualism. Därmed skulle Darwin s a s ställas utanför psykologin. Psykisk energi kan också visThis thesis purports to prove the logical necessity of the psychic energy concept discarded by modern psychoanalysis by linking the "evolutionistic argument" against epiphenomenalism to Brillouin´s negentropy principle. If our conscious awareness of affects and other psychological events should be attributed a signal value at all, they must necessarily exercise effect on the soma. This presupposes

Popular Abstract in Swedish Denna studie visar betydelsen av ökad idrottsundervisning, fysisk aktivitet och extra motorisk träning i skolan. Undersökningen är en delstudie i Bunkefloprojektet - en hälsofrämjande livsstil. Interventionen består i att två årskullar elever har en obligatorisk rörelselektion varje skoldag. Motorikobservationer med MUGI observationsschema som underlag genomförs varje åThe aim of this thesis is to study effects of an extension of physical education/activity and motor training on motor skills, attention and cognition during a period of three years. Another aim is to develop a test, MUGI observationsschema, which could be useful in charting motor skills of school pupils. The study has two intervention groups (n=152) that have physical activity and motor training o

Objective. To examine if changes in serum cartilage oligomeric matrix protein (COMP) correlate with the development of cartilage damage, as measured by histological grading, in corticosteroid-treated animals with collagen-induced arthritis (CIA). Methods. DA rats with established CIA were treated with corticosteroids (betamethasone, 0.1 mg/kg body weight) or placebo (saline) intraperitoneally once

The paper treats jitter estimation for alignment of a set of signals which contains several unknown classes of waveforms. The motivating application is epileptic EEG spikes. where alignment prior to clustering and averaging is desired. The assumption that the signal waveforms are unknown precludes the use of classical techniques, notably matched filtering. Instead we treat two other classes of met

Popular Abstract in Swedish Stroke är en av de ledande dödsorsakerna i västvärlden och det finns idag ingen behandling för funktionell återställning. Efter stroke ökar den striatala neurogenesen och de nybildade neuroblasterna vandrar mot det skadade området. Denna respons har ansetts vara av akut och övergående art. I denna avhandling har en modell av experimentell stroke använts (2 h of middle cStroke is a leading cause of death and disability for which there is no treatment for functional recovery. Following stroke, striatal neurogenesis is increased, with newly formed neuroblasts migrating towards the damage. This response has so far been considered acute and transient. In this thesis, a model of experimental stroke (2 h of middle cerebral artery occlusion, MCAO) used to study three a

Popular Abstract in Swedish Forskarna inom Chicagoskolan var de första i ett akademiskt ramverk som systematiskt och etnografiskt satte gruppen och människan i centrum i en modern urban kontext. Det hade förekommit andra som skrivit om industrialism, modernism, urbanitet och de fattiga i slummen, men inte på ett lika systematiskt och genomträngande sätt som Chicagoskolan. Skolans strävan att föranThe main purpose of my thesis is to investigate how the Chicago School in urban sociology, that was active between 1915 and 1935, developed and why it produced so many classical monographs during a period of about ten to fifteen years. To outline the historical reasons for the School to develop I have chosen to view the historical context as a field with different actors. Another related and overa

A non-associated plasticity theory for granular materials has been developed in Part 1 based on the concept of a characteristic stress state of vanishing incremental dilation. The model is fully three-dimensional and is defined by six material parameters: two for elastic stiffness, one for plastic stiffness, two for the shapes of yield and plastic potential surfaces and one for the dilation at fai

Presence–absence surveys are a commonly used method for monitoring broad-scale changes in wildlife distributions. However, the lack of power of these surveys for detecting population trends is problematic for their application in wildlife management. Options for improving power include increasing the sampling effort or arbitrarily relaxing the type I error rate. We present an alternative, whereby

Abstract is not available