Age-related macular degeneration (AMD) is a progressive disease of the central retina and the leading cause of irreversible vision loss in the western world. The involvement of abnormal complement activation in AMD has been suggested by association of variants in genes encoding complement proteins with disease development. A low-frequency variant (p.P167S) in the complement component C9 (C9) gene

The first step of the adaptive immune response involves the interaction of T cells that express T-cell receptors (TCRs) with peptide-loaded major histocompatibility complexes expressed by antigen-presenting cells (APCs). Exactly how this leads to activation of the TCR and to downstream signaling is uncertain, however. Recent findings suggest that one of the key events is the exclusion of the large

The use of wood as construction material in multi-story buildings increased in Europe during the last decades. Wood buildings are more sensitive to dynamic loading compared to conventional concrete buildings, especially in terms of vibroacoustic comfort. Furthermore, it is more difficult to predict the accurate response due to dynamic loading for wood buildings. This is due to factors such as a co

The newly developed website ’Den botaniska skattkammaren’ [The botanic treasury; www.botskatt.se] is presented. It is intended to be gradually filled with miscellaneous information about vascular plant taxa found in, or expected to be found in Swedish nature (i.e. including all kinds of ephemerals and garden escapes). The material included will partly be newly produced, partly reproduced with permThe newly developed website ’Den botaniska skattkammaren’ [The botanic treasury; www.botskatt.se] is presented. It is intended to be gradually filled with miscellaneous information about vascular plant taxa found in, or expected to be found in Swedish nature (i.e. including all kinds of ephemerals and garden escapes). The material included will partly be newly produced, partly reproduced with perm

OBJECTIVE. Previous studies have shown the possibility to reduce radiation dose in abdominal CT by 25–50% without negatively affecting detection of liver lesions. How radiation dose reduction affects characterization of liver metastases is not as well known. The objective of this study was to investigate how different levels of simulated dose reduction affect the detection and characterization of

This study argues that Brexit is as much an internal UK crisis of law, identity politics and democracy as it is the EU crisis of integration. Does Brexit bring us a new insight into how the legal order of the EU and its Member States are interrelated? Does it throw a new light on the EU law’s ability to produce a sense of collective European identity and solidarity which transcends national borderThis study argues that Brexit is as much an internal UK crisis of law, identity politics and democracy as it is the EU crisis of integration. Does Brexit bring us a new insight into how the legal order of the EU and its Member States are interrelated? Does it throw a new light on the EU law’s ability to produce a sense of collective European identity and solidarity which transcends national border

Ling Hon Lam encourages us to think of emotions in terms of space; when we sympathize with a character in a play or feel something for another person, that emotion takes place, for it moves us outside ourselves. In Chinese this relation between space and emotion is described by the term qingjing; a scenery of feeling or in Ling’s translation an “emotion-realm”.

A novel 2D particle tracking method, that uses 1) iteration, 2) fastquadratic sub-pixel estimation (with only 28 multiplications per movement), and3) a previous kernel, has been evaluated and compared with a full-searchblock-matching method. The comparison with high-frequency ultrasound data (40MHz) was conducted in silico and on phantoms, which comprised lateral, diagonal,and ellipsoidal movement

We have previously shown that there is a distinct longitudinal movement of the arterial wall during a cardiac cycle. This movement is larger in the intima-media region than in the adventitial region which introduces a substantial shear strain within the arterial wall. Our previously developed echo-tracking algorithm measured this shear strain by tracking two separate echoes, one in the intima-medi

This article responds to previous efforts to calculate diplomatic prestige while adapting these methodologies to the exigencies of digital diplomacy. In particular, we are interested in how digital diplomacy provides opportunities for diplomatic actors lacking in material resources to overcome prestige deficits. We adapt approaches used in earlier studies to calculate the material and ideational c

Aid transparency received a welcome boost in December 2011 when a critical mass of donors signed up to the International Aid Transparency Initiative (IATI), an electronic registry through which all aid expenditure is published using the same criteria. IATI launched with statements about increased effectiveness, improved collaboration and better decisions based on greater transparency. This article

Behandlar symbolik och nordisk respektive romersk mytologi i den bildkonst som framställer Karl Johan efter ankomsten till Sverige och Norge.

Behandlar symbolik och nordisk respektive romersk mytologi i den bildkonst som framställer Karl Johan efter ankomsten till Sverige och Norge.